SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mlg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZWP_A_NIMA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5mlg RENIN
(Rattus
norvegicus) 		4 / 5 LEU A 171
GLY A 174
TRP A 241
ASP A 188
 None
 1.49A 1zwpA-5mlgA:
undetectable		 1zwpA-5mlgA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 9 TYR A 325
LEU A 306
VAL A 288
GLY A 287
ILE A 282
 None
 1.16A 2a1oB-5mlgA:
undetectable		 2a1oB-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 5mlg RENIN
(Rattus
norvegicus) 		3 / 3 THR A 350
PRO A 352
PRO A 349
 None
 0.87A 2d55C-5mlgA:
undetectable		 2d55C-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_C_C41C1328_1
(RENIN)		 5mlg RENIN
(Rattus
norvegicus) 		8 / 12 ASP A  81
GLY A  83
SER A  84
PRO A 161
PHE A 167
VAL A 170
ASP A 266
GLY A 268
 None
 0.71A 2v0zC-5mlgA:
45.6		 2v0zC-5mlgA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_C_C41C1328_1
(RENIN)		 5mlg RENIN
(Rattus
norvegicus) 		6 / 12 ASP A  81
GLY A  83
VAL A 170
ASP A 266
GLY A 268
SER A 270
 None
 0.63A 2v0zC-5mlgA:
45.6		 2v0zC-5mlgA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_C_C41C1328_1
(RENIN)		 5mlg RENIN
(Rattus
norvegicus) 		6 / 12 VAL A 264
ASP A 266
GLY A 268
VAL A 355
ASP A  81
GLY A  83
 None
 0.75A 2v0zC-5mlgA:
45.6		 2v0zC-5mlgA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_1
(RENIN)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 12 ASP A  81
ALA A 165
PHE A 167
VAL A 170
GLY A 268
 None
 0.69A 2v0zO-5mlgA:
44.9		 2v0zO-5mlgA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_1
(RENIN)		 5mlg RENIN
(Rattus
norvegicus) 		6 / 12 ASP A  81
GLY A  83
PHE A 167
VAL A 170
ASP A 266
GLY A 268
 None
 0.55A 2v0zO-5mlgA:
44.9		 2v0zO-5mlgA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_1
(RENIN)		 5mlg RENIN
(Rattus
norvegicus) 		6 / 12 ASP A  81
GLY A  83
VAL A 170
ASP A 266
GLY A 268
SER A 270
 None
 0.61A 2v0zO-5mlgA:
44.9		 2v0zO-5mlgA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_1
(RENIN)		 5mlg RENIN
(Rattus
norvegicus) 		6 / 12 ASP A  81
GLY A 268
VAL A 170
ASP A 266
GLY A  83
ILE A 361
 None
 1.45A 2v0zO-5mlgA:
44.9		 2v0zO-5mlgA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_1
(RENIN)		 5mlg RENIN
(Rattus
norvegicus) 		6 / 12 VAL A 264
ASP A 266
GLY A 268
VAL A 355
ASP A  81
GLY A  83
 None
 0.73A 2v0zO-5mlgA:
44.9		 2v0zO-5mlgA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5mlg RENIN
(Rattus
norvegicus) 		3 / 3 SER A 270
GLU A  24
ASP A  29
 None
 0.71A 2zulA-5mlgA:
undetectable		 2zulA-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 5mlg RENIN
(Rattus
norvegicus) 		6 / 12 ASP A  81
GLY A  83
LEU A  55
ASP A 266
SER A 270
SER A 273
 None
 1.46A 3d91A-5mlgA:
45.7		 3d91A-5mlgA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 12 ASP A  81
GLY A  83
PHE A 167
ASP A 266
SER A 273
 None
 0.61A 3d91A-5mlgA:
45.7		 3d91A-5mlgA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 12 ASP A  81
GLY A  83
ASP A 266
SER A 270
SER A 273
 None
 0.77A 3d91B-5mlgA:
45.7		 3d91B-5mlgA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 12 ASP A  81
GLY A  83
VAL A 170
ASP A 266
SER A 273
 None
 0.51A 3d91B-5mlgA:
45.7		 3d91B-5mlgA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5mlg RENIN
(Rattus
norvegicus) 		3 / 3 SER A 270
GLU A  24
ASP A  29
 None
 0.71A 3dmhA-5mlgA:
undetectable		 3dmhA-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 9 GLY A 169
VAL A  78
ILE A 124
VAL A 131
VAL A 154
 None
 1.42A 3fhjD-5mlgA:
undetectable		 3fhjD-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 9 GLY A 169
VAL A  78
ILE A 124
VAL A 131
VAL A 154
 None
 1.42A 3fhjF-5mlgA:
undetectable		 3fhjF-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 9 GLY A 169
VAL A  78
ILE A 124
VAL A 131
VAL A 154
 None
 1.46A 3fi0C-5mlgA:
undetectable		 3fi0C-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 9 GLY A 169
VAL A  78
ILE A 124
VAL A 131
VAL A 154
 None
 1.45A 3fi0D-5mlgA:
undetectable		 3fi0D-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 9 GLY A 169
VAL A  78
ILE A 124
VAL A 131
VAL A 154
 None
 1.45A 3fi0F-5mlgA:
undetectable		 3fi0F-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 9 GLY A 169
VAL A  78
ILE A 124
VAL A 131
VAL A 154
 None
 1.46A 3fi0H-5mlgA:
undetectable		 3fi0H-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 9 GLY A 169
VAL A  78
ILE A 124
VAL A 131
VAL A 154
 None
 1.45A 3fi0J-5mlgA:
undetectable		 3fi0J-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 9 GLY A 169
VAL A  78
ILE A 124
VAL A 131
VAL A 154
 None
 1.44A 3fi0L-5mlgA:
undetectable		 3fi0L-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 9 GLY A 169
VAL A  78
ILE A 124
VAL A 131
VAL A 154
 None
 1.48A 3fi0M-5mlgA:
undetectable		 3fi0M-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 9 GLY A 169
VAL A  78
ILE A 124
VAL A 131
VAL A 154
 None
 1.44A 3fi0N-5mlgA:
undetectable		 3fi0N-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 9 GLY A 169
VAL A  78
ILE A 124
VAL A 131
VAL A 154
 None
 1.45A 3fi0R-5mlgA:
undetectable		 3fi0R-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IIZ_A_SAMA1501_0
(BIOTIN SYNTHETASE,
PUTATIVE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 12 TYR A  58
GLN A 342
SER A 273
GLY A 357
ILE A 160
 None
 1.21A 3iizA-5mlgA:
undetectable		 3iizA-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 12 ILE A 184
VAL A 140
GLN A 149
MET A 173
ILE A  11
 None
 1.12A 3iw1A-5mlgA:
undetectable		 3iw1A-5mlgA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 5mlg RENIN
(Rattus
norvegicus) 		4 / 8 GLY A  83
SER A  84
ILE A 124
ASP A 266
 None
 0.41A 3pwwA-5mlgA:
36.3		 3pwwA-5mlgA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 5mlg RENIN
(Rattus
norvegicus) 		4 / 6 LEU A 255
LEU A 256
LEU A 341
LEU A 279
 None
 1.01A 3q1eA-5mlgA:
1.2
3q1eC-5mlgA:
1.1		 3q1eA-5mlgA:
27.43
3q1eC-5mlgA:
27.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 5mlg RENIN
(Rattus
norvegicus) 		4 / 6 LEU A 341
LEU A 279
LEU A 255
LEU A 256
 None
 1.03A 3q1eA-5mlgA:
1.2
3q1eC-5mlgA:
1.1		 3q1eA-5mlgA:
27.43
3q1eC-5mlgA:
27.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 5mlg RENIN
(Rattus
norvegicus) 		6 / 12 ILE A  79
ASP A  81
GLY A  83
GLY A 127
ASP A 266
THR A 269
 None
 0.82A 3q70A-5mlgA:
9.6		 3q70A-5mlgA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 5mlg RENIN
(Rattus
norvegicus) 		6 / 12 ILE A  79
ASP A  81
GLY A  83
SER A 128
ASP A 266
THR A 269
 None
 0.74A 3q70A-5mlgA:
9.6		 3q70A-5mlgA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 12 ILE A  79
ASP A  81
GLY A  83
ILE A 124
ASP A 266
 None
 0.43A 3tneA-5mlgA:
34.8		 3tneA-5mlgA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 12 ILE A  79
ASP A  81
GLY A  83
ILE A 124
ASP A 266
 None
 0.43A 3tneB-5mlgA:
34.7		 3tneB-5mlgA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ8_A_TOPA2001_1
(DIHYDROFOLATE
REDUCTASE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 9 ALA A 263
PHE A 311
SER A 278
ILE A 282
ILE A 272
 None
 1.11A 3tq8A-5mlgA:
undetectable		 3tq8A-5mlgA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 12 TYR A  58
GLY A 172
GLY A  83
ILE A  79
ALA A 179
 None
 1.11A 4a6dA-5mlgA:
undetectable		 4a6dA-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 12 ASN A  57
ILE A 346
ASP A 345
GLY A 343
ASN A 294
 None
 1.37A 4djfA-5mlgA:
undetectable		 4djfA-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JXC_A_SAMA402_0
(FEFE-HYDROGENASE
MATURASE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 12 TYR A  58
GLN A 342
SER A 273
GLY A 357
ILE A 160
 None
 1.21A 4jxcA-5mlgA:
undetectable		 4jxcA-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 11 PHE A  40
SER A 128
GLY A 129
ILE A 243
LEU A 313
 None
 1.01A 4kt0A-5mlgA:
undetectable
4kt0J-5mlgA:
undetectable		 4kt0A-5mlgA:
7.46
4kt0J-5mlgA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5mlg RENIN
(Rattus
norvegicus) 		4 / 6 PHE A  80
MET A 173
ILE A  11
VAL A 140
 None
 1.13A 4mk4B-5mlgA:
undetectable		 4mk4B-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 5mlg RENIN
(Rattus
norvegicus) 		3 / 3 ASP A 266
ASP A  81
ASN A  86
 None
 0.66A 4q5mA-5mlgA:
9.9		 4q5mA-5mlgA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 5mlg RENIN
(Rattus
norvegicus) 		4 / 6 ALA A 263
GLN A 242
LEU A 356
LEU A  55
 None
 1.13A 4xoyA-5mlgA:
undetectable		 4xoyA-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FEP_A_SAMA407_0
([FEFE] HYDROGENASE
MATURASE SUBUNIT
HYDE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 12 TYR A  58
GLN A 342
SER A 273
GLY A 357
ILE A 160
 None
 1.22A 5fepA-5mlgA:
undetectable		 5fepA-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FES_A_SAMA408_0
([FEFE] HYDROGENASE
MATURASE SUBUNIT
HYDE)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 12 TYR A  58
GLN A 342
SER A 273
GLY A 357
ILE A 160
 None
 1.22A 5fesA-5mlgA:
undetectable		 5fesA-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5mlg RENIN
(Rattus
norvegicus) 		4 / 5 ILE A  67
ILE A 190
HIS A 189
VAL A 186
 None
 0.92A 5jmnA-5mlgA:
undetectable		 5jmnA-5mlgA:
6.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 5mlg RENIN
(Rattus
norvegicus) 		3 / 3 SER A 206
TYR A 205
TYR A 204
 None
 0.78A 5lakA-5mlgA:
undetectable
5lakI-5mlgA:
undetectable		 5lakA-5mlgA:
undetectable
5lakI-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 5mlg RENIN
(Rattus
norvegicus) 		3 / 3 SER A 206
TYR A 205
TYR A 204
 None
 0.77A 5lakC-5mlgA:
undetectable
5lakJ-5mlgA:
undetectable		 5lakC-5mlgA:
undetectable
5lakJ-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5mlg RENIN
(Rattus
norvegicus) 		4 / 7 LEU A 286
PRO A 307
LEU A 339
TYR A 325
 None
 1.07A 5t7bA-5mlgA:
undetectable		 5t7bA-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 5mlg RENIN
(Rattus
norvegicus) 		5 / 12 TYR A  58
GLY A 172
ASP A  81
MET A 173
PHE A 201
 None
 1.14A 5yn6A-5mlgA:
undetectable		 5yn6A-5mlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5mlg RENIN
(Rattus
norvegicus) 		3 / 3 ASN A  86
VAL A 147
HIS A 189
 None
 0.86A 6a5yD-5mlgA:
undetectable		 6a5yD-5mlgA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 5mlg RENIN
(Rattus
norvegicus) 		4 / 7 GLY A 182
ASN A 118
GLU A 153
GLY A 152
 None
NAG  A 401 (-1.9A)
None
None
 0.97A 6n7fA-5mlgA:
undetectable		 6n7fA-5mlgA:
17.65