SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mog'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_1
(HMG-COA REDUCTASE)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		5 / 9 GLU A 513
CYH A 512
LEU A 538
LEU A 281
LEU A 289
 None
None
NRF  A 601 ( 4.5A)
NRF  A 601 (-4.6A)
None
 1.35A 1hwiA-5mogA:
2.6		 1hwiA-5mogA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOS_A_VIAA1_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		5 / 12 LEU A 298
PHE A 190
SER A 430
PHE A 274
ILE A 294
 None
 1.33A 1xosA-5mogA:
undetectable		 1xosA-5mogA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		5 / 12 GLY A 548
LEU A 546
GLY A 543
TYR A 532
PRO A 517
 None
 1.16A 1y4lA-5mogA:
undetectable		 1y4lA-5mogA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		4 / 4 GLY A 525
SER A 521
VAL A 370
LEU A 562
 None
 1.32A 1yajB-5mogA:
undetectable		 1yajB-5mogA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		4 / 6 LEU A 132
ILE A 325
VAL A 329
ALA A 120
 None
 0.89A 2j5mA-5mogA:
undetectable		 2j5mA-5mogA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		3 / 3 GLY A 315
ARG A 320
TYR A 442
 None
 0.74A 2opxA-5mogA:
2.4		 2opxA-5mogA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		5 / 11 ILE A 493
ALA A 491
LEU A 414
LEU A 476
SER A 436
 None
 1.08A 2w9sA-5mogA:
undetectable		 2w9sA-5mogA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		5 / 12 MET A 188
PHE A 190
ALA A 276
ALA A 280
MET A 310
 NRF  A 601 ( 4.2A)
None
None
NRF  A 601 (-3.4A)
NRF  A 601 ( 4.6A)
 1.30A 2x2nA-5mogA:
undetectable		 2x2nA-5mogA:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_C_X2NC1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		5 / 12 MET A 188
PHE A 190
ALA A 276
ALA A 280
MET A 310
 NRF  A 601 ( 4.2A)
None
None
NRF  A 601 (-3.4A)
NRF  A 601 ( 4.6A)
 1.34A 2x2nC-5mogA:
undetectable		 2x2nC-5mogA:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_B_TPFB490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		5 / 9 MET A 188
PHE A 190
ALA A 276
ALA A 280
MET A 310
 NRF  A 601 ( 4.2A)
None
None
NRF  A 601 (-3.4A)
NRF  A 601 ( 4.6A)
 1.28A 3l4dB-5mogA:
undetectable		 3l4dB-5mogA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_C_TPFC490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		5 / 9 MET A 188
PHE A 190
ALA A 276
ALA A 280
MET A 310
 NRF  A 601 ( 4.2A)
None
None
NRF  A 601 (-3.4A)
NRF  A 601 ( 4.6A)
 1.25A 3l4dC-5mogA:
undetectable		 3l4dC-5mogA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		5 / 12 ALA A 544
GLY A 116
LYS A 121
TYR A 122
LEU A 175
 FAD  A 600 (-3.2A)
None
None
None
None
 1.23A 3tm4A-5mogA:
4.4		 3tm4A-5mogA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		4 / 7 ALA A 144
ILE A 143
HIS A 159
GLY A 157
 None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.9A)
FAD  A 600 (-3.4A)
 0.77A 3v4tH-5mogA:
undetectable		 3v4tH-5mogA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		3 / 4 SER A 547
GLY A 141
GLU A 155
 None
FAD  A 600 (-3.2A)
None
 0.61A 4juoA-5mogA:
undetectable
4juoC-5mogA:
undetectable		 4juoA-5mogA:
23.64
4juoC-5mogA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI504_0
(RNA POLYMERASE
3D-POL)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		3 / 3 VAL A 329
GLY A 333
LYS A 129
 None
 0.74A 4k50I-5mogA:
undetectable		 4k50I-5mogA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		4 / 4 PHE A 204
ASP A 203
GLY A 214
SER A 187
 None
 1.20A 4xp9C-5mogA:
undetectable		 4xp9C-5mogA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		3 / 3 ASN A 221
SER A 200
ARG A 425
 None
 0.97A 5b2qA-5mogA:
undetectable		 5b2qA-5mogA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		4 / 4 SER A 540
ALA A 539
GLN A 292
THR A 508
 FAD  A 600 ( 4.3A)
None
None
None
 1.36A 5n0rA-5mogA:
undetectable		 5n0rA-5mogA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		4 / 4 SER A 540
ALA A 539
GLN A 292
THR A 508
 FAD  A 600 ( 4.3A)
None
None
None
 1.38A 5n0sA-5mogA:
undetectable		 5n0sA-5mogA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		4 / 5 SER A 540
ALA A 539
GLN A 292
THR A 508
 FAD  A 600 ( 4.3A)
None
None
None
 1.37A 5n0tA-5mogA:
undetectable		 5n0tA-5mogA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		4 / 4 SER A 540
ALA A 539
GLN A 292
THR A 508
 FAD  A 600 ( 4.3A)
None
None
None
 1.35A 5n0wA-5mogA:
undetectable		 5n0wA-5mogA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		4 / 5 SER A 540
ALA A 539
GLN A 292
THR A 508
 FAD  A 600 ( 4.3A)
None
None
None
 1.31A 5n0wB-5mogA:
undetectable		 5n0wB-5mogA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		4 / 4 SER A 540
ALA A 539
GLN A 292
THR A 508
 FAD  A 600 ( 4.3A)
None
None
None
 1.35A 5n0xA-5mogA:
undetectable		 5n0xA-5mogA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		4 / 5 SER A 540
ALA A 539
GLN A 292
THR A 508
 FAD  A 600 ( 4.3A)
None
None
None
 1.35A 5n4iA-5mogA:
undetectable		 5n4iA-5mogA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		4 / 7 GLY A 113
TYR A 165
ASP A 531
TYR A 532
 FAD  A 600 (-3.4A)
FAD  A 600 ( 4.5A)
FAD  A 600 (-3.7A)
None
 1.29A 5vlmG-5mogA:
undetectable		 5vlmG-5mogA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		4 / 7 ALA A 529
GLY A 116
GLY A 111
THR A 533
 None
None
FAD  A 600 (-3.2A)
None
 0.80A 5ybbB-5mogA:
undetectable		 5ybbB-5mogA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC
(Oryza
sativa) 		5 / 12 VAL A 138
GLU A 134
LEU A 313
ARG A 180
LEU A 117
 EPE  A 602 (-4.0A)
FAD  A 600 (-2.7A)
None
None
None
 1.23A 6ew0F-5mogA:
undetectable		 6ew0F-5mogA:
10.86