SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mje'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 5mje NANOBODY 8
(Lama
glama) 		3 / 3 TRP B  38
TYR B 102
LEU B   6
 None
 1.02A 1kxhA-5mjeB:
undetectable		 1kxhA-5mjeB:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 5mje NANOBODY 8
(Lama
glama) 		4 / 8 SER B   9
GLY B  10
ILE B  71
SER B  70
 None
 0.84A 5alcL-5mjeB:
13.8		 5alcL-5mjeB:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5mje CYTOTOXIC
TRANSLATIONAL
REPRESSOR OF
TOXIN-ANTITOXIN
STABILITY SYSTEM
(Vibrio
cholerae) 		4 / 7 GLU A  23
GLY A  61
SER A  63
GLY A  83
 None
 0.96A 5e26A-5mjeA:
undetectable
5e26B-5mjeA:
undetectable		 5e26A-5mjeA:
17.26
5e26B-5mjeA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5mje CYTOTOXIC
TRANSLATIONAL
REPRESSOR OF
TOXIN-ANTITOXIN
STABILITY SYSTEM
(Vibrio
cholerae) 		4 / 4 PHE A  11
ILE A  81
GLN A  28
ARG A  15
 None
 1.37A 5jm4B-5mjeA:
undetectable		 5jm4B-5mjeA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 5mje CYTOTOXIC
TRANSLATIONAL
REPRESSOR OF
TOXIN-ANTITOXIN
STABILITY SYSTEM
(Vibrio
cholerae) 		4 / 5 GLU A  23
GLY A  61
SER A  63
GLY A  83
 None
 0.89A 5kprA-5mjeA:
undetectable		 5kprA-5mjeA:
21.22