SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mll'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 5mll DNA PROCESSING CHAIN
A (DPRA)
(Helicobacter
pylori) 		5 / 12 LEU A 179
LEU A 195
SER A 167
SER A 163
VAL A 154
 None
 1.35A 1db1A-5mllA:
undetectable		 1db1A-5mllA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_1
(DIHYDROFOLATE
REDUCTASE)		 5mll DNA PROCESSING CHAIN
A (DPRA)
(Helicobacter
pylori) 		5 / 12 ILE A  76
ALA A  47
ARG A 143
PRO A 109
ASN A 112
 None
 1.39A 1u70A-5mllA:
undetectable		 1u70A-5mllA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5mll DNA PROCESSING CHAIN
A (DPRA)
(Helicobacter
pylori) 		5 / 9 THR A 192
VAL A  84
GLY A  50
VAL A 154
ILE A 155
 None
 1.30A 2a1oB-5mllA:
undetectable		 2a1oB-5mllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 5mll DNA PROCESSING CHAIN
A (DPRA)
(Helicobacter
pylori) 		4 / 5 ILE A  76
LEU A  69
ALA A  47
PHE A 210
 None
 1.05A 2opxA-5mllA:
2.2		 2opxA-5mllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 5mll DNA PROCESSING CHAIN
A (DPRA)
(Helicobacter
pylori) 		5 / 12 GLY A  50
ASN A 144
VAL A 147
GLY A  80
ILE A  86
 None
 0.96A 2qakB-5mllA:
undetectable		 2qakB-5mllA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 5mll DNA PROCESSING CHAIN
A (DPRA)
(Helicobacter
pylori) 		4 / 7 THR A  55
PRO A  56
SER A  58
GLU A 188
 None
 1.05A 2v2gA-5mllA:
undetectable
2v2gB-5mllA:
undetectable		 2v2gA-5mllA:
undetectable
2v2gB-5mllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 5mll DNA PROCESSING CHAIN
A (DPRA)
(Helicobacter
pylori) 		4 / 7 THR A  55
PRO A  56
SER A  58
GLU A 188
 None
 1.01A 2v2gA-5mllA:
undetectable
2v2gB-5mllA:
undetectable		 2v2gA-5mllA:
undetectable
2v2gB-5mllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 5mll DNA PROCESSING CHAIN
A (DPRA)
(Helicobacter
pylori) 		4 / 7 THR A  55
PRO A  56
SER A  58
GLU A 188
 None
 1.07A 2v2gC-5mllA:
undetectable
2v2gD-5mllA:
undetectable		 2v2gC-5mllA:
undetectable
2v2gD-5mllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 5mll DNA PROCESSING CHAIN
A (DPRA)
(Helicobacter
pylori) 		4 / 7 THR A  55
PRO A  56
SER A  58
GLU A 188
 None
 1.05A 2v2gC-5mllA:
undetectable
2v2gD-5mllA:
undetectable		 2v2gC-5mllA:
undetectable
2v2gD-5mllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 5mll DNA PROCESSING CHAIN
A (DPRA)
(Helicobacter
pylori) 		4 / 8 THR A  55
PRO A  56
SER A  58
GLU A 188
 None
 1.00A 2v32A-5mllA:
undetectable
2v32B-5mllA:
undetectable		 2v32A-5mllA:
undetectable
2v32B-5mllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 5mll DNA PROCESSING CHAIN
A (DPRA)
(Helicobacter
pylori) 		4 / 7 THR A  55
PRO A  56
SER A  58
GLU A 188
 None
 0.96A 2v41E-5mllA:
undetectable
2v41F-5mllA:
undetectable		 2v41E-5mllA:
undetectable
2v41F-5mllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 5mll DNA PROCESSING CHAIN
A (DPRA)
(Helicobacter
pylori) 		4 / 7 THR A  55
PRO A  56
SER A  58
GLU A 188
 None
 1.05A 2v41E-5mllA:
undetectable
2v41F-5mllA:
undetectable		 2v41E-5mllA:
undetectable
2v41F-5mllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_2
(HIV-1 PROTEASE)		 5mll DNA PROCESSING CHAIN
A (DPRA)
(Helicobacter
pylori) 		5 / 12 ALA A  88
ILE A  49
GLY A  79
VAL A  75
ILE A  76
 None
 1.10A 3mwsB-5mllA:
undetectable		 3mwsB-5mllA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_B_KKKB413_1
(FLAVOHEMOGLOBIN)		 5mll DNA PROCESSING CHAIN
A (DPRA)
(Helicobacter
pylori) 		5 / 12 ILE A 155
ALA A  88
LEU A 182
ILE A 119
GLY A  80
 None
 1.08A 3ozwB-5mllA:
4.0		 3ozwB-5mllA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 5mll DNA PROCESSING CHAIN
A (DPRA)
(Helicobacter
pylori) 		4 / 7 ASN A 144
LEU A 171
ARG A 170
GLY A 138
 None
 0.87A 4cp3A-5mllA:
undetectable
4cp3B-5mllA:
undetectable		 4cp3A-5mllA:
19.35
4cp3B-5mllA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 5mll DNA PROCESSING CHAIN
A (DPRA)
(Helicobacter
pylori) 		5 / 12 LEU A  99
GLY A  79
GLN A  89
LEU A 104
CYH A 102
 None
None
None
EDO  A 301 (-4.5A)
EDO  A 301 (-3.3A)
 1.05A 5uc3B-5mllA:
undetectable		 5uc3B-5mllA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 5mll DNA PROCESSING CHAIN
A (DPRA)
(Helicobacter
pylori) 		5 / 12 LEU A  99
GLY A  80
GLN A  89
LEU A 104
CYH A 102
 None
None
None
EDO  A 301 (-4.5A)
EDO  A 301 (-3.3A)
 1.05A 5uc3B-5mllA:
undetectable		 5uc3B-5mllA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 5mll DNA PROCESSING CHAIN
A (DPRA)
(Helicobacter
pylori) 		4 / 5 ARG A  67
ALA A  66
GLN A 208
ILE A 207
 None
 1.37A 6g9bA-5mllA:
undetectable
6g9bB-5mllA:
undetectable		 6g9bA-5mllA:
21.95
6g9bB-5mllA:
23.75