SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mhf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 8 PHE A 155
GLY A 152
ARG A 153
LEU A 463
 None
 1.17A 1gsfA-5mhfA:
undetectable		 1gsfA-5mhfA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 8 PHE A 155
GLY A 152
ARG A 153
LEU A 463
 None
 1.17A 1gsfB-5mhfA:
undetectable		 1gsfB-5mhfA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 8 PHE A 155
GLY A 152
ARG A 153
LEU A 463
 None
 1.17A 1gsfD-5mhfA:
undetectable		 1gsfD-5mhfA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 7 SER A 589
HIS A 594
ARG A 562
TYR A 582
 NAG  A 904 ( 4.7A)
None
None
None
 1.11A 1ibgL-5mhfA:
2.0		 1ibgL-5mhfA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 6 PHE A 440
PHE A 402
GLU A 484
GLY A 444
 None
None
6A9  A 903 ( 3.9A)
None
 1.13A 1icuA-5mhfA:
undetectable
1icuB-5mhfA:
undetectable		 1icuA-5mhfA:
16.43
1icuB-5mhfA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 6 PHE A 402
GLU A 484
GLY A 444
PHE A 440
 None
6A9  A 903 ( 3.9A)
None
None
 1.16A 1icuA-5mhfA:
undetectable
1icuB-5mhfA:
undetectable		 1icuA-5mhfA:
16.43
1icuB-5mhfA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 6 PHE A 440
PHE A 402
GLU A 484
GLY A 444
 None
None
6A9  A 903 ( 3.9A)
None
 1.17A 1kqbA-5mhfA:
undetectable
1kqbB-5mhfA:
undetectable		 1kqbA-5mhfA:
undetectable
1kqbB-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		3 / 3 ALA A 605
VAL A 607
TRP A 837
 None
 0.94A 1tkqA-5mhfA:
undetectable		 1tkqA-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 6 TRP A 147
HIS A 150
THR A  96
PRO A  99
 None
 1.28A 2ez7A-5mhfA:
undetectable		 2ez7A-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 12 PHE A 432
GLY A 469
GLY A 473
ASP A 460
LEU A  92
 None
 1.08A 2hmyB-5mhfA:
undetectable		 2hmyB-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 12 ASN A 281
LEU A 299
GLY A 298
GLN A 320
MET A 118
 None
 1.43A 2q7lA-5mhfA:
undetectable		 2q7lA-5mhfA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 6 GLU A 804
TYR A 746
PHE A 819
PRO A 436
 6A9  A 903 ( 4.9A)
6A9  A 903 (-3.9A)
6A9  A 903 ( 4.9A)
6A9  A 903 (-4.3A)
 1.45A 2vmyA-5mhfA:
undetectable		 2vmyA-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 12 ASN A 281
LEU A 299
GLY A 298
GLN A 320
MET A 118
 None
 1.42A 2yhdA-5mhfA:
undetectable		 2yhdA-5mhfA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		3 / 3 LEU A 686
TRP A 720
TYR A 688
 None
 0.96A 3aicA-5mhfA:
undetectable		 3aicA-5mhfA:
6.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		3 / 3 LEU A 686
TRP A 720
TYR A 688
 None
 0.97A 3aicB-5mhfA:
undetectable		 3aicB-5mhfA:
6.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		3 / 3 LEU A 686
TRP A 720
TYR A 688
 None
 1.00A 3aicE-5mhfA:
undetectable		 3aicE-5mhfA:
6.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		3 / 3 LEU A 686
TRP A 720
TYR A 688
 None
 0.99A 3aicG-5mhfA:
undetectable		 3aicG-5mhfA:
6.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		3 / 3 PRO A 693
LEU A 595
ARG A 593
 None
 0.86A 3aqiB-5mhfA:
undetectable		 3aqiB-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 4 SER A 337
GLY A 336
GLY A 176
GLY A 180
 None
 0.93A 3bogB-5mhfA:
undetectable
3bogD-5mhfA:
undetectable		 3bogB-5mhfA:
undetectable
3bogD-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 10 ILE A 399
SER A 393
GLY A 398
SER A 824
LEU A 463
 None
 1.43A 3ik6B-5mhfA:
undetectable
3ik6E-5mhfA:
undetectable		 3ik6B-5mhfA:
15.60
3ik6E-5mhfA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		3 / 3 ASN A 508
ASP A 448
ARG A 748
 None
6A9  A 903 (-3.0A)
None
 0.77A 3k13C-5mhfA:
undetectable		 3k13C-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		3 / 3 ASP A 140
ARG A 133
ARG A 817
 None
MLY  A 131 ( 4.1A)
None
 0.94A 3k37A-5mhfA:
undetectable		 3k37A-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 7 GLN A 502
GLU A 449
GLU A 484
PRO A 436
 None
None
6A9  A 903 ( 3.9A)
6A9  A 903 (-4.3A)
 1.42A 3ql6A-5mhfA:
undetectable		 3ql6A-5mhfA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		3 / 3 PHE A 149
SER A 393
GLN A 389
 MLY  A 366 ( 4.8A)
None
None
 0.83A 3smtA-5mhfA:
undetectable		 3smtA-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 12 GLY A 336
LEU A 236
HIS A 232
ASP A 238
GLY A 180
 None
 1.16A 4blvA-5mhfA:
undetectable		 4blvA-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 7 GLU A 490
ARG A 438
GLY A 104
ARG A  98
 None
 1.07A 4fgzA-5mhfA:
undetectable		 4fgzA-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 8 PHE A 649
ARG A 598
ASP A 638
SER A 703
 None
 1.07A 4lv9A-5mhfA:
undetectable
4lv9B-5mhfA:
undetectable		 4lv9A-5mhfA:
11.36
4lv9B-5mhfA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 6 LEU A 719
ASN A 756
LEU A 784
GLU A 783
 None
None
None
MLY  A 779 ( 2.9A)
 1.23A 4nc3A-5mhfA:
2.8		 4nc3A-5mhfA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_E_IPHE101_0
(INSULIN)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 11 LEU A 531
HIS A 539
LEU A 538
LEU A 624
LEU A 615
 SME  A 519 ( 3.7A)
None
None
None
None
 1.10A 4p65E-5mhfA:
undetectable
4p65F-5mhfA:
undetectable
4p65J-5mhfA:
undetectable
4p65L-5mhfA:
undetectable		 4p65E-5mhfA:
undetectable
4p65F-5mhfA:
undetectable
4p65J-5mhfA:
undetectable
4p65L-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 11 HIS A 159
THR A 247
THR A 188
GLY A 250
THR A 355
 None
 1.46A 4qvlV-5mhfA:
undetectable
4qvlb-5mhfA:
undetectable		 4qvlV-5mhfA:
14.72
4qvlb-5mhfA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 11 HIS A 159
THR A 247
THR A 188
GLY A 250
THR A 355
 None
 1.46A 4qvlH-5mhfA:
undetectable
4qvlN-5mhfA:
undetectable		 4qvlH-5mhfA:
14.72
4qvlN-5mhfA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 11 HIS A 159
THR A 247
THR A 188
GLY A 250
THR A 355
 None
 1.47A 4qvmV-5mhfA:
undetectable
4qvmb-5mhfA:
undetectable		 4qvmV-5mhfA:
14.72
4qvmb-5mhfA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 11 HIS A 159
THR A 247
THR A 188
GLY A 250
THR A 355
 None
 1.47A 4qvmH-5mhfA:
undetectable
4qvmN-5mhfA:
undetectable		 4qvmH-5mhfA:
14.72
4qvmN-5mhfA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 11 HIS A 159
THR A 247
THR A 188
GLY A 250
THR A 355
 None
 1.45A 4qvwV-5mhfA:
undetectable
4qvwb-5mhfA:
undetectable		 4qvwV-5mhfA:
14.72
4qvwb-5mhfA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 11 HIS A 159
THR A 247
THR A 188
GLY A 250
THR A 355
 None
 1.44A 4qvwH-5mhfA:
undetectable
4qvwN-5mhfA:
undetectable		 4qvwH-5mhfA:
14.72
4qvwN-5mhfA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 11 HIS A 159
THR A 247
THR A 188
GLY A 250
THR A 355
 None
 1.45A 4qw0V-5mhfA:
undetectable
4qw0b-5mhfA:
undetectable		 4qw0V-5mhfA:
14.72
4qw0b-5mhfA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 11 HIS A 159
THR A 247
THR A 188
GLY A 250
THR A 355
 None
 1.45A 4qw0H-5mhfA:
undetectable
4qw0N-5mhfA:
undetectable		 4qw0H-5mhfA:
14.72
4qw0N-5mhfA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 11 HIS A 159
THR A 247
THR A 188
GLY A 250
THR A 355
 None
 1.44A 4qw1V-5mhfA:
undetectable
4qw1b-5mhfA:
undetectable		 4qw1V-5mhfA:
14.72
4qw1b-5mhfA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 11 HIS A 159
THR A 247
THR A 188
GLY A 250
THR A 355
 None
 1.44A 4qw1H-5mhfA:
undetectable
4qw1N-5mhfA:
undetectable		 4qw1H-5mhfA:
14.72
4qw1N-5mhfA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 11 HIS A 159
THR A 247
THR A 188
GLY A 250
THR A 355
 None
 1.44A 4qwuV-5mhfA:
undetectable
4qwub-5mhfA:
undetectable		 4qwuV-5mhfA:
14.72
4qwub-5mhfA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 11 HIS A 159
THR A 247
THR A 188
GLY A 250
THR A 355
 None
 1.44A 4qwuH-5mhfA:
undetectable
4qwuN-5mhfA:
undetectable		 4qwuH-5mhfA:
14.72
4qwuN-5mhfA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 7 PHE A 206
ARG A 186
THR A 168
LEU A 167
 None
 0.87A 5b1bN-5mhfA:
undetectable
5b1bW-5mhfA:
undetectable		 5b1bN-5mhfA:
undetectable
5b1bW-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 7 PHE A 206
ARG A 186
THR A 168
LEU A 167
 None
 0.83A 5b3sN-5mhfA:
undetectable
5b3sW-5mhfA:
undetectable		 5b3sN-5mhfA:
undetectable
5b3sW-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 11 HIS A 159
THR A 247
THR A 188
GLY A 250
THR A 355
 None
 1.47A 5bxnV-5mhfA:
undetectable
5bxnb-5mhfA:
undetectable		 5bxnV-5mhfA:
14.72
5bxnb-5mhfA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 11 HIS A 159
THR A 247
THR A 188
GLY A 250
THR A 355
 None
 1.47A 5bxnH-5mhfA:
undetectable
5bxnN-5mhfA:
undetectable		 5bxnH-5mhfA:
14.72
5bxnN-5mhfA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 11 HIS A 159
THR A 247
THR A 188
GLY A 250
THR A 355
 None
 1.46A 5cz7H-5mhfA:
undetectable
5cz7N-5mhfA:
undetectable		 5cz7H-5mhfA:
14.72
5cz7N-5mhfA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 11 HIS A 159
THR A 247
THR A 188
GLY A 250
THR A 355
 None
 1.47A 5d0xV-5mhfA:
undetectable
5d0xb-5mhfA:
undetectable		 5d0xV-5mhfA:
14.72
5d0xb-5mhfA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 11 HIS A 159
THR A 247
THR A 188
GLY A 250
THR A 355
 None
 1.48A 5d0xH-5mhfA:
undetectable
5d0xN-5mhfA:
undetectable		 5d0xH-5mhfA:
14.72
5d0xN-5mhfA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 5 PRO A 249
HIS A 159
LEU A 117
PHE A 155
 None
 1.28A 5igjA-5mhfA:
1.0		 5igjA-5mhfA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 12 VAL A 456
LEU A 392
GLY A 398
PHE A 103
ILE A 399
 None
 1.11A 5vooD-5mhfA:
undetectable		 5vooD-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 12 GLY A 434
VAL A 455
LEU A 454
GLY A 450
PRO A 515
 None
None
None
None
SME  A 519 ( 4.7A)
 1.01A 5wyqA-5mhfA:
undetectable		 5wyqA-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 8 PHE A 206
ARG A 186
THR A 168
LEU A 167
 None
 0.83A 5xdxN-5mhfA:
undetectable
5xdxW-5mhfA:
undetectable		 5xdxN-5mhfA:
undetectable
5xdxW-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_D_HFGD1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 12 LEU A 323
VAL A 321
PRO A 246
THR A 247
THR A 355
 None
 1.49A 5xipD-5mhfA:
undetectable		 5xipD-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 8 PHE A 206
ARG A 186
THR A 168
LEU A 167
 None
 0.74A 5zcoA-5mhfA:
undetectable
5zcoJ-5mhfA:
undetectable		 5zcoA-5mhfA:
undetectable
5zcoJ-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		5 / 9 HIS A 361
GLY A 156
LEU A 395
ARG A 153
ASP A 460
 None
 1.33A 6c2mC-5mhfA:
undetectable		 6c2mC-5mhfA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 5 GLN A 457
VAL A 455
PRO A 515
THR A 823
 SME  A 519 ( 4.7A)
None
SME  A 519 ( 4.7A)
None
 1.30A 6cduI-5mhfA:
undetectable
6cduJ-5mhfA:
undetectable		 6cduI-5mhfA:
undetectable
6cduJ-5mhfA:
undetectable