SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mkm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 8 HIS A 103
HIS A 159
HIS A 157
HIS A 105
 OXY  A 403 ( 3.9A)
OXY  A 403 (-3.5A)
CU  A 402 ( 3.2A)
CU  A 402 (-3.2A)
 0.97A 1ei6D-5mkmA:
undetectable		 1ei6D-5mkmA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 4 HIS A 232
CYH A 289
HIS A 294
MET A 299
 CU  A 401 (-3.1A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.3A)
 0.50A 1oe1A-5mkmA:
21.4		 1oe1A-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 5 HIS A 232
CYH A 289
HIS A 294
MET A 299
 CU  A 401 (-3.1A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.3A)
 0.49A 1oe2A-5mkmA:
10.5		 1oe2A-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 4 HIS A 232
CYH A 289
HIS A 294
MET A 299
 CU  A 401 (-3.1A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.3A)
 0.53A 1oe3A-5mkmA:
21.5		 1oe3A-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_1
(VITAMIN D3 RECEPTOR)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 5 SER A 121
ARG A 129
HIS A 105
HIS A 157
 None
None
CU  A 402 (-3.2A)
CU  A 402 ( 3.2A)
 0.94A 1s19A-5mkmA:
undetectable		 1s19A-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 8 ARG A 181
HIS A 136
ARG A 245
VAL A 180
 None
 1.36A 1u1jA-5mkmA:
undetectable		 1u1jA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 4 HIS A 232
CYH A 289
HIS A 294
MET A 299
 CU  A 401 (-3.1A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.3A)
 0.48A 2fqdA-5mkmA:
17.9		 2fqdA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 4 HIS A 232
CYH A 289
HIS A 294
MET A 299
 CU  A 401 (-3.1A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.3A)
 0.45A 2fqeA-5mkmA:
17.9		 2fqeA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 4 HIS A 232
CYH A 289
HIS A 294
MET A 299
 CU  A 401 (-3.1A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.3A)
 0.47A 2fqfA-5mkmA:
17.9		 2fqfA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 4 HIS A 232
CYH A 289
HIS A 294
MET A 299
 CU  A 401 (-3.1A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.3A)
 0.49A 2fqgA-5mkmA:
17.9		 2fqgA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		5 / 12 ILE A 194
ALA A 214
VAL A 305
PHE A 234
HIS A 235
 None
 1.06A 2qo6A-5mkmA:
undetectable		 2qo6A-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 4 HIS A 157
HIS A 155
HIS A 105
HIS A 227
 CU  A 402 ( 3.2A)
None
CU  A 402 (-3.2A)
None
 1.12A 2wkoA-5mkmA:
undetectable		 2wkoA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 4 HIS A 232
CYH A 289
HIS A 294
MET A 299
 CU  A 401 (-3.1A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.3A)
 0.48A 2xxgA-5mkmA:
11.2		 2xxgA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 5 HIS A 232
CYH A 289
HIS A 294
MET A 299
 CU  A 401 (-3.1A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.3A)
 0.51A 2xxgC-5mkmA:
11.3		 2xxgC-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		3 / 3 HIS A 157
HIS A 105
HIS A 155
 CU  A 402 ( 3.2A)
CU  A 402 (-3.2A)
None
 0.72A 3ag4A-5mkmA:
undetectable		 3ag4A-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_2
(DIHYDROFOLATE
REDUCTASE)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 4 ILE A 194
PHE A 234
ILE A 222
THR A 226
 None
 1.03A 3ia4A-5mkmA:
undetectable		 3ia4A-5mkmA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		3 / 3 HIS A 288
HIS A 235
HIS A 237
 None
 0.80A 3mihA-5mkmA:
undetectable		 3mihA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		3 / 3 HIS A 288
HIS A 237
MET A 286
 None
 0.70A 3mihA-5mkmA:
undetectable		 3mihA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		5 / 12 TYR A 156
ILE A 194
PHE A 196
THR A 193
ILE A 222
 None
 1.34A 3ndiA-5mkmA:
undetectable		 3ndiA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 4 HIS A 232
CYH A 289
HIS A 294
MET A 299
 CU  A 401 (-3.1A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.3A)
 0.48A 4ef3A-5mkmA:
17.8		 4ef3A-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FEP_A_SAMA407_0
([FEFE] HYDROGENASE
MATURASE SUBUNIT
HYDE)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		5 / 12 TYR A  66
SER A 121
MET A  54
ILE A  80
TYR A 109
 None
 1.49A 5fepA-5mkmA:
undetectable		 5fepA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FES_A_SAMA408_0
([FEFE] HYDROGENASE
MATURASE SUBUNIT
HYDE)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		5 / 12 TYR A  66
SER A 121
MET A  54
ILE A  80
TYR A 109
 None
 1.50A 5fesA-5mkmA:
undetectable		 5fesA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 4 HIS A 105
HIS A 159
HIS A 103
HIS A 157
 CU  A 402 (-3.2A)
OXY  A 403 (-3.5A)
OXY  A 403 ( 3.9A)
CU  A 402 ( 3.2A)
 1.01A 5mhwA-5mkmA:
11.6		 5mhwA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 5 HIS A 290
HIS A 235
HIS A 288
HIS A 237
 None
 0.87A 5mhwA-5mkmA:
11.6		 5mhwA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 4 HIS A 105
HIS A 159
HIS A 103
HIS A 157
 CU  A 402 (-3.2A)
OXY  A 403 (-3.5A)
OXY  A 403 ( 3.9A)
CU  A 402 ( 3.2A)
 1.01A 5mhxA-5mkmA:
11.6		 5mhxA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 5 HIS A 290
HIS A 235
HIS A 288
HIS A 237
 None
 0.87A 5mhxA-5mkmA:
11.6		 5mhxA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 4 HIS A 105
HIS A 159
HIS A 103
HIS A 157
 CU  A 402 (-3.2A)
OXY  A 403 (-3.5A)
OXY  A 403 ( 3.9A)
CU  A 402 ( 3.2A)
 1.02A 5mhyA-5mkmA:
11.6		 5mhyA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 5 HIS A 290
HIS A 235
HIS A 288
HIS A 237
 None
 0.87A 5mhyA-5mkmA:
11.6		 5mhyA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 4 HIS A 105
HIS A 159
HIS A 103
HIS A 157
 CU  A 402 (-3.2A)
OXY  A 403 (-3.5A)
OXY  A 403 ( 3.9A)
CU  A 402 ( 3.2A)
 1.02A 5mhzA-5mkmA:
11.5		 5mhzA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 5 HIS A 290
HIS A 235
HIS A 288
HIS A 237
 None
 0.87A 5mhzA-5mkmA:
11.6		 5mhzA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 4 HIS A 105
HIS A 159
HIS A 103
HIS A 157
 CU  A 402 (-3.2A)
OXY  A 403 (-3.5A)
OXY  A 403 ( 3.9A)
CU  A 402 ( 3.2A)
 1.02A 5mi1A-5mkmA:
11.6		 5mi1A-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 5 HIS A 290
HIS A 235
HIS A 288
HIS A 237
 None
 0.87A 5mi1A-5mkmA:
11.6		 5mi1A-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 5 HIS A 290
HIS A 235
HIS A 288
HIS A 237
 None
 0.87A 5mi2A-5mkmA:
11.6		 5mi2A-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 5 HIS A 290
HIS A 235
HIS A 288
HIS A 237
 None
 0.87A 5miaA-5mkmA:
10.4		 5miaA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 5 HIS A 290
HIS A 235
HIS A 288
HIS A 237
 None
 0.87A 5mibA-5mkmA:
10.3		 5mibA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 5 HIS A 290
HIS A 235
HIS A 288
HIS A 237
 None
 0.87A 5micA-5mkmA:
11.6		 5micA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 4 HIS A 105
HIS A 159
HIS A 103
HIS A 157
 CU  A 402 (-3.2A)
OXY  A 403 (-3.5A)
OXY  A 403 ( 3.9A)
CU  A 402 ( 3.2A)
 1.02A 5midA-5mkmA:
11.6		 5midA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 5 HIS A 290
HIS A 235
HIS A 288
HIS A 237
 None
 0.87A 5midA-5mkmA:
11.6		 5midA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 5 HIS A 290
HIS A 235
HIS A 288
HIS A 237
 None
 0.87A 5mieA-5mkmA:
11.6		 5mieA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 5 HIS A 290
HIS A 235
HIS A 288
HIS A 237
 None
 0.86A 5migA-5mkmA:
10.3		 5migA-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 7 ALA A 214
THR A 215
GLN A 273
VAL A 220
 None
 0.93A 6cduA-5mkmA:
undetectable
6cduE-5mkmA:
undetectable		 6cduA-5mkmA:
undetectable
6cduE-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 6 GLN A 273
VAL A 220
ALA A 214
THR A 215
 None
 0.91A 6cduB-5mkmA:
undetectable
6cduC-5mkmA:
undetectable		 6cduB-5mkmA:
undetectable
6cduC-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 7 GLN A 273
VAL A 220
ALA A 214
THR A 215
 None
 0.90A 6cduC-5mkmA:
undetectable
6cduD-5mkmA:
undetectable		 6cduC-5mkmA:
undetectable
6cduD-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		4 / 7 GLN A 273
VAL A 220
ALA A 214
THR A 215
 None
 0.94A 6cduH-5mkmA:
undetectable
6cduI-5mkmA:
undetectable		 6cduH-5mkmA:
undetectable
6cduI-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		3 / 3 HIS A 157
HIS A 105
HIS A 155
 CU  A 402 ( 3.2A)
CU  A 402 (-3.2A)
None
 0.77A 6giqa-5mkmA:
undetectable		 6giqa-5mkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IEY_A_CLMA401_0
(ESTERASE)		 5mkm TWO-DOMAIN LACCASE
(Streptomyces
griseoflavus) 		5 / 11 HIS A 136
ASP A 108
GLY A 106
SER A 150
ALA A 148
 None
 1.17A 6ieyA-5mkmA:
undetectable
6ieyB-5mkmA:
undetectable		 6ieyA-5mkmA:
undetectable
6ieyB-5mkmA:
undetectable