SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mmi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 5mmi 50S RIBOSOMAL
PROTEIN L34,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 LEU 3 108
HIS 3 112
LYS 3 141
 U  A 697 ( 4.4A)
U  A 476 ( 3.9A)
U  A 476 ( 3.4A)
 0.92A 1y7iA-5mmi3:
undetectable		 1y7iA-5mmi3:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5mmi PLASTID RIBOSOMAL
PROTEIN UL5C
(Spinacia
oleracea) 		5 / 10 LEU F 148
GLY F 146
LEU F 144
ILE F  87
PHE F 152
 None
 1.05A 2f8dA-5mmiF:
undetectable		 2f8dA-5mmiF:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5mmi PLASTID RIBOSOMAL
PROTEIN UL5C
(Spinacia
oleracea) 		5 / 10 LEU F 148
GLY F 146
LEU F 144
ILE F  87
PHE F 152
 None
 1.07A 2f8dB-5mmiF:
undetectable		 2f8dB-5mmiF:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5mmi PLASTID RIBOSOMAL
PROTEIN UL10C
(Spinacia
oleracea) 		4 / 7 GLN I 151
PHE I 150
LEU I 102
PHE I 134
 None
 0.91A 3ag2C-5mmiI:
undetectable		 3ag2C-5mmiI:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5mmi PLASTID RIBOSOMAL
PROTEIN UL10C
(Spinacia
oleracea) 		4 / 8 GLN I 151
PHE I 150
LEU I 102
PHE I 134
 None
 0.89A 3ag4C-5mmiI:
undetectable
3ag4J-5mmiI:
undetectable		 3ag4C-5mmiI:
21.69
3ag4J-5mmiI:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5mmi PLASTID RIBOSOMAL
PROTEIN UL5C
(Spinacia
oleracea) 		3 / 3 SER F 189
GLN F 188
PHE F 191
 None
 0.53A 3g4lC-5mmiF:
undetectable		 3g4lC-5mmiF:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5mmi PLASTID RIBOSOMAL
PROTEIN UL10C
(Spinacia
oleracea) 		5 / 12 LEU I  76
PHE I 134
ILE I 122
ALA I 113
ILE I 103
 None
 0.90A 4nkxC-5mmiI:
undetectable		 4nkxC-5mmiI:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5mmi PLASTID RIBOSOMAL
PROTEIN UL10C
(Spinacia
oleracea) 		5 / 12 LEU I  76
PHE I 134
ILE I 122
ALA I 113
ILE I 103
 None
 0.87A 4nkxD-5mmiI:
undetectable		 4nkxD-5mmiI:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 5mmi PLASTID RIBOSOMAL
PROTEIN UL10C
(Spinacia
oleracea) 		4 / 5 GLY I 163
ALA I 164
GLY I 172
PRO I 173
 None
 0.87A 4u9uA-5mmiI:
undetectable		 4u9uA-5mmiI:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 5mmi PLASTID RIBOSOMAL
PROTEIN UL10C
(Spinacia
oleracea) 		4 / 5 GLY I 163
ALA I 164
GLY I 172
PRO I 173
 None
 0.90A 4u9uB-5mmiI:
undetectable		 4u9uB-5mmiI:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_1
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 5mmi PLASTID RIBOSOMAL
PROTEIN UL5C
(Spinacia
oleracea) 		5 / 12 ALA F 202
VAL F 199
VAL F  89
GLU F 193
PHE F 152
 None
 1.47A 4zj8A-5mmiF:
undetectable		 4zj8A-5mmiF:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_1
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 5mmi PLASTID RIBOSOMAL
PROTEIN UL5C
(Spinacia
oleracea) 		5 / 12 ALA F 202
VAL F 199
VAL F 207
GLU F 193
PHE F 152
 None
 1.39A 4zj8A-5mmiF:
undetectable		 4zj8A-5mmiF:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 5mmi PLASTID RIBOSOMAL
PROTEIN UL5C
(Spinacia
oleracea) 		5 / 11 ILE F 157
GLY F 227
PHE F 175
LEU F 156
VAL F 183
 None
 1.27A 5hw4B-5mmiF:
undetectable		 5hw4B-5mmiF:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 5mmi PLASTID RIBOSOMAL
PROTEIN UL5C
(Spinacia
oleracea) 		4 / 7 PHE F  73
ALA F 213
GLY F 179
TYR F 181
 None
 0.87A 5uxdA-5mmiF:
undetectable		 5uxdA-5mmiF:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5mmi 50S RIBOSOMAL
PROTEIN L31
PLASTID RIBOSOMAL
PROTEIN UL5C
(Spinacia
oleracea;
Spinacia
oleracea) 		5 / 12 GLY F 227
ASP F 154
VAL 0  51
LEU 0  57
PHE 0  79
 None
 1.12A 5vooB-5mmiF:
undetectable		 5vooB-5mmiF:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 5mmi 50S RIBOSOMAL
PROTEIN L31
PLASTID RIBOSOMAL
PROTEIN UL5C
(Spinacia
oleracea;
Spinacia
oleracea) 		4 / 6 GLY F 115
THR 0  64
GLN 0  65
TYR 0  68
 None
 1.21A 6ag0A-5mmiF:
undetectable		 6ag0A-5mmiF:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 5mmi 50S RIBOSOMAL
PROTEIN L31
PLASTID RIBOSOMAL
PROTEIN UL5C
(Spinacia
oleracea;
Spinacia
oleracea) 		4 / 6 GLY F 115
THR 0  64
GLN 0  65
TYR 0  68
 None
 1.25A 6ag0C-5mmiF:
undetectable		 6ag0C-5mmiF:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 5mmi PLASTID RIBOSOMAL
PROTEIN UL5C
(Spinacia
oleracea) 		4 / 8 GLY F 139
LEU F 138
ALA F 123
LYS F 124
 U  A2329 ( 4.2A)
U  A2329 ( 4.4A)
U  A2329 ( 3.9A)
G  A2315 ( 3.2A)
 0.75A 6mdqA-5mmiF:
undetectable		 6mdqA-5mmiF:
13.28