SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mi0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5mi0 RETICULOCYTE
BINDING-LIKE PROTEIN
5,RETICULOCYTE
BINDING PROTEIN 5
(Plasmodium
falciparum) 		5 / 9 LEU A 475
ASP A 162
LEU A 164
THR A 482
THR A 428
 None
 1.42A 1hzeA-5mi0A:
undetectable
1hzeB-5mi0A:
undetectable		 1hzeA-5mi0A:
12.91
1hzeB-5mi0A:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5mi0 RETICULOCYTE
BINDING-LIKE PROTEIN
5,RETICULOCYTE
BINDING PROTEIN 5
(Plasmodium
falciparum) 		5 / 9 THR A 428
LEU A 475
ASP A 162
LEU A 164
THR A 482
 None
 1.45A 1hzeA-5mi0A:
undetectable
1hzeB-5mi0A:
undetectable		 1hzeA-5mi0A:
12.91
1hzeB-5mi0A:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 5mi0 RETICULOCYTE
BINDING-LIKE PROTEIN
5,RETICULOCYTE
BINDING PROTEIN 5
(Plasmodium
falciparum) 		5 / 12 GLY A 336
ILE A 193
SER A 192
ALA A 205
ILE A 213
 None
 1.13A 1ve3A-5mi0A:
undetectable		 1ve3A-5mi0A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 5mi0 RETICULOCYTE
BINDING-LIKE PROTEIN
5,RETICULOCYTE
BINDING PROTEIN 5
(Plasmodium
falciparum) 		5 / 12 GLY A 336
ILE A 193
SER A 192
ALA A 205
ILE A 213
 None
 1.13A 1ve3B-5mi0A:
undetectable		 1ve3B-5mi0A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5mi0 RETICULOCYTE
BINDING-LIKE PROTEIN
5,RETICULOCYTE
BINDING PROTEIN 5
(Plasmodium
falciparum) 		3 / 3 LYS A 429
ASP A 382
ASN A 377
 None
 0.88A 2bm9A-5mi0A:
undetectable		 2bm9A-5mi0A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 5mi0 RETICULOCYTE
BINDING-LIKE PROTEIN
5,RETICULOCYTE
BINDING PROTEIN 5
(Plasmodium
falciparum) 		4 / 5 ILE A 175
PRO A 177
PHE A 181
ILE A 328
 None
 1.14A 2hjhA-5mi0A:
undetectable		 2hjhA-5mi0A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 5mi0 MONOCLONAL ANTIBODY
9AD4
(Mus
musculus) 		3 / 3 THR B 119
GLU B 157
HIS B 208
 None
 0.83A 3g1uB-5mi0B:
undetectable		 3g1uB-5mi0B:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 5mi0 RETICULOCYTE
BINDING-LIKE PROTEIN
5,RETICULOCYTE
BINDING PROTEIN 5
(Plasmodium
falciparum) 		4 / 5 PRO A 177
SER A 160
LEU A 468
SER A 472
 None
 1.34A 3ijxH-5mi0A:
undetectable		 3ijxH-5mi0A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5mi0 RETICULOCYTE
BINDING-LIKE PROTEIN
5,RETICULOCYTE
BINDING PROTEIN 5
(Plasmodium
falciparum) 		4 / 8 TYR A 184
LEU A 460
ASP A 461
LYS A 464
 None
 0.96A 3lsfH-5mi0A:
undetectable		 3lsfH-5mi0A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 5mi0 RETICULOCYTE
BINDING-LIKE PROTEIN
5,RETICULOCYTE
BINDING PROTEIN 5
(Plasmodium
falciparum) 		4 / 7 TYR A 184
LEU A 460
ASP A 461
LYS A 464
 None
 1.10A 3lslA-5mi0A:
undetectable
3lslD-5mi0A:
undetectable		 3lslA-5mi0A:
21.64
3lslD-5mi0A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 5mi0 RETICULOCYTE
BINDING-LIKE PROTEIN
5,RETICULOCYTE
BINDING PROTEIN 5
(Plasmodium
falciparum) 		4 / 7 TYR A 184
LEU A 460
ASP A 461
LYS A 464
 None
 1.06A 3lslA-5mi0A:
undetectable
3lslD-5mi0A:
undetectable		 3lslA-5mi0A:
21.64
3lslD-5mi0A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 5mi0 RETICULOCYTE
BINDING-LIKE PROTEIN
5,RETICULOCYTE
BINDING PROTEIN 5
(Plasmodium
falciparum) 		4 / 6 TYR A 184
LEU A 460
ASP A 461
LYS A 464
 None
 1.01A 3lslG-5mi0A:
undetectable		 3lslG-5mi0A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5mi0 MONOCLONAL ANTIBODY
9AD4
(Mus
musculus) 		3 / 3 SER B 212
ALA B 207
VAL B 206
 None
 0.59A 4x1iA-5mi0B:
undetectable		 4x1iA-5mi0B:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YNP_B_SAMB2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)		 5mi0 RETICULOCYTE
BINDING-LIKE PROTEIN
5,RETICULOCYTE
BINDING PROTEIN 5
(Plasmodium
falciparum) 		5 / 10 GLY A 355
ASN A 191
HIS A 187
TYR A 466
ILE A 364
 None
 1.42A 4ynpB-5mi0A:
undetectable		 4ynpB-5mi0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPA_A_SAMA3004_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)		 5mi0 RETICULOCYTE
BINDING-LIKE PROTEIN
5,RETICULOCYTE
BINDING PROTEIN 5
(Plasmodium
falciparum) 		5 / 12 GLY A 355
ASN A 191
HIS A 187
TYR A 466
ILE A 364
 None
 1.47A 4ypaA-5mi0A:
undetectable		 4ypaA-5mi0A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5mi0 MONOCLONAL ANTIBODY
9AD4
(Mus
musculus) 		3 / 3 SER B 212
ALA B 207
VAL B 206
 None
 0.55A 5eypA-5mi0B:
undetectable		 5eypA-5mi0B:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 5mi0 MONOCLONAL ANTIBODY
9AD4
(Mus
musculus) 		3 / 3 SER B 212
ALA B 207
VAL B 206
 None
 0.50A 5xiwC-5mi0B:
undetectable		 5xiwC-5mi0B:
16.39