SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mmh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		5 / 11 GLY A 154
HIS A 153
THR A 267
THR A 155
GLY A 150
 None
 1.09A 1c9sP-5mmhA:
undetectable
1c9sQ-5mmhA:
undetectable		 1c9sP-5mmhA:
17.67
1c9sQ-5mmhA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		5 / 11 GLY A 154
HIS A 153
THR A 267
THR A 155
GLY A 150
 None
 1.08A 1gtfQ-5mmhA:
undetectable
1gtfR-5mmhA:
undetectable		 1gtfQ-5mmhA:
17.67
1gtfR-5mmhA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_C_AG2C7004_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		4 / 6 ALA A 100
LEU A 113
LEU A 285
LEU A  96
 None
 0.97A 1mt1D-5mmhA:
undetectable
1mt1E-5mmhA:
undetectable		 1mt1D-5mmhA:
15.60
1mt1E-5mmhA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 154
HIS A 153
THR A 267
THR A 155
GLY A 150
 None
 1.08A 1utdE-5mmhA:
undetectable
1utdF-5mmhA:
undetectable		 1utdE-5mmhA:
17.67
1utdF-5mmhA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 154
HIS A 153
THR A 267
THR A 155
GLY A 150
 None
 1.09A 1utdH-5mmhA:
undetectable
1utdI-5mmhA:
undetectable		 1utdH-5mmhA:
17.67
1utdI-5mmhA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		5 / 11 GLY A 154
HIS A 153
THR A 267
THR A 155
GLY A 150
 None
 1.10A 1utdS-5mmhA:
undetectable
1utdT-5mmhA:
undetectable		 1utdS-5mmhA:
17.67
1utdT-5mmhA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		4 / 5 ILE A 123
LEU A 125
ASP A 142
ALA A 277
 None
 0.99A 2opxA-5mmhA:
undetectable		 2opxA-5mmhA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		5 / 12 MET A 241
SER A 221
THR A 257
PHE A 147
ALA A 194
 None
 1.19A 3nxuB-5mmhA:
undetectable		 3nxuB-5mmhA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 265
TRP A 152
THR A 155
 None
 1.47A 4bboB-5mmhA:
undetectable		 4bboB-5mmhA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		4 / 5 ALA A 240
ARG A 253
ALA A 163
GLU A 258
 None
 1.36A 5a06C-5mmhA:
undetectable
5a06D-5mmhA:
undetectable		 5a06C-5mmhA:
22.22
5a06D-5mmhA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		4 / 5 SER A 263
ARG A 294
GLY A 295
GLU A 298
 None
 1.12A 5btiA-5mmhA:
undetectable
5btiB-5mmhA:
undetectable		 5btiA-5mmhA:
19.84
5btiB-5mmhA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		4 / 5 SER A 263
ARG A 294
GLY A 295
GLU A 298
 None
 1.17A 5btiC-5mmhA:
undetectable
5btiD-5mmhA:
undetectable		 5btiC-5mmhA:
19.84
5btiD-5mmhA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 150
GLY A 154
HIS A 153
THR A 267
THR A 155
 None
 1.08A 5eevA-5mmhA:
undetectable
5eevB-5mmhA:
undetectable		 5eevA-5mmhA:
17.67
5eevB-5mmhA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 150
GLY A 154
HIS A 153
THR A 267
THR A 155
 None
 1.08A 5eewA-5mmhA:
undetectable
5eewB-5mmhA:
undetectable		 5eewA-5mmhA:
17.67
5eewB-5mmhA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 150
GLY A 154
HIS A 153
THR A 267
THR A 155
 None
 1.08A 5eexA-5mmhA:
undetectable
5eexB-5mmhA:
undetectable		 5eexA-5mmhA:
17.67
5eexB-5mmhA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 150
GLY A 154
HIS A 153
THR A 267
THR A 155
 None
 1.08A 5eeyA-5mmhA:
undetectable
5eeyB-5mmhA:
undetectable		 5eeyA-5mmhA:
17.67
5eeyB-5mmhA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 150
GLY A 154
HIS A 153
THR A 267
THR A 155
 None
 1.08A 5eezA-5mmhA:
undetectable
5eezB-5mmhA:
undetectable		 5eezA-5mmhA:
17.67
5eezB-5mmhA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 150
GLY A 154
HIS A 153
THR A 267
THR A 155
 None
 1.08A 5ef0A-5mmhA:
undetectable
5ef0B-5mmhA:
undetectable		 5ef0A-5mmhA:
17.67
5ef0B-5mmhA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 150
GLY A 154
HIS A 153
THR A 267
THR A 155
 None
 1.08A 5ef1A-5mmhA:
undetectable
5ef1B-5mmhA:
undetectable		 5ef1A-5mmhA:
17.67
5ef1B-5mmhA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 150
GLY A 154
HIS A 153
THR A 267
THR A 155
 None
 1.08A 5ef2A-5mmhA:
undetectable
5ef2B-5mmhA:
undetectable		 5ef2A-5mmhA:
17.67
5ef2B-5mmhA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 150
GLY A 154
HIS A 153
THR A 267
THR A 155
 None
 1.08A 5ef3A-5mmhA:
undetectable
5ef3B-5mmhA:
undetectable		 5ef3A-5mmhA:
17.67
5ef3B-5mmhA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR
(Pseudomonas
aeruginosa) 		4 / 4 GLY A  99
LEU A 141
VAL A 134
GLU A 139
 None
 1.40A 5yw0A-5mmhA:
undetectable		 5yw0A-5mmhA:
23.10