SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mmj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 5mmj RIBOSOME-BINDING
FACTOR PSRP1,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 LEU y 116
VAL y  86
SER y  87
VAL y 114
LEU y  77
 None
 1.04A 1ie9A-5mmjy:
undetectable		 1ie9A-5mmjy:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 5mmj 30S RIBOSOMAL
PROTEIN S5,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 7 ASN e 155
ALA e 205
ALA e 204
ALA e 208
 None
 0.78A 3a2qA-5mmje:
undetectable		 3a2qA-5mmje:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5mmj RIBOSOME-BINDING
FACTOR PSRP1,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 THR y 135
VAL y 143
GLU y 111
 None
G  a 915 ( 4.6A)
None
 0.75A 3v4tA-5mmjy:
undetectable
3v4tD-5mmjy:
undetectable		 3v4tA-5mmjy:
22.92
3v4tD-5mmjy:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_A_SAMA401_0
(METHYLTRANSFERASE
MPPJ)		 5mmj 30S RIBOSOMAL
PROTEIN S5,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 GLY e 190
GLY e 188
ARG e 209
ALA e 279
ARG e 175
 None
None
None
None
A  a1028 ( 3.7A)
 1.18A 4kicA-5mmje:
undetectable		 4kicA-5mmje:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 5mmj 30S RIBOSOMAL
PROTEIN 3,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 6 ALA w 163
GLN w 162
LEU w 112
LEU w 114
 None
 1.16A 4xoyA-5mmjw:
undetectable		 4xoyA-5mmjw:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP3_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 5mmj 30S RIBOSOMAL
PROTEIN 3,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 6 ALA w 163
GLN w 162
LEU w 112
LEU w 114
 None
 1.26A 4xp3A-5mmjw:
undetectable		 4xp3A-5mmjw:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 5mmj 30S RIBOSOMAL
PROTEIN 3,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 SER w 127
LEU w 114
TRP w 150
VAL w 143
LEU w  99
 None
 1.43A 5jo9A-5mmjw:
undetectable		 5jo9A-5mmjw:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_1
(PROTEASE)		 5mmj 30S RIBOSOMAL
PROTEIN S5,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 ARG e 209
GLY e 192
ALA e 176
VAL e 156
VAL e 178
 None
 1.06A 6dh0B-5mmje:
undetectable		 6dh0B-5mmje:
17.14