SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mgy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)		 5mgy FAD:PROTEIN FMN
TRANSFERASE
(Pseudomonas
stutzeri) 		5 / 12 TYR H 188
LEU H  72
LEU H  75
TYR H  48
ILE H 209
 None
 1.17A 1fmlA-5mgyH:
undetectable		 1fmlA-5mgyH:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 5mgy FAD:PROTEIN FMN
TRANSFERASE
(Pseudomonas
stutzeri) 		5 / 12 TYR H 188
LEU H  72
LEU H  75
TYR H  48
ILE H 209
 None
 1.17A 1fmlB-5mgyH:
undetectable		 1fmlB-5mgyH:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 5mgy FAD:PROTEIN FMN
TRANSFERASE
(Pseudomonas
stutzeri) 		5 / 11 ALA H 215
LEU H 245
LEU H 213
ILE H 229
ALA H 228
 None
 1.06A 1ha2A-5mgyH:
undetectable		 1ha2A-5mgyH:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5mgy FAD:PROTEIN FMN
TRANSFERASE
(Pseudomonas
stutzeri) 		4 / 7 LEU H  72
LEU H 192
MET H 105
LEU H  79
 None
 1.10A 1kt3A-5mgyH:
undetectable		 1kt3A-5mgyH:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5mgy FAD:PROTEIN FMN
TRANSFERASE
(Pseudomonas
stutzeri) 		4 / 8 ASP H 121
SER H 120
ILE H 320
GLY H 319
 None
 0.66A 1me7A-5mgyH:
undetectable		 1me7A-5mgyH:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 5mgy FAD:PROTEIN FMN
TRANSFERASE
(Pseudomonas
stutzeri) 		4 / 6 LEU H 177
ALA H 174
LEU H 164
SER H 165
 None
 1.34A 1tyrA-5mgyH:
undetectable		 1tyrA-5mgyH:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))		 5mgy FAD:PROTEIN FMN
TRANSFERASE
(Pseudomonas
stutzeri) 		5 / 12 SER H 292
ALA H 112
TYR H 188
GLY H 113
LEU H 116
 None
 1.34A 1vpoH-5mgyH:
undetectable
1vpoL-5mgyH:
undetectable		 1vpoH-5mgyH:
24.54
1vpoL-5mgyH:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5mgy FAD:PROTEIN FMN
TRANSFERASE
(Pseudomonas
stutzeri) 		4 / 7 VAL H 286
SER H 253
LEU H 306
THR H 270
 None
 1.04A 2f78A-5mgyH:
undetectable		 2f78A-5mgyH:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5mgy FAD:PROTEIN FMN
TRANSFERASE
(Pseudomonas
stutzeri) 		4 / 8 PHE H 181
SER H 183
ALA H 112
LEU H 109
 None
 1.00A 2o01A-5mgyH:
undetectable		 2o01A-5mgyH:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_K_SAMK302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 5mgy FAD:PROTEIN FMN
TRANSFERASE
(Pseudomonas
stutzeri) 		5 / 12 GLY H 298
SER H 253
VAL H 286
LEU H 303
LEU H 116
 None
 1.48A 3cjtK-5mgyH:
undetectable		 3cjtK-5mgyH:
25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 5mgy FAD:PROTEIN FMN
TRANSFERASE
(Pseudomonas
stutzeri) 		4 / 8 GLY H 187
SER H  46
ASP H 297
THR H 252
 None
None
MG  H 401 (-3.0A)
None
 0.78A 3pwwA-5mgyH:
undetectable		 3pwwA-5mgyH:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 5mgy FAD:PROTEIN FMN
TRANSFERASE
(Pseudomonas
stutzeri) 		4 / 7 PHE H 323
ALA H 322
THR H 337
LEU H 312
 None
 0.97A 3t3sC-5mgyH:
undetectable		 3t3sC-5mgyH:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 5mgy FAD:PROTEIN FMN
TRANSFERASE
(Pseudomonas
stutzeri) 		5 / 11 GLY H 217
TRP H 225
LEU H 245
GLY H 247
ALA H 285
 None
 1.18A 4l6v1-5mgyH:
undetectable
4l6v6-5mgyH:
undetectable		 4l6v1-5mgyH:
17.90
4l6v6-5mgyH:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UAC_A_ACRA501_2
(CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-))		 5mgy FAD:PROTEIN FMN
TRANSFERASE
(Pseudomonas
stutzeri) 		4 / 7 SER H  46
GLU H 208
ASP H 255
THR H 252
 None
 1.26A 4uacA-5mgyH:
undetectable		 4uacA-5mgyH:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 5mgy FAD:PROTEIN FMN
TRANSFERASE
(Pseudomonas
stutzeri) 		5 / 12 THR H 301
SER H 183
GLY H 122
GLY H 276
LEU H 128
 MG  H 401 (-3.6A)
None
None
None
None
 1.47A 4uinH-5mgyH:
undetectable
4uinL-5mgyH:
undetectable		 4uinH-5mgyH:
19.10
4uinL-5mgyH:
21.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 5mgy FAD:PROTEIN FMN
TRANSFERASE
(Pseudomonas
stutzeri) 		6 / 12 PHE H 124
LEU H 128
ASP H 180
PRO H 273
THR H 301
VAL H 305
 None
None
None
None
MG  H 401 (-3.6A)
None
 0.80A 4xdrA-5mgyH:
13.9		 4xdrA-5mgyH:
31.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_E_SAME501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5mgy FAD:PROTEIN FMN
TRANSFERASE
(Pseudomonas
stutzeri) 		5 / 9 LEU H  75
GLY H  73
VAL H 193
LEU H 192
ARG H 196
 None
 1.07A 5o96E-5mgyH:
undetectable
5o96F-5mgyH:
undetectable		 5o96E-5mgyH:
22.94
5o96F-5mgyH:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 5mgy FAD:PROTEIN FMN
TRANSFERASE
(Pseudomonas
stutzeri) 		4 / 6 ARG H 257
ALA H 231
THR H 334
ALA H 284
 None
 1.18A 6ma6A-5mgyH:
undetectable		 6ma6A-5mgyH:
14.52