SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mih'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG1_W_CHDW1059_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	5mih	PA-I GALACTOPHILIC LECTIN (Pseudomonas aeruginosa)	4 / 6	ILE A 26 MET A 67 THR A 95 LEU A 96	None	1.03A	3ag1N-5mihA: undetectable 3ag1W-5mihA: undetectable	3ag1N-5mihA: 14.46 3ag1W-5mihA: 22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ARC_A_LEUA1001_0 (LEUCINE--TRNA LIGASE)	5mih	PA-I GALACTOPHILIC LECTIN (Pseudomonas aeruginosa)	4 / 7	LEU A 55 TYR A 98 ASP A 100 HIS A 50	None None 7NU A 201 ( 2.5A) 7NU A 201 (-3.9A)	1.33A	4arcA-5mihA: undetectable	4arcA-5mihA: 8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BBO_C_ACTC1113_0 (BLR5658 PROTEIN)	5mih	PA-I GALACTOPHILIC LECTIN (Pseudomonas aeruginosa)	4 / 4	ASN A 10 ALA A 12 GLY A 13 THR A 95	None	1.27A	4bboC-5mihA: undetectable	4bboC-5mihA: 24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5F9Z_B_HFGB703_0 (AMINOACYL-TRNA SYNTHETASE)	5mih	PA-I GALACTOPHILIC LECTIN (Pseudomonas aeruginosa)	5 / 12	LEU A 65 PHE A 112 SER A 111 GLU A 5 VAL A 6	None	1.33A	5f9zB-5mihA: undetectable	5f9zB-5mihA: 11.79

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3AG1_W_CHDW1059_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","5mih","PA-I GALACTOPHILIC LECTIN","Pseudomonas aeruginosa",4,"ILE A  26;MET A  67;THR A  95;LEU A  96","None","1.03A","3ag1N-5mihA:undetectable;3ag1W-5mihA:undetectable","3ag1N-5mihA:14.46;3ag1W-5mihA:22.88"],["4ARC_A_LEUA1001_0","LEUCINE--TRNA LIGASE","5mih","PA-I GALACTOPHILIC LECTIN","Pseudomonas aeruginosa",4,"LEU A  55;TYR A  98;ASP A 100;HIS A  50","None;None;7NU A 201 ( 2.5A);7NU A 201 (-3.9A)","1.33A","4arcA-5mihA:undetectable","4arcA-5mihA:8.79"],["4BBO_C_ACTC1113_0","BLR5658 PROTEIN","5mih","PA-I GALACTOPHILIC LECTIN","Pseudomonas aeruginosa",4,"ASN A  10;ALA A  12;GLY A  13;THR A  95","None","1.27A","4bboC-5mihA:undetectable","4bboC-5mihA:24.09"],["5F9Z_B_HFGB703_0","AMINOACYL-TRNA SYNTHETASE","5mih","PA-I GALACTOPHILIC LECTIN","Pseudomonas aeruginosa",5,"LEU A  65;PHE A 112;SER A 111;GLU A   5;VAL A   6","None","1.33A","5f9zB-5mihA:undetectable","5f9zB-5mihA:11.79"]]