SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mm7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)		 5mm7 -
(-) 		4 / 7 GLU K  91
ARG K  83
THR K 190
ALA K  88
 ANP  K 501 (-3.5A)
ANP  K 501 (-4.3A)
None
ANP  K 501 ( 4.2A)
 0.98A 1fo4B-5mm7K:
undetectable		 1fo4B-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5mm7 -
(-) 		5 / 12 ILE K 234
THR K 232
ALA K 290
GLY K 304
LEU K 244
 None
 0.98A 1rjdA-5mm7K:
undetectable		 1rjdA-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5mm7 -
(-) 		5 / 12 ILE K 234
THR K 232
ALA K 290
GLY K 304
LEU K 244
 None
 0.98A 1rjdB-5mm7K:
undetectable		 1rjdB-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5mm7 -
(-) 		5 / 12 ILE K 234
THR K 232
ALA K 290
GLY K 304
LEU K 244
 None
 0.99A 1rjdC-5mm7K:
undetectable		 1rjdC-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5mm7 -
(-) 		4 / 7 TYR K 398
THR K 176
THR K 417
VAL K 385
 None
 1.16A 1tv8A-5mm7K:
undetectable		 1tv8A-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5mm7 -
(-) 		4 / 8 TYR K 398
THR K 176
THR K 417
VAL K 385
 None
 1.17A 2fb2A-5mm7K:
undetectable		 2fb2A-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5mm7 -
(-) 		4 / 7 TYR K 398
THR K 176
THR K 417
VAL K 385
 None
 1.22A 2fb2B-5mm7K:
undetectable		 2fb2B-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 5mm7 -
(-) 		5 / 10 ILE K  78
PHE K 178
LEU K 389
VAL K 385
LEU K 411
 None
 1.29A 2w98A-5mm7K:
undetectable		 2w98A-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5mm7 -
(-) 		4 / 7 TYR K 173
CYH K 175
ILE K 165
SER K  76
 None
 1.13A 2xz5A-5mm7K:
undetectable
2xz5B-5mm7K:
undetectable		 2xz5A-5mm7K:
undetectable
2xz5B-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5mm7 -
(-) 		4 / 7 ILE K 165
SER K  76
TYR K 173
CYH K 175
 None
 1.13A 2xz5D-5mm7K:
undetectable
2xz5E-5mm7K:
undetectable		 2xz5D-5mm7K:
undetectable
2xz5E-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 5mm7 -
(-) 		4 / 8 ALA K 428
ILE K 430
ASN K 429
PRO K 105
 None
 0.97A 3fxrA-5mm7K:
undetectable		 3fxrA-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_C_PM6C1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5mm7 -
(-) 		4 / 6 GLU K  91
ARG K  83
THR K 190
ALA K  88
 ANP  K 501 (-3.5A)
ANP  K 501 (-4.3A)
None
ANP  K 501 ( 4.2A)
 0.87A 3ns1C-5mm7K:
undetectable		 3ns1C-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5mm7 -
(-) 		4 / 8 TYR K 439
THR K 381
TYR K 180
LEU K 403
 None
 1.03A 3wipG-5mm7K:
undetectable
3wipH-5mm7K:
undetectable		 3wipG-5mm7K:
undetectable
3wipH-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5mm7 -
(-) 		5 / 12 PHE K 144
ILE K 208
GLN K 108
ARG K 106
ILE K 420
 None
 1.33A 4djfA-5mm7K:
undetectable		 4djfA-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 5mm7 -
(-) 		5 / 12 ILE K 419
LEU K 437
VAL K 423
THR K 436
THR K 190
 None
 1.12A 5byjA-5mm7K:
undetectable		 5byjA-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 5mm7 -
(-) 		5 / 12 ILE K 419
LEU K 437
VAL K 423
THR K 436
THR K 190
 None
 1.25A 5bykA-5mm7K:
undetectable		 5bykA-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5mm7 -
(-) 		4 / 6 SER K 322
ARG K 242
GLU K 235
TYR K 237
 None
 1.11A 5x7pB-5mm7K:
undetectable		 5x7pB-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5mm7 -
(-) 		5 / 10 ILE K 419
LEU K 437
VAL K 423
THR K 436
THR K 190
 None
 1.18A 6b4yA-5mm7K:
undetectable		 6b4yA-5mm7K:
undetectable