SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mp0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 5mp0 M7GPPPN-MRNA
HYDROLASE
(Homo
sapiens) 		4 / 6 ILE D 176
ARG D 233
ILE D 232
PHE D 126
 None
 1.07A 2q72A-5mp0D:
undetectable		 2q72A-5mp0D:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 5mp0 M7GPPPN-MRNA
HYDROLASE
(Homo
sapiens) 		4 / 7 ILE D 176
ARG D 233
ILE D 232
PHE D 126
 None
 1.07A 2qb4A-5mp0D:
undetectable		 2qb4A-5mp0D:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 5mp0 M7GPPPN-MRNA
HYDROLASE
(Homo
sapiens) 		5 / 12 LEU D 174
ILE D 202
ILE D 229
PRO D 234
ILE D 103
 None
 0.99A 3nu3A-5mp0D:
undetectable		 3nu3A-5mp0D:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 5mp0 M7GPPPN-MRNA
HYDROLASE
(Homo
sapiens) 		4 / 5 GLN D 116
ILE D 194
TYR D 118
GLU D 193
 None
 1.25A 4a99D-5mp0D:
undetectable		 4a99D-5mp0D:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5mp0 M7GPPPN-MRNA
HYDROLASE
(Homo
sapiens) 		5 / 12 ILE D 153
ALA D 102
GLY D 101
GLU D 144
GLY D 125
 None
 1.27A 4jlgA-5mp0D:
undetectable		 4jlgA-5mp0D:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 5mp0 M7GPPPN-MRNA
HYDROLASE
(Homo
sapiens) 		5 / 11 LEU D 174
ILE D 202
ILE D 229
PRO D 234
ILE D 103
 None
 0.94A 4rvjA-5mp0D:
undetectable		 4rvjA-5mp0D:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 5mp0 M7GPPPN-MRNA
HYDROLASE
(Homo
sapiens) 		5 / 11 LEU D 174
ILE D 202
ILE D 229
PRO D 234
ILE D 103
 None
 0.96A 4rvjC-5mp0D:
undetectable		 4rvjC-5mp0D:
22.62