SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5miy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 5miy E3 UBIQUITIN LIGASE
RAVN
(Legionella
pneumophila) 		5 / 9 PHE A  91
THR A  19
VAL A  21
LEU A  71
ILE A  33
 None
 0.96A 3tbgD-5miyA:
undetectable		 3tbgD-5miyA:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 5miy E3 UBIQUITIN LIGASE
RAVN
(Legionella
pneumophila) 		4 / 5 THR A  48
THR A  49
ASP A  46
TYR A  22
 None
 1.13A 4oltA-5miyA:
undetectable		 4oltA-5miyA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 5miy E3 UBIQUITIN LIGASE
RAVN
(Legionella
pneumophila) 		4 / 5 THR A  48
THR A  49
ASP A  46
TYR A  22
 None
 1.13A 4oltB-5miyA:
undetectable		 4oltB-5miyA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 5miy E3 UBIQUITIN LIGASE
RAVN
(Legionella
pneumophila) 		4 / 5 THR A  48
THR A  49
ASP A  46
TYR A  22
 None
 1.13A 4qwpA-5miyA:
undetectable		 4qwpA-5miyA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 5miy E3 UBIQUITIN LIGASE
RAVN
(Legionella
pneumophila) 		4 / 5 THR A  48
THR A  49
ASP A  46
TYR A  22
 None
 1.12A 4qwpB-5miyA:
undetectable		 4qwpB-5miyA:
16.05