SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mmx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 5mmx CSPYL1_ABA
(Citrus
sinensis) 		4 / 7 PHE B 100
LEU B 128
GLY B 136
ASP B  82
 None
 0.57A 1p2yA-5mmxB:
undetectable		 1p2yA-5mmxB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U72_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 5mmx CSPYL1_ABA
(Citrus
sinensis) 		5 / 12 LEU B  42
GLU B  38
PHE B 158
SER B 154
ASN B  71
 None
 1.09A 1u72A-5mmxB:
undetectable		 1u72A-5mmxB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 5mmx CSPYL1_ABA
(Citrus
sinensis) 		5 / 9 LEU B 197
VAL B 168
THR B 153
ILE B  77
VAL B  78
 None
 1.23A 2l8mA-5mmxB:
undetectable		 2l8mA-5mmxB:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 5mmx CSPYL1_ABA
(Citrus
sinensis) 		3 / 3 TYR B  52
VAL B 152
THR B  51
 None
 0.90A 2ygnA-5mmxB:
undetectable		 2ygnA-5mmxB:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF3_A_PAUA314_0
(PANTOTHENATE KINASE)		 5mmx CSPYL1_ABA
(Citrus
sinensis) 		4 / 6 ARG B  79
PHE B  81
MET B 102
PHE B 100
 None
 1.31A 3af3A-5mmxB:
undetectable		 3af3A-5mmxB:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5mmx CSPYL1_ABA
(Citrus
sinensis) 		4 / 7 PHE B  81
ASP B 126
VAL B 110
ARG B 108
 None
 1.10A 3p6hA-5mmxB:
undetectable		 3p6hA-5mmxB:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 5mmx CSPYL1_ABA
(Citrus
sinensis) 		4 / 4 VAL B 176
THR B 181
GLU B 182
GLU B 183
 None
 1.21A 4l78A-5mmxB:
undetectable		 4l78A-5mmxB:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 5mmx CSPYL1_ABA
(Citrus
sinensis) 		4 / 5 GLN B  85
HIS B  89
ILE B  91
ILE B 113
 None
 1.28A 5dnuA-5mmxB:
undetectable		 5dnuA-5mmxB:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 5mmx CSPYL1_ABA
(Citrus
sinensis) 		4 / 5 GLN B  85
HIS B  89
ILE B  91
ILE B 113
 None
 1.25A 5dnvA-5mmxB:
undetectable		 5dnvA-5mmxB:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_B_SAMB401_0
(O-METHYLTRANSFERASE)		 5mmx CSPYL1_ABA
(Citrus
sinensis) 		5 / 10 GLY B 136
ASP B 126
ARG B 124
SER B 106
PHE B  81
 None
 1.31A 6clxB-5mmxB:
undetectable		 6clxB-5mmxB:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5mmx CSPYL1_ABA
(Citrus
sinensis) 		4 / 6 GLY B 136
ASP B 126
SER B 138
ARG B 150
 None
 1.00A 6dwdA-5mmxB:
undetectable
6dwdC-5mmxB:
2.0		 6dwdA-5mmxB:
17.85
6dwdC-5mmxB:
17.85