SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mlp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JTX_A_CVIA200_0 (HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION)	5mlp	UNCHARACTERIZED PROTEIN (Rickettsiella grylli)	5 / 12	TYR A 212 ILE A 213 GLU A 135 TYR A 138 ASN A 180	None	1.15A	1jtxA-5mlpA: undetectable	1jtxA-5mlpA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HZN_G_ACTG225_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	5mlp	UNCHARACTERIZED PROTEIN (Rickettsiella grylli)	3 / 3	PRO A 76 LEU A 77 GLN A 70	None	0.52A	3hznG-5mlpA: undetectable 3hznH-5mlpA: undetectable	3hznG-5mlpA: undetectable 3hznH-5mlpA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4USW_A_ACTA1470_0 (ADENYLATE CYCLASE TYPE 10)	5mlp	UNCHARACTERIZED PROTEIN (Rickettsiella grylli)	4 / 6	LEU A 25 LEU A 109 VAL A 110 PHE A 58	None	1.02A	4uswA-5mlpA: undetectable	4uswA-5mlpA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MUG_A_VIVA301_1 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	5mlp	UNCHARACTERIZED PROTEIN (Rickettsiella grylli)	3 / 3	SER A 98 SER A 101 PHE A 239	None	0.95A	5mugA-5mlpA: 2.1	5mugA-5mlpA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1JTX_A_CVIA200_0","HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION","5mlp","UNCHARACTERIZED PROTEIN","Rickettsiella grylli",5,"TYR A 212;ILE A 213;GLU A 135;TYR A 138;ASN A 180","None","1.15A","1jtxA-5mlpA:undetectable","1jtxA-5mlpA:undetectable"],["3HZN_G_ACTG225_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","5mlp","UNCHARACTERIZED PROTEIN","Rickettsiella grylli",3,"PRO A  76;LEU A  77;GLN A  70","None","0.52A","3hznG-5mlpA:undetectable;3hznH-5mlpA:undetectable","3hznG-5mlpA:undetectable;3hznH-5mlpA:undetectable"],["4USW_A_ACTA1470_0","ADENYLATE CYCLASE TYPE 10","5mlp","UNCHARACTERIZED PROTEIN","Rickettsiella grylli",4,"LEU A  25;LEU A 109;VAL A 110;PHE A  58","None","1.02A","4uswA-5mlpA:undetectable","4uswA-5mlpA:undetectable"],["5MUG_A_VIVA301_1","ALPHA-TOCOPHEROL TRANSFER PROTEIN","5mlp","UNCHARACTERIZED PROTEIN","Rickettsiella grylli",3,"SER A  98;SER A 101;PHE A 239","None","0.95A","5mugA-5mlpA:2.1","5mugA-5mlpA:undetectable"]]