SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mgt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B82_A_ADNA1001_1
(CLASS B ACID
PHOSPHATASE)
5mgt KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER 1

(Homo
sapiens)
5 / 10 GLU C 186
TRP C 165
GLY C 182
ASP C 183
TYR C 201
None
1.13A 2b82A-5mgtC:
undetectable
2b82A-5mgtC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)
5mgt KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER 1

(Homo
sapiens)
4 / 6 LEU C 144
LYS C 104
GLN C 100
LEU C 106
None
0.87A 3h5gB-5mgtC:
undetectable
3h5gC-5mgtC:
undetectable
3h5gB-5mgtC:
undetectable
3h5gC-5mgtC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])
5mgt KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER 1

(Homo
sapiens)
3 / 3 ASP C 136
LYS C 135
ASP C 134
None
0.86A 4a7tA-5mgtC:
undetectable
4a7tA-5mgtC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)
5mgt KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER 1

(Homo
sapiens)
4 / 8 ILE C 190
ILE C 132
LEU C 138
ILE C 192
None
0.88A 4dtaB-5mgtC:
undetectable
4dtaB-5mgtC:
undetectable