SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5min'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 8 ILE A  69
ASN A 112
GLY A  98
LEU A  80
 None
 0.87A 1dzmA-5minA:
undetectable		 1dzmA-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 7 THR A 194
LEU A 225
GLY A 197
LEU A 200
 None
 1.05A 1gtiD-5minA:
undetectable		 1gtiD-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		5 / 11 PHE A  84
ILE A  94
LEU A 149
GLY A  81
PHE A  82
 None
 1.33A 1ju6A-5minA:
undetectable		 1ju6A-5minA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 8 ILE A  94
LEU A 149
GLY A  81
PHE A  82
 None
 0.75A 1rtsA-5minA:
undetectable		 1rtsA-5minA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 7 ILE A  94
LEU A 149
GLY A  81
PHE A  82
 None
 0.67A 1rtsB-5minA:
undetectable		 1rtsB-5minA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 6 LEU A 149
TYR A  95
ILE A 151
GLY A 206
 None
 0.91A 2du8A-5minA:
undetectable		 2du8A-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 6 LEU A 149
TYR A  95
ILE A 151
GLY A 206
 None
 0.95A 2du8B-5minA:
undetectable		 2du8B-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 7 ILE A  94
LEU A 149
GLY A  81
PHE A  82
 None
 0.73A 2tsrA-5minA:
undetectable		 2tsrA-5minA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		5 / 12 SER A 244
ALA A 350
PRO A 351
THR A 348
TYR A 325
 None
CA  A 503 ( 3.9A)
None
None
None
 1.06A 2zifB-5minA:
undetectable		 2zifB-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		3 / 3 PHE A 382
GLN A 231
PHE A   9
 None
 0.78A 3rv5A-5minA:
undetectable		 3rv5A-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 6 ASP A 251
GLY A 247
ASP A 252
THR A 348
 CA  A 502 ( 4.2A)
None
None
None
 1.17A 3vqrA-5minA:
undetectable		 3vqrA-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 5 ASP A 251
GLY A 247
ASP A 252
THR A 348
 CA  A 502 ( 4.2A)
None
None
None
 1.19A 3vqrB-5minA:
undetectable		 3vqrB-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 7 ILE A  94
LEU A 149
GLY A  81
PHE A  82
 None
 0.75A 4iqqB-5minA:
undetectable		 4iqqB-5minA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 7 ILE A  94
LEU A 149
GLY A  81
PHE A  82
 None
 0.78A 4iqqC-5minA:
undetectable		 4iqqC-5minA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM2_B_TOPB202_1
(DIHYDROFOLATE
REDUCTASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		5 / 12 PHE A  17
LEU A 372
VAL A 410
LEU A 419
ILE A 364
 None
 1.10A 4km2B-5minA:
undetectable		 4km2B-5minA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		5 / 12 ASN A 212
LEU A 149
LEU A 204
ASN A 203
GLY A 152
 None
 1.23A 4qckA-5minA:
0.0		 4qckA-5minA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		5 / 12 GLY A  81
GLY A  98
GLY A  78
ASN A  77
ALA A  83
 None
 0.90A 4uciA-5minA:
undetectable		 4uciA-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		5 / 12 GLY A  81
GLY A  98
GLY A  78
ASN A  77
ALA A  83
 None
 0.90A 4uciB-5minA:
undetectable		 4uciB-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		5 / 12 GLY A  81
GLY A  98
GLY A  78
ASN A  77
ALA A  83
 None
 0.88A 4uckA-5minA:
undetectable		 4uckA-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 6 ALA A 269
THR A 323
THR A 326
TYR A 271
 CA  A 502 (-4.6A)
None
None
None
 1.27A 4w5rA-5minA:
undetectable		 4w5rA-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		5 / 12 SER A  97
VAL A 132
LEU A 149
LEU A 204
ALA A  83
 None
 1.11A 4x1kA-5minA:
undetectable
4x1kB-5minA:
undetectable		 4x1kA-5minA:
11.14
4x1kB-5minA:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 6 ALA A 269
THR A 323
THR A 326
TYR A 271
 CA  A 502 (-4.6A)
None
None
None
 1.30A 4z4cA-5minA:
undetectable		 4z4cA-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 6 ALA A 269
THR A 323
THR A 326
TYR A 271
 CA  A 502 (-4.6A)
None
None
None
 1.28A 4z4fA-5minA:
undetectable		 4z4fA-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 5 ALA A 269
THR A 323
THR A 326
TYR A 271
 CA  A 502 (-4.6A)
None
None
None
 1.28A 4z4gA-5minA:
undetectable		 4z4gA-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 6 ALA A 269
THR A 323
THR A 326
TYR A 271
 CA  A 502 (-4.6A)
None
None
None
 1.26A 4z4iA-5minA:
undetectable		 4z4iA-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		3 / 3 LYS A  28
ARG A 408
HIS A  30
 None
 1.09A 4zbrA-5minA:
undetectable		 4zbrA-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 5 VAL A 349
VAL A 380
GLY A 379
PHE A   9
 None
 0.94A 5d4nA-5minA:
undetectable
5d4nC-5minA:
undetectable		 5d4nA-5minA:
undetectable
5d4nC-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		5 / 12 TYR A 420
SER A 413
VAL A 418
LEU A 372
TYR A 355
 None
 1.29A 5g6sB-5minA:
undetectable
5g6sC-5minA:
undetectable		 5g6sB-5minA:
19.02
5g6sC-5minA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 7 ILE A  94
LEU A 149
GLY A  81
PHE A  82
 None
 0.69A 5nooA-5minA:
undetectable		 5nooA-5minA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 7 ILE A  94
LEU A 149
GLY A  81
PHE A  82
 None
 0.74A 5nooB-5minA:
undetectable		 5nooB-5minA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 7 ILE A  94
LEU A 149
GLY A  81
PHE A  82
 None
 0.69A 5x5qC-5minA:
undetectable		 5x5qC-5minA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 8 ILE A  94
LEU A 149
GLY A  81
PHE A  82
 None
 0.73A 5x5qD-5minA:
undetectable		 5x5qD-5minA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 8 ILE A  94
LEU A 149
GLY A  81
PHE A  82
 None
 0.73A 5x5qF-5minA:
undetectable		 5x5qF-5minA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B
(Acinetobacter
calcoaceticus) 		4 / 6 PRO A 414
TRP A  34
ILE A 411
TYR A 420
 None
 1.13A 6gqiA-5minA:
undetectable		 6gqiA-5minA:
undetectable