SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mj3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G60_B_SAMB501_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 5mj3 INTERLEUKIN-12
SUBUNIT BETA
(Homo
sapiens) 		5 / 12 ILE A 233
PRO A 235
PHE A 140
THR A 261
TYR A 136
 None
 1.03A 1g60B-5mj3A:
undetectable		 1g60B-5mj3A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 5mj3 INTERLEUKIN-12
SUBUNIT BETA
(Homo
sapiens) 		4 / 6 TYR A 315
PHE A 227
SER A 226
ARG A 160
 None
 1.38A 2a3cA-5mj3A:
undetectable		 2a3cA-5mj3A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 5mj3 INTERLEUKIN-12
SUBUNIT BETA
(Homo
sapiens) 		3 / 3 LYS A 134
LYS A 234
PRO A 235
 None
 1.28A 4dv1L-5mj3A:
undetectable		 4dv1L-5mj3A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5mj3 INTERLEUKIN-12
SUBUNIT BETA
(Homo
sapiens) 		5 / 9 ASP A 312
SER A 317
TYR A 136
SER A 158
ILE A 208
 None
 1.41A 6giqA-5mj3A:
undetectable
6giqE-5mj3A:
undetectable
6giqI-5mj3A:
undetectable		 6giqA-5mj3A:
18.91
6giqE-5mj3A:
20.56
6giqI-5mj3A:
12.27