SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mm8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 5mm8 SERINE PROTEASE SPLE
(Staphylococcus
aureus) 		4 / 7 PHE A 171
ASN A  37
ASN A 154
VAL A 159
 None
 1.34A 1wu8A-5mm8A:
undetectable
1wu8C-5mm8A:
undetectable		 1wu8A-5mm8A:
18.44
1wu8C-5mm8A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5mm8 SERINE PROTEASE SPLE
(Staphylococcus
aureus) 		3 / 3 LYS A 193
TYR A 187
PRO A 190
 None
 1.02A 2j9cC-5mm8A:
undetectable		 2j9cC-5mm8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 5mm8 SERINE PROTEASE SPLE
(Staphylococcus
aureus) 		4 / 4 SER A 155
GLY A 156
GLY A 172
GLY A 185
 None
 0.80A 3bogB-5mm8A:
undetectable
3bogD-5mm8A:
undetectable		 3bogB-5mm8A:
undetectable
3bogD-5mm8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 5mm8 SERINE PROTEASE SPLE
(Staphylococcus
aureus) 		4 / 7 SER A 115
ALA A 158
ILE A 104
ALA A 105
 None
 0.97A 6ma7A-5mm8A:
undetectable		 6ma7A-5mm8A:
16.25