SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mjv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 5mjv CAPSID SUBUNIT VP3
(Parechovirus
A) 		3 / 3 MET B 236
LEU B 139
SER B 138
 None
 0.62A 1ee2A-5mjvB:
undetectable		 1ee2A-5mjvB:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 5mjv CAPSID SUBUNIT VP0
(Parechovirus
A) 		4 / 5 TYR C 154
PRO C 115
LEU C 272
ARG C 278
 None
 1.20A 1i2wA-5mjvC:
undetectable		 1i2wA-5mjvC:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_C_T44C128_1
(TRANSTHYRETIN)		 5mjv CAPSID SUBUNIT VP1
CAPSID SUBUNIT VP3
(Parechovirus
A) 		5 / 11 LEU A 159
LEU A  93
LEU A 199
SER A 200
VAL B  49
 None
 1.25A 1ictA-5mjvA:
undetectable
1ictC-5mjvA:
undetectable		 1ictA-5mjvA:
18.83
1ictC-5mjvA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 5mjv CAPSID SUBUNIT VP1
CAPSID SUBUNIT VP0
(Parechovirus
A;
Parechovirus
A) 		3 / 3 ASP A 134
ARG A 139
ASP C 288
 None
 0.85A 1vptA-5mjvA:
undetectable		 1vptA-5mjvA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5mjv CAPSID SUBUNIT VP3
CAPSID SUBUNIT VP0
(Parechovirus
A;
Parechovirus
A) 		5 / 12 SER B  85
PHE C 201
PRO C 250
THR B  87
ILE B 231
 None
 1.38A 2fj1A-5mjvB:
undetectable		 2fj1A-5mjvB:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 5mjv CAPSID SUBUNIT VP0
(Parechovirus
A) 		4 / 5 ILE C 253
LEU C 251
ASP C 262
ALA C 258
 None
 0.82A 2opxA-5mjvC:
undetectable		 2opxA-5mjvC:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5mjv CAPSID SUBUNIT VP0
(Parechovirus
A) 		5 / 12 VAL C 171
THR C 127
TRP C 126
VAL C 247
ALA C 183
 None
 1.18A 2x2iC-5mjvC:
undetectable		 2x2iC-5mjvC:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 5mjv CAPSID SUBUNIT VP0
CAPSID SUBUNIT VP1
(Parechovirus
A) 		3 / 3 TYR C 187
TYR A 109
GLY C 241
 None
 0.69A 3eteB-5mjvC:
undetectable
3eteD-5mjvC:
undetectable
3eteF-5mjvC:
undetectable		 3eteB-5mjvC:
19.43
3eteD-5mjvC:
19.43
3eteF-5mjvC:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 5mjv CAPSID SUBUNIT VP1
CAPSID SUBUNIT VP3
(Parechovirus
A;
Parechovirus
A) 		5 / 12 TYR A  49
GLU B 188
ILE B 189
THR B 190
ILE B 175
 None
 1.37A 3ndiA-5mjvA:
undetectable		 3ndiA-5mjvA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 5mjv CAPSID SUBUNIT VP3
CAPSID SUBUNIT VP0
(Parechovirus
A;
Parechovirus
A) 		5 / 12 ILE C 253
SER C 257
GLY C 256
THR C 255
SER B 222
 None
 1.43A 3r75A-5mjvC:
undetectable		 3r75A-5mjvC:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5mjv CAPSID SUBUNIT VP0
CAPSID SUBUNIT VP3
(Parechovirus
A) 		4 / 5 ARG C 132
LEU B 143
SER B 144
MET B  82
 None
 1.32A 4e1gA-5mjvC:
undetectable		 4e1gA-5mjvC:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5mjv CAPSID SUBUNIT VP1
CAPSID SUBUNIT VP0
(Parechovirus
A;
Parechovirus
A) 		3 / 3 ASP A 134
ARG A 139
ASP C 288
 None
 0.88A 4fzvA-5mjvA:
undetectable		 4fzvA-5mjvA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 5mjv CAPSID SUBUNIT VP3
(Parechovirus
A) 		3 / 3 TYR B 193
PHE B 243
ARG B 136
 None
 1.02A 4g19D-5mjvB:
undetectable		 4g19D-5mjvB:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5mjv CAPSID SUBUNIT VP1
CAPSID SUBUNIT VP3
(Parechovirus
A) 		5 / 12 ALA B 240
PHE B 128
PHE B 242
VAL A  68
VAL B 127
 None
 1.15A 4ib4A-5mjvB:
undetectable		 4ib4A-5mjvB:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5mjv CAPSID SUBUNIT VP0
(Parechovirus
A) 		3 / 3 ILE C 286
ASP C 239
ARG C 278
 None
 0.74A 4pstA-5mjvC:
undetectable		 4pstA-5mjvC:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 5mjv CAPSID SUBUNIT VP1
CAPSID SUBUNIT VP3
(Parechovirus
A;
Parechovirus
A) 		3 / 3 SER B 144
TYR B 146
ASP A  39
 None
 0.62A 4rp8C-5mjvB:
undetectable		 4rp8C-5mjvB:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2G_B_CTCB222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5mjv CAPSID SUBUNIT VP3
CAPSID SUBUNIT VP0
(Parechovirus
A;
Parechovirus
A) 		5 / 12 SER B  85
PHE C 201
PRO C 250
THR B  87
ILE B 231
 None
 1.35A 4v2gB-5mjvB:
undetectable		 4v2gB-5mjvB:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 5mjv CAPSID SUBUNIT VP0
CAPSID SUBUNIT VP1
CAPSID SUBUNIT VP3
(Parechovirus
A) 		5 / 10 GLY B 182
GLU C 216
ASP A  38
SER A  35
ALA A  36
 None
 1.32A 4wnuD-5mjvB:
undetectable		 4wnuD-5mjvB:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 5mjv CAPSID SUBUNIT VP0
(Parechovirus
A) 		4 / 8 GLY C 178
SER C 257
SER C 252
ASN C 176
 None
 1.03A 4ws1A-5mjvC:
undetectable		 4ws1A-5mjvC:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 5mjv CAPSID SUBUNIT VP0
CAPSID SUBUNIT VP1
(Parechovirus
A) 		5 / 12 THR C 205
GLU C 188
LEU A 210
LEU C 243
LEU A  42
 None
 1.25A 4xi3D-5mjvC:
undetectable		 4xi3D-5mjvC:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 5mjv CAPSID SUBUNIT VP1
CAPSID SUBUNIT VP3
(Parechovirus
A;
Parechovirus
A) 		5 / 12 GLY B 237
TYR A  49
ALA B  76
ASP B 239
ALA B 240
 None
 1.35A 4ymgB-5mjvB:
undetectable		 4ymgB-5mjvB:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPM_A_BO2A801_1
(LON PROTEASE)		 5mjv CAPSID SUBUNIT VP1
CAPSID SUBUNIT VP3
(Parechovirus
A) 		5 / 12 ALA B  63
THR B  62
LEU A 169
PRO A 209
ALA A 108
 None
 1.13A 4ypmA-5mjvB:
undetectable		 4ypmA-5mjvB:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_1
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 5mjv CAPSID SUBUNIT VP1
CAPSID SUBUNIT VP3
(Parechovirus
A;
Parechovirus
A) 		4 / 5 GLY B 137
ARG B 200
ASP B 239
MET A  56
 None
 1.34A 5ubbA-5mjvB:
undetectable		 5ubbA-5mjvB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 5mjv CAPSID SUBUNIT VP3
(Parechovirus
A) 		4 / 7 ARG B 200
ARG B 120
VAL B 129
GLY B 204
 None
 0.85A 5x80C-5mjvB:
undetectable
5x80D-5mjvB:
undetectable		 5x80C-5mjvB:
20.50
5x80D-5mjvB:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 5mjv CAPSID SUBUNIT VP1
CAPSID SUBUNIT VP3
(Parechovirus
A;
Parechovirus
A) 		4 / 7 PHE A  78
ALA A  75
GLY A 101
THR B  43
 None
 0.74A 5ybbB-5mjvA:
undetectable		 5ybbB-5mjvA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5mjv CAPSID SUBUNIT VP1
CAPSID SUBUNIT VP3
CAPSID SUBUNIT VP0
(Parechovirus
A;
Parechovirus
A;
Parechovirus
A) 		5 / 11 ASP B 184
SER A  35
GLY C 178
ALA C 258
ASN C 213
 None
 1.40A 6hu9A-5mjvB:
undetectable
6hu9E-5mjvB:
undetectable
6hu9I-5mjvB:
undetectable		 6hu9A-5mjvB:
22.30
6hu9E-5mjvB:
21.62
6hu9I-5mjvB:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5mjv CAPSID SUBUNIT VP1
CAPSID SUBUNIT VP3
CAPSID SUBUNIT VP0
(Parechovirus
A;
Parechovirus
A;
Parechovirus
A) 		5 / 10 ASP B 184
SER A  35
GLY C 178
ALA C 258
ASN C 213
 None
 1.38A 6hu9L-5mjvB:
undetectable
6hu9P-5mjvB:
undetectable
6hu9T-5mjvB:
undetectable		 6hu9L-5mjvB:
22.30
6hu9P-5mjvB:
21.62
6hu9T-5mjvB:
13.48