SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mnd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 5mnd GRANULIN
(Cydia
pomonella
granulovirus) 		3 / 3 GLU A 195
ASN A 193
TRP A 102
 None
 1.14A 1r15C-5mndA:
undetectable		 1r15C-5mndA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 5mnd GRANULIN
(Cydia
pomonella
granulovirus) 		3 / 3 GLU A 195
ASN A 193
TRP A 102
 None
 1.19A 1r15D-5mndA:
undetectable		 1r15D-5mndA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 5mnd GRANULIN
(Cydia
pomonella
granulovirus) 		3 / 3 GLU A 195
ASN A 193
TRP A 102
 None
 1.17A 1r15E-5mndA:
undetectable		 1r15E-5mndA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 5mnd GRANULIN
(Cydia
pomonella
granulovirus) 		3 / 3 GLU A 195
ASN A 193
TRP A 102
 None
 1.19A 1r15F-5mndA:
undetectable		 1r15F-5mndA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5mnd GRANULIN
(Cydia
pomonella
granulovirus) 		4 / 5 ILE A 118
THR A 101
PHE A  97
PHE A 179
 None
 1.36A 3em0A-5mndA:
undetectable		 3em0A-5mndA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 5mnd GRANULIN
(Cydia
pomonella
granulovirus) 		5 / 12 PHE A 197
VAL A 201
ARG A  99
ALA A 180
GLU A  96
 None
 1.25A 4fiaA-5mndA:
undetectable		 4fiaA-5mndA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 5mnd GRANULIN
(Cydia
pomonella
granulovirus) 		5 / 12 PHE A 197
VAL A 201
ARG A  99
ALA A 180
GLU A  96
 None
 1.25A 4fiaA-5mndA:
undetectable		 4fiaA-5mndA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 5mnd GRANULIN
(Cydia
pomonella
granulovirus) 		4 / 7 TYR A 150
ALA A 143
ILE A 156
LEU A  88
 None
 0.95A 4uymB-5mndA:
undetectable		 4uymB-5mndA:
19.87