SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mkk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GMK_A_DVAA8_0 (GRAMICIDIN A)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	3 / 4	VAL B 17 TRP B 22 TRP B 14	None	1.28A	1gmkA-5mkkB: undetectable 1gmkB-5mkkB: undetectable	1gmkA-5mkkB: 3.48 1gmkB-5mkkB: 3.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GMK_C_DVAC8_0 (GRAMICIDIN A)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	3 / 4	VAL B 17 TRP B 22 TRP B 14	None	1.36A	1gmkC-5mkkB: undetectable 1gmkD-5mkkB: undetectable	1gmkC-5mkkB: 3.48 1gmkD-5mkkB: 3.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SA1_B_PODB700_1 (TUBULIN ALPHA CHAIN TUBULIN BETA CHAIN)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 12	VAL A 466 ALA A 506 LEU A 505 ALA A 475 ALA A 539	None	1.16A	1sa1A-5mkkA: undetectable 1sa1B-5mkkA: undetectable	1sa1A-5mkkA: 20.26 1sa1B-5mkkA: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SA1_D_PODD701_1 (TUBULIN ALPHA CHAIN TUBULIN BETA CHAIN)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 12	VAL A 466 ALA A 506 LEU A 505 ALA A 475 ALA A 539	None	1.17A	1sa1C-5mkkA: undetectable 1sa1D-5mkkA: undetectable	1sa1C-5mkkA: 20.26 1sa1D-5mkkA: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DDW_A_PXLA1003_1 (PYRIDOXINE KINASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	4 / 8	VAL A 358 VAL A 417 LEU A 360 ASP A 423	None	0.86A	2ddwA-5mkkA: undetectable	2ddwA-5mkkA: 19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F7A_B_BEZB1002_0 (HTH-TYPE TRANSCRIPTIONAL REGULATOR BENM)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 9	LEU B 367 LEU B 527 ILE B 529 LEU B 545 ILE B 543	None	1.19A	2f7aB-5mkkB: undetectable	2f7aB-5mkkB: 16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IDK_A_C2FA1410_0 (GLYCINE N-METHYLTRANSFERASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus; Thermus thermophilus)	5 / 11	LEU A 220 ARG B 121 TYR B 110 LEU B 102 HIS B 101	None	1.47A	2idkA-5mkkA: 1.8 2idkB-5mkkA: 1.7 2idkC-5mkkA: undetectable 2idkD-5mkkA: undetectable	2idkA-5mkkA: 19.54 2idkB-5mkkA: 19.54 2idkC-5mkkA: 19.54 2idkD-5mkkA: 19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JN3_A_JN3A131_2 (FATTY ACID-BINDING PROTEIN, LIVER)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	4 / 6	LEU B 261 GLN B 53 ILE A 54 PHE A 50	None	1.17A	2jn3A-5mkkB: undetectable	2jn3A-5mkkB: 15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OA1_B_ADNB2005_1 (TRYPTOPHAN HALOGENASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	4 / 7	GLY B 564 GLY B 563 VAL B 551 LEU A 602	None	0.80A	2oa1B-5mkkB: undetectable	2oa1B-5mkkB: 23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OAX_B_SNLB2001_2 (MINERALOCORTICOID RECEPTOR)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	4 / 4	LEU B 288 LEU B 295 MET B 253 MET B 176	None	1.39A	2oaxB-5mkkB: undetectable	2oaxB-5mkkB: 19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD4_A_CHDA801_0 (FERROCHELATASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 12	LEU B 227 LEU B 200 ARG B 229 LEU B 216 VAL B 211	None	1.21A	2qd4A-5mkkB: undetectable	2qd4A-5mkkB: 20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W3B_B_FOLB401_1 (DIHYDROFOLATE REDUCTASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus; Thermus thermophilus)	3 / 3	GLU A 236 GLN A 227 ARG B 411	None	0.91A	2w3bB-5mkkA: undetectable	2w3bB-5mkkA: 13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZBZ_A_VDXA501_1 (CYTOCHROME P450-SU1)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 11	VAL A 272 SER A 274 LEU A 293 VAL A 294 ALA B 283	None	1.22A	2zbzA-5mkkA: undetectable	2zbzA-5mkkA: 20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_A_CHDA151_0 (ILEAL BILE ACID-BINDING PROTEIN)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus; Thermus thermophilus)	4 / 7	TYR B 214 GLY A 437 VAL A 469 LEU A 456	None	0.91A	3elzA-5mkkB: undetectable	3elzA-5mkkB: 10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HKU_A_TORA300_1 (CARBONIC ANHYDRASE 2)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 12	ALA B 459 GLN B 479 VAL B 483 LEU B 468 THR B 466	None	1.26A	3hkuA-5mkkB: undetectable	3hkuA-5mkkB: 18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IW1_A_ASDA1223_1 (CYTOCHROME P450 CYP125)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 12	ILE B 65 VAL B 279 ILE A 54 VAL A 294 VAL A 297	None	1.10A	3iw1A-5mkkB: undetectable	3iw1A-5mkkB: 21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LS4_H_TCIH220_1 (HEAVY CHAIN OF ANTIBODY FAB FRAGMENT)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 10	VAL A 402 TYR A 410 GLY A 398 VAL A 375 GLY A 571	None None SO4 A 701 (-3.1A) None None	1.33A	3ls4H-5mkkA: undetectable	3ls4H-5mkkA: 16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S3O_A_DLUA399_1 (PFV INTEGRASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	4 / 7	ASP B 500 ASP B 499 PRO B 418 ARG B 107	None	1.24A	3s3oA-5mkkB: undetectable	3s3oA-5mkkB: 21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SOA_A_DB8A445_1 (CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE II SUBUNIT ALPHA WITH A BETA 7 LINKER)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	4 / 6	LEU A 113 VAL A 137 MET A 134 PHE B 205	None	1.13A	3soaA-5mkkA: undetectable	3soaA-5mkkA: 21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VAQ_A_ADNA401_2 (PUTATIVE ADENOSINE KINASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	4 / 4	LEU A 220 ALA A 215 PHE A 239 ASN B 123	None	1.47A	3vaqA-5mkkA: undetectable	3vaqA-5mkkA: 20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BLV_B_SAMB1281_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 12	HIS B 400 GLY B 337 GLY B 399 LEU B 496 GLY B 415	None	1.24A	4blvB-5mkkB: undetectable	4blvB-5mkkB: 19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_A_UEGA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 11	GLY A 448 ALA A 495 GLY A 491 VAL A 450 LYS A 502	None	1.28A	4c5lA-5mkkA: undetectable	4c5lA-5mkkA: 18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DA7_A_AC2A301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 10	GLY B 276 ALA B 283 VAL B 279 SER B 274 VAL B 49	None	1.13A	4da7A-5mkkB: undetectable	4da7A-5mkkB: 18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EK1_B_CAMB502_0 (CAMPHOR 5-MONOOXYGENASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus; Thermus thermophilus)	5 / 9	THR B 370 LEU A 595 VAL B 551 ASP B 546 VAL B 544	None	1.36A	4ek1B-5mkkB: undetectable	4ek1B-5mkkB: 22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ENH_A_FVXA602_1 (CHOLESTEROL 24-HYDROXYLASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 12	ILE B 428 ILE B 453 ALA B 451 ALA B 490 GLY B 435	None	1.11A	4enhA-5mkkB: undetectable	4enhA-5mkkB: 22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F8Y_A_VK3A202_1 (NADPH QUINONE OXIDOREDUCTASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	4 / 5	ARG B 209 TYR A 362 TYR A 410 LEU A 360	None	1.50A	4f8yA-5mkkB: undetectable 4f8yB-5mkkB: undetectable	4f8yA-5mkkB: 13.67 4f8yB-5mkkB: 13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F8Y_C_VK3C202_1 (NADPH QUINONE OXIDOREDUCTASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	4 / 7	ARG B 209 TYR A 362 TYR A 410 LEU A 360	None	1.38A	4f8yC-5mkkB: undetectable 4f8yD-5mkkB: undetectable	4f8yC-5mkkB: 13.67 4f8yD-5mkkB: 13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IKI_A_IMNA201_1 (TRANSTHYRETIN)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	3 / 3	LYS A 585 LEU A 582 ALA A 584	None	0.71A	4ikiA-5mkkA: undetectable	4ikiA-5mkkA: 12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J7U_A_YTZA802_1 (SEPIAPTERIN REDUCTASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 10	SER B 68 LEU B 40 PHE B 36 PRO B 42 GLN B 287	None	1.26A	4j7uA-5mkkB: 0.3	4j7uA-5mkkB: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J7U_D_YTZD802_1 (SEPIAPTERIN REDUCTASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	4 / 8	SER B 68 PHE B 36 PRO B 42 GLN B 287	None	1.07A	4j7uD-5mkkB: undetectable	4j7uD-5mkkB: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KJJ_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 12	ALA B 402 ALA B 382 ILE B 361 LEU B 527 ILE B 495	None	1.01A	4kjjA-5mkkB: undetectable	4kjjA-5mkkB: 14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M11_C_MXMC606_2 (PROSTAGLANDIN G/H SYNTHASE 2)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	3 / 3	LEU A 196 ARG A 199 MET A 321	None	0.82A	4m11C-5mkkA: undetectable	4m11C-5mkkA: 22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NJH_A_SAMA302_0 (7-CARBOXY-7-DEAZAGUA NINE SYNTHASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus; Thermus thermophilus)	5 / 12	THR A 395 THR B 373 GLU A 599 ASP A 522 GLN A 441	SO4 A 701 (-4.1A) SO4 B 601 (-4.4A) None None None	1.38A	4njhA-5mkkA: undetectable	4njhA-5mkkA: 15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NJK_A_SAMA302_0 (7-CARBOXY-7-DEAZAGUA NINE SYNTHASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus; Thermus thermophilus)	5 / 12	THR A 395 THR B 373 GLU A 599 ASP A 522 GLN A 441	SO4 A 701 (-4.1A) SO4 B 601 (-4.4A) None None None	1.38A	4njkA-5mkkA: undetectable	4njkA-5mkkA: 15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NJK_B_SAMB302_0 (7-CARBOXY-7-DEAZAGUA NINE SYNTHASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus; Thermus thermophilus)	5 / 12	THR A 395 THR B 373 GLU A 599 ASP A 522 GLN A 441	SO4 A 701 (-4.1A) SO4 B 601 (-4.4A) None None None	1.40A	4njkB-5mkkA: undetectable	4njkB-5mkkA: 15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OR0_A_NPSA602_1 (SERUM ALBUMIN)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 9	ALA A 390 ALA A 553 LEU A 556 LEU A 566 VAL A 567	None	1.16A	4or0A-5mkkA: 3.4	4or0A-5mkkA: 22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OR0_B_NPSB602_1 (SERUM ALBUMIN)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 9	ALA A 390 ALA A 553 LEU A 556 LEU A 566 VAL A 567	None	1.17A	4or0B-5mkkA: undetectable	4or0B-5mkkA: 22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P65_E_IPHE101_0 (INSULIN)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 11	LEU A 519 LEU A 540 ALA A 543 LEU A 504 LEU A 511	None	1.04A	4p65E-5mkkA: undetectable 4p65F-5mkkA: undetectable 4p65J-5mkkA: undetectable 4p65L-5mkkA: undetectable	4p65E-5mkkA: 7.95 4p65F-5mkkA: 4.65 4p65J-5mkkA: 4.65 4p65L-5mkkA: 4.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QTU_D_SAMD301_0 (PUTATIVE METHYLTRANSFERASE BUD23)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 12	GLY B 294 GLY B 296 MET B 299 ILE B 292 ARG B 80	None	1.15A	4qtuD-5mkkB: undetectable	4qtuD-5mkkB: 16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWP_A_GCSA301_1 (CHITOSANASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	3 / 3	TYR A 410 GLY A 123 PRO A 122	None	0.60A	4qwpA-5mkkA: undetectable	4qwpA-5mkkA: 17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R87_I_SPMI202_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	4 / 7	ASN B 431 GLU B 430 GLU B 465 TYR B 464	None	1.34A	4r87I-5mkkB: undetectable	4r87I-5mkkB: 16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UBE_A_2FAA401_1 (ADENOSINE KINASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 12	SER A 311 ASN A 315 PHE A 257 PHE A 260 GLN A 308	None	1.26A	4ubeA-5mkkA: undetectable	4ubeA-5mkkA: 21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4USW_A_ACTA1470_0 (ADENYLATE CYCLASE TYPE 10)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	4 / 6	LEU A 440 VAL A 439 ARG A 509 PHE A 444	None	0.91A	4uswA-5mkkA: undetectable	4uswA-5mkkA: 22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WG0_C_CHDC102_0 (NUCLEAR RECEPTOR COACTIVATOR 2)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	4 / 7	GLU A 501 LYS A 502 LEU A 505 LEU A 445	None	0.81A	4wg0B-5mkkA: undetectable 4wg0C-5mkkA: undetectable	4wg0B-5mkkA: 3.54 4wg0C-5mkkA: 3.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XZK_A_AG2A700_1 (PUTATIVE NAD(+)--ARGININE ADP-RIBOSYLTRANSFERA SE VIS)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	4 / 7	SER B 425 ARG B 487 PHE B 422 GLU A 218	None	1.20A	4xzkA-5mkkB: undetectable	4xzkA-5mkkB: 18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4C_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	4 / 6	TYR A 410 PRO A 412 LEU A 337 GLU A 336	None	1.30A	4z4cA-5mkkA: undetectable	4z4cA-5mkkA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5F1A_A_SALA601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	4 / 8	LEU B 165 LEU B 278 GLY B 264 ALA B 263	None	0.60A	5f1aA-5mkkB: undetectable	5f1aA-5mkkB: 20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M66_A_ADNA502_2 (ADENOSYLHOMOCYSTEINA SE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	4 / 4	GLN A 227 THR B 104 GLU A 236 LEU A 216	None	1.21A	5m66A-5mkkA: undetectable	5m66A-5mkkA: 23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MSD_A_BEZA1202_0 (CARBOXYLIC ACID REDUCTASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	4 / 5	HIS A 579 ILE A 559 SER A 578 ALA A 390	None	1.23A	5msdA-5mkkA: undetectable	5msdA-5mkkA: 21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N5D_B_SAMB303_0 (METHYLTRANSFERASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus; Thermus thermophilus)	5 / 12	LEU B 407 ALA B 408 VAL B 409 ILE B 497 GLU A 224	None	1.11A	5n5dB-5mkkB: undetectable	5n5dB-5mkkB: 18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ND2_B_TA1B601_1 (TUBULIN BETA-2B CHAIN)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 12	ALA B 30 SER B 34 ARG B 23 ARG B 142 LEU B 138	None	1.43A	5nd2B-5mkkB: undetectable	5nd2B-5mkkB: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWU_A_ACAA18_2 (WTFP-TAG,GP41)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	3 / 3	LEU A 242 LEU A 246 TRP A 250	None	0.92A	5nwuA-5mkkA: undetectable	5nwuA-5mkkA: 4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWV_A_ACAA18_1 (SCRFP-TAG,GP41)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 12	LEU B 560 GLU B 575 LEU B 572 GLU B 568 LEU A 595	None	1.19A	5nwvA-5mkkB: undetectable	5nwvA-5mkkB: 6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5SYF_B_TA1B502_1 (TUBULIN BETA CHAIN)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 12	ASP A 411 ALA A 407 SER A 404 ARG A 428 PRO A 122	None	1.32A	5syfB-5mkkA: undetectable	5syfB-5mkkA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCG_A_08YA602_2 (CYTOCHROME P450 3A4)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	3 / 3	ARG A 255 ARG B 23 ARG B 88	None	1.01A	5vcgA-5mkkA: 1.1	5vcgA-5mkkA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCG_A_08YA602_2 (CYTOCHROME P450 3A4)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	3 / 3	ARG B 81 ARG B 23 ARG B 88	None	0.98A	5vcgA-5mkkB: 0.5	5vcgA-5mkkB: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZV2_B_LEVB801_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 1)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	3 / 3	TYR B 231 LEU B 238 ASP B 184	None	0.86A	5zv2B-5mkkB: undetectable	5zv2B-5mkkB: 9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BXL_A_SAMA401_0 (2-(3-AMINO-3-CARBOXY PROPYL)HISTIDINE SYNTHASE)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 12	LEU A 504 GLY A 500 SER A 557 GLN A 537 ASP A 529	None	1.42A	6bxlA-5mkkA: undetectable	6bxlA-5mkkA: 21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BXM_A_SAMA402_0 (DIPHTHAMIDE BIOSYNTHESIS ENZYME DPH2)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	5 / 12	LEU A 504 GLY A 500 SER A 557 GLN A 537 ASP A 529	None	1.25A	6bxmA-5mkkA: undetectable	6bxmA-5mkkA: 20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6G1P_B_ACTB403_0 (ADP-RIBOSYLHYDROLASE LIKE 2)	5mkk	MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN (Thermus thermophilus)	3 / 3	PHE A 597 ARG A 594 GLN A 598	None	1.17A	6g1pB-5mkkA: undetectable	6g1pB-5mkkA: 21.66

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GMK_A_DVAA8_0","GRAMICIDIN A","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",3,"VAL B  17;TRP B  22;TRP B  14","None","1.28A","1gmkA-5mkkB:undetectable;1gmkB-5mkkB:undetectable","1gmkA-5mkkB:3.48;1gmkB-5mkkB:3.48"],["1GMK_C_DVAC8_0","GRAMICIDIN A","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",3,"VAL B  17;TRP B  22;TRP B  14","None","1.36A","1gmkC-5mkkB:undetectable;1gmkD-5mkkB:undetectable","1gmkC-5mkkB:3.48;1gmkD-5mkkB:3.48"],["1SA1_B_PODB700_1","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"VAL A 466;ALA A 506;LEU A 505;ALA A 475;ALA A 539","None","1.16A","1sa1A-5mkkA:undetectable;1sa1B-5mkkA:undetectable","1sa1A-5mkkA:20.26;1sa1B-5mkkA:20.73"],["1SA1_D_PODD701_1","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"VAL A 466;ALA A 506;LEU A 505;ALA A 475;ALA A 539","None","1.17A","1sa1C-5mkkA:undetectable;1sa1D-5mkkA:undetectable","1sa1C-5mkkA:20.26;1sa1D-5mkkA:20.73"],["2DDW_A_PXLA1003_1","PYRIDOXINE KINASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",4,"VAL A 358;VAL A 417;LEU A 360;ASP A 423","None","0.86A","2ddwA-5mkkA:undetectable","2ddwA-5mkkA:19.33"],["2F7A_B_BEZB1002_0","HTH-TYPE TRANSCRIPTIONAL REGULATOR BENM","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"LEU B 367;LEU B 527;ILE B 529;LEU B 545;ILE B 543","None","1.19A","2f7aB-5mkkB:undetectable","2f7aB-5mkkB:16.35"],["2IDK_A_C2FA1410_0","GLYCINE N-METHYLTRANSFERASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN;MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus;Thermus thermophilus",5,"LEU A 220;ARG B 121;TYR B 110;LEU B 102;HIS B 101","None","1.47A","2idkA-5mkkA:1.8;2idkB-5mkkA:1.7;2idkC-5mkkA:undetectable;2idkD-5mkkA:undetectable","2idkA-5mkkA:19.54;2idkB-5mkkA:19.54;2idkC-5mkkA:19.54;2idkD-5mkkA:19.54"],["2JN3_A_JN3A131_2","FATTY ACID-BINDING PROTEIN, LIVER","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",4,"LEU B 261;GLN B  53;ILE A  54;PHE A  50","None","1.17A","2jn3A-5mkkB:undetectable","2jn3A-5mkkB:15.87"],["2OA1_B_ADNB2005_1","TRYPTOPHAN HALOGENASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",4,"GLY B 564;GLY B 563;VAL B 551;LEU A 602","None","0.80A","2oa1B-5mkkB:undetectable","2oa1B-5mkkB:23.76"],["2OAX_B_SNLB2001_2","MINERALOCORTICOID RECEPTOR","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",4,"LEU B 288;LEU B 295;MET B 253;MET B 176","None","1.39A","2oaxB-5mkkB:undetectable","2oaxB-5mkkB:19.41"],["2QD4_A_CHDA801_0","FERROCHELATASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"LEU B 227;LEU B 200;ARG B 229;LEU B 216;VAL B 211","None","1.21A","2qd4A-5mkkB:undetectable","2qd4A-5mkkB:20.90"],["2W3B_B_FOLB401_1","DIHYDROFOLATE REDUCTASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN;MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus;Thermus thermophilus",3,"GLU A 236;GLN A 227;ARG B 411","None","0.91A","2w3bB-5mkkA:undetectable","2w3bB-5mkkA:13.65"],["2ZBZ_A_VDXA501_1","CYTOCHROME P450-SU1","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"VAL A 272;SER A 274;LEU A 293;VAL A 294;ALA B 283","None","1.22A","2zbzA-5mkkA:undetectable","2zbzA-5mkkA:20.75"],["3ELZ_A_CHDA151_0","ILEAL BILE ACID-BINDING PROTEIN","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN;MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus;Thermus thermophilus",4,"TYR B 214;GLY A 437;VAL A 469;LEU A 456","None","0.91A","3elzA-5mkkB:undetectable","3elzA-5mkkB:10.57"],["3HKU_A_TORA300_1","CARBONIC ANHYDRASE 2","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"ALA B 459;GLN B 479;VAL B 483;LEU B 468;THR B 466","None","1.26A","3hkuA-5mkkB:undetectable","3hkuA-5mkkB:18.35"],["3IW1_A_ASDA1223_1","CYTOCHROME P450 CYP125","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"ILE B  65;VAL B 279;ILE A  54;VAL A 294;VAL A 297","None","1.10A","3iw1A-5mkkB:undetectable","3iw1A-5mkkB:21.02"],["3LS4_H_TCIH220_1","HEAVY CHAIN OF ANTIBODY FAB FRAGMENT","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"VAL A 402;TYR A 410;GLY A 398;VAL A 375;GLY A 571","None;None;SO4 A 701 (-3.1A);None;None","1.33A","3ls4H-5mkkA:undetectable","3ls4H-5mkkA:16.40"],["3S3O_A_DLUA399_1","PFV INTEGRASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",4,"ASP B 500;ASP B 499;PRO B 418;ARG B 107","None","1.24A","3s3oA-5mkkB:undetectable","3s3oA-5mkkB:21.92"],["3SOA_A_DB8A445_1","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT ALPHA WITH A BETA 7 LINKER","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",4,"LEU A 113;VAL A 137;MET A 134;PHE B 205","None","1.13A","3soaA-5mkkA:undetectable","3soaA-5mkkA:21.75"],["3VAQ_A_ADNA401_2","PUTATIVE ADENOSINE KINASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",4,"LEU A 220;ALA A 215;PHE A 239;ASN B 123","None","1.47A","3vaqA-5mkkA:undetectable","3vaqA-5mkkA:20.10"],["4BLV_B_SAMB1281_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"HIS B 400;GLY B 337;GLY B 399;LEU B 496;GLY B 415","None","1.24A","4blvB-5mkkB:undetectable","4blvB-5mkkB:19.55"],["4C5L_A_UEGA300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"GLY A 448;ALA A 495;GLY A 491;VAL A 450;LYS A 502","None","1.28A","4c5lA-5mkkA:undetectable","4c5lA-5mkkA:18.12"],["4DA7_A_AC2A301_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"GLY B 276;ALA B 283;VAL B 279;SER B 274;VAL B  49","None","1.13A","4da7A-5mkkB:undetectable","4da7A-5mkkB:18.70"],["4EK1_B_CAMB502_0","CAMPHOR 5-MONOOXYGENASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN;MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus;Thermus thermophilus",5,"THR B 370;LEU A 595;VAL B 551;ASP B 546;VAL B 544","None","1.36A","4ek1B-5mkkB:undetectable","4ek1B-5mkkB:22.11"],["4ENH_A_FVXA602_1","CHOLESTEROL 24-HYDROXYLASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"ILE B 428;ILE B 453;ALA B 451;ALA B 490;GLY B 435","None","1.11A","4enhA-5mkkB:undetectable","4enhA-5mkkB:22.90"],["4F8Y_A_VK3A202_1","NADPH QUINONE OXIDOREDUCTASE;NADPH QUINONE OXIDOREDUCTASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",4,"ARG B 209;TYR A 362;TYR A 410;LEU A 360","None","1.50A","4f8yA-5mkkB:undetectable;4f8yB-5mkkB:undetectable","4f8yA-5mkkB:13.67;4f8yB-5mkkB:13.67"],["4F8Y_C_VK3C202_1","NADPH QUINONE OXIDOREDUCTASE;NADPH QUINONE OXIDOREDUCTASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",4,"ARG B 209;TYR A 362;TYR A 410;LEU A 360","None","1.38A","4f8yC-5mkkB:undetectable;4f8yD-5mkkB:undetectable","4f8yC-5mkkB:13.67;4f8yD-5mkkB:13.67"],["4IKI_A_IMNA201_1","TRANSTHYRETIN","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",3,"LYS A 585;LEU A 582;ALA A 584","None","0.71A","4ikiA-5mkkA:undetectable","4ikiA-5mkkA:12.78"],["4J7U_A_YTZA802_1","SEPIAPTERIN REDUCTASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"SER B  68;LEU B  40;PHE B  36;PRO B  42;GLN B 287","None","1.26A","4j7uA-5mkkB:0.3","4j7uA-5mkkB:21.53"],["4J7U_D_YTZD802_1","SEPIAPTERIN REDUCTASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",4,"SER B  68;PHE B  36;PRO B  42;GLN B 287","None","1.07A","4j7uD-5mkkB:undetectable","4j7uD-5mkkB:21.53"],["4KJJ_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"ALA B 402;ALA B 382;ILE B 361;LEU B 527;ILE B 495","None","1.01A","4kjjA-5mkkB:undetectable","4kjjA-5mkkB:14.39"],["4M11_C_MXMC606_2","PROSTAGLANDIN G\/H SYNTHASE 2","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",3,"LEU A 196;ARG A 199;MET A 321","None","0.82A","4m11C-5mkkA:undetectable","4m11C-5mkkA:22.15"],["4NJH_A_SAMA302_0","7-CARBOXY-7-DEAZAGUANINE SYNTHASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN;MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus;Thermus thermophilus",5,"THR A 395;THR B 373;GLU A 599;ASP A 522;GLN A 441","SO4 A 701 (-4.1A);SO4 B 601 (-4.4A);None;None;None","1.38A","4njhA-5mkkA:undetectable","4njhA-5mkkA:15.38"],["4NJK_A_SAMA302_0","7-CARBOXY-7-DEAZAGUANINE SYNTHASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN;MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus;Thermus thermophilus",5,"THR A 395;THR B 373;GLU A 599;ASP A 522;GLN A 441","SO4 A 701 (-4.1A);SO4 B 601 (-4.4A);None;None;None","1.38A","4njkA-5mkkA:undetectable","4njkA-5mkkA:15.38"],["4NJK_B_SAMB302_0","7-CARBOXY-7-DEAZAGUANINE SYNTHASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN;MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus;Thermus thermophilus",5,"THR A 395;THR B 373;GLU A 599;ASP A 522;GLN A 441","SO4 A 701 (-4.1A);SO4 B 601 (-4.4A);None;None;None","1.40A","4njkB-5mkkA:undetectable","4njkB-5mkkA:15.38"],["4OR0_A_NPSA602_1","SERUM ALBUMIN","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"ALA A 390;ALA A 553;LEU A 556;LEU A 566;VAL A 567","None","1.16A","4or0A-5mkkA:3.4","4or0A-5mkkA:22.19"],["4OR0_B_NPSB602_1","SERUM ALBUMIN","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"ALA A 390;ALA A 553;LEU A 556;LEU A 566;VAL A 567","None","1.17A","4or0B-5mkkA:undetectable","4or0B-5mkkA:22.19"],["4P65_E_IPHE101_0","INSULIN","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"LEU A 519;LEU A 540;ALA A 543;LEU A 504;LEU A 511","None","1.04A","4p65E-5mkkA:undetectable;4p65F-5mkkA:undetectable;4p65J-5mkkA:undetectable;4p65L-5mkkA:undetectable","4p65E-5mkkA:7.95;4p65F-5mkkA:4.65;4p65J-5mkkA:4.65;4p65L-5mkkA:4.65"],["4QTU_D_SAMD301_0","PUTATIVE METHYLTRANSFERASE BUD23","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"GLY B 294;GLY B 296;MET B 299;ILE B 292;ARG B  80","None","1.15A","4qtuD-5mkkB:undetectable","4qtuD-5mkkB:16.01"],["4QWP_A_GCSA301_1","CHITOSANASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",3,"TYR A 410;GLY A 123;PRO A 122","None","0.60A","4qwpA-5mkkA:undetectable","4qwpA-5mkkA:17.46"],["4R87_I_SPMI202_1","SPERMIDINE N1-ACETYLTRANSFERASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",4,"ASN B 431;GLU B 430;GLU B 465;TYR B 464","None","1.34A","4r87I-5mkkB:undetectable","4r87I-5mkkB:16.39"],["4UBE_A_2FAA401_1","ADENOSINE KINASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"SER A 311;ASN A 315;PHE A 257;PHE A 260;GLN A 308","None","1.26A","4ubeA-5mkkA:undetectable","4ubeA-5mkkA:21.65"],["4USW_A_ACTA1470_0","ADENYLATE CYCLASE TYPE 10","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",4,"LEU A 440;VAL A 439;ARG A 509;PHE A 444","None","0.91A","4uswA-5mkkA:undetectable","4uswA-5mkkA:22.14"],["4WG0_C_CHDC102_0","NUCLEAR RECEPTOR COACTIVATOR 2","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",4,"GLU A 501;LYS A 502;LEU A 505;LEU A 445","None","0.81A","4wg0B-5mkkA:undetectable;4wg0C-5mkkA:undetectable","4wg0B-5mkkA:3.54;4wg0C-5mkkA:3.54"],["4XZK_A_AG2A700_1","PUTATIVE NAD(+)--ARGININE ADP-RIBOSYLTRANSFERASE VIS","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",4,"SER B 425;ARG B 487;PHE B 422;GLU A 218","None","1.20A","4xzkA-5mkkB:undetectable","4xzkA-5mkkB:18.12"],["4Z4C_A_IPHA904_0","PROTEIN ARGONAUTE-2","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",4,"TYR A 410;PRO A 412;LEU A 337;GLU A 336","None","1.30A","4z4cA-5mkkA:undetectable","4z4cA-5mkkA:21.35"],["5F1A_A_SALA601_1","PROSTAGLANDIN G\/H SYNTHASE 2","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",4,"LEU B 165;LEU B 278;GLY B 264;ALA B 263","None","0.60A","5f1aA-5mkkB:undetectable","5f1aA-5mkkB:20.62"],["5M66_A_ADNA502_2","ADENOSYLHOMOCYSTEINASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",4,"GLN A 227;THR B 104;GLU A 236;LEU A 216","None","1.21A","5m66A-5mkkA:undetectable","5m66A-5mkkA:23.12"],["5MSD_A_BEZA1202_0","CARBOXYLIC ACID REDUCTASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",4,"HIS A 579;ILE A 559;SER A 578;ALA A 390","None","1.23A","5msdA-5mkkA:undetectable","5msdA-5mkkA:21.91"],["5N5D_B_SAMB303_0","METHYLTRANSFERASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN;MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus;Thermus thermophilus",5,"LEU B 407;ALA B 408;VAL B 409;ILE B 497;GLU A 224","None","1.11A","5n5dB-5mkkB:undetectable","5n5dB-5mkkB:18.65"],["5ND2_B_TA1B601_1","TUBULIN BETA-2B CHAIN","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"ALA B  30;SER B  34;ARG B  23;ARG B 142;LEU B 138","None","1.43A","5nd2B-5mkkB:undetectable","5nd2B-5mkkB:21.11"],["5NWU_A_ACAA18_2","WTFP-TAG,GP41","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",3,"LEU A 242;LEU A 246;TRP A 250","None","0.92A","5nwuA-5mkkA:undetectable","5nwuA-5mkkA:4.72"],["5NWV_A_ACAA18_1","SCRFP-TAG,GP41","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"LEU B 560;GLU B 575;LEU B 572;GLU B 568;LEU A 595","None","1.19A","5nwvA-5mkkB:undetectable","5nwvA-5mkkB:6.32"],["5SYF_B_TA1B502_1","TUBULIN BETA CHAIN","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"ASP A 411;ALA A 407;SER A 404;ARG A 428;PRO A 122","None","1.32A","5syfB-5mkkA:undetectable","5syfB-5mkkA:20.00"],["5VCG_A_08YA602_2","CYTOCHROME P450 3A4","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",3,"ARG A 255;ARG B  23;ARG B  88","None","1.01A","5vcgA-5mkkA:1.1","5vcgA-5mkkA:21.59"],["5VCG_A_08YA602_2","CYTOCHROME P450 3A4","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",3,"ARG B  81;ARG B  23;ARG B  88","None","0.98A","5vcgA-5mkkB:0.5","5vcgA-5mkkB:20.60"],["5ZV2_B_LEVB801_2","FIBROBLAST GROWTH FACTOR RECEPTOR 1","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",3,"TYR B 231;LEU B 238;ASP B 184","None","0.86A","5zv2B-5mkkB:undetectable","5zv2B-5mkkB:9.08"],["6BXL_A_SAMA401_0","2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"LEU A 504;GLY A 500;SER A 557;GLN A 537;ASP A 529","None","1.42A","6bxlA-5mkkA:undetectable","6bxlA-5mkkA:21.34"],["6BXM_A_SAMA402_0","DIPHTHAMIDE BIOSYNTHESIS ENZYME DPH2","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",5,"LEU A 504;GLY A 500;SER A 557;GLN A 537;ASP A 529","None","1.25A","6bxmA-5mkkA:undetectable","6bxmA-5mkkA:20.23"],["6G1P_B_ACTB403_0","ADP-RIBOSYLHYDROLASE LIKE 2","5mkk","MULTIDRUG RESISTANCE ABC TRANSPORTER ATP-BINDING AND PERMEASE PROTEIN","Thermus thermophilus",3,"PHE A 597;ARG A 594;GLN A 598","None","1.17A","6g1pB-5mkkA:undetectable","6g1pB-5mkkA:21.66"]]