SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mob'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5mob SLPYL1_ABA
(Solanum
lycopersicum) 		5 / 10 GLY A 144
GLU A 178
SER A 146
ASP A 134
ILE A 135
 None
A8S  A 301 ( 4.6A)
None
None
None
 1.50A 1pw7A-5mobA:
undetectable		 1pw7A-5mobA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5mob SLPYL1_ABA
(Solanum
lycopersicum) 		4 / 5 ARG A 109
MET A 110
THR A 111
LEU A 136
 None
 1.25A 2eimJ-5mobA:
undetectable		 2eimJ-5mobA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5mob SLPYL1_ABA
(Solanum
lycopersicum) 		4 / 5 ARG A 109
MET A 110
THR A 111
LEU A 136
 None
 1.22A 2eimW-5mobA:
undetectable		 2eimW-5mobA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF3_A_PAUA314_0
(PANTOTHENATE KINASE)		 5mob SLPYL1_ABA
(Solanum
lycopersicum) 		4 / 6 ARG A  87
PHE A  89
MET A 110
PHE A 108
 None
 1.45A 3af3A-5mobA:
undetectable		 3af3A-5mobA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5mob SLPYL1_ABA
(Solanum
lycopersicum) 		4 / 5 ARG A 109
MET A 110
THR A 111
LEU A 136
 None
 1.42A 3ag1J-5mobA:
undetectable		 3ag1J-5mobA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5mob SLPYL1_ABA
(Solanum
lycopersicum) 		4 / 5 ARG A 109
MET A 110
THR A 111
LEU A 136
 None
 1.16A 3ag2J-5mobA:
undetectable		 3ag2J-5mobA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5mob SLPYL1_ABA
(Solanum
lycopersicum) 		4 / 5 ARG A 109
MET A 110
THR A 111
LEU A 136
 None
 1.34A 3ag4J-5mobA:
undetectable		 3ag4J-5mobA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 5mob SLPYL1_ABA
(Solanum
lycopersicum) 		4 / 4 VAL A 184
THR A 189
GLU A 190
GLU A 191
 None
SO4  A 302 (-4.1A)
None
None
 1.36A 4l78A-5mobA:
undetectable		 4l78A-5mobA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 5mob SLPYL1_ABA
(Solanum
lycopersicum) 		5 / 12 VAL A 160
SER A 179
HIS A  97
VAL A 118
CYH A 102
 None
 1.18A 5ergB-5mobA:
undetectable		 5ergB-5mobA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5mob SLPYL1_ABA
(Solanum
lycopersicum) 		4 / 5 ARG A 109
MET A 110
THR A 111
LEU A 136
 None
 1.30A 5w97J-5mobA:
undetectable		 5w97J-5mobA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5mob SLPYL1_ABA
(Solanum
lycopersicum) 		4 / 5 ARG A 109
MET A 110
THR A 111
LEU A 136
 None
 1.36A 5wauJ-5mobA:
undetectable		 5wauJ-5mobA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5mob SLPYL1_ABA
(Solanum
lycopersicum) 		4 / 5 ARG A 109
MET A 110
THR A 111
LEU A 136
 None
 1.22A 5x1fW-5mobA:
undetectable		 5x1fW-5mobA:
13.36