SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mp4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 141
HIS A 184
SER A 177
LEU A 150
GLY A 117
 None
 1.19A 1jffB-5mp4A:
3.1		 1jffB-5mp4A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 9 THR A 123
GLY A 119
GLY A 163
SER A 160
GLY A 165
 None
 0.95A 1jhoA-5mp4A:
4.1		 1jhoA-5mp4A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 9 THR A 123
GLY A 119
GLY A 163
SER A 160
GLY A 165
 None
 0.95A 1jhrA-5mp4A:
3.3		 1jhrA-5mp4A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 9 THR A 123
GLY A 119
GLY A 163
SER A 160
GLY A 165
 None
 0.96A 1jhyA-5mp4A:
3.9		 1jhyA-5mp4A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 9 THR A 123
GLY A 119
GLY A 163
SER A 160
GLY A 165
 None
 0.96A 1l4nA-5mp4A:
undetectable		 1l4nA-5mp4A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 9 THR A 123
GLY A 119
GLY A 163
SER A 160
GLY A 165
 None
 0.96A 1l5kA-5mp4A:
undetectable		 1l5kA-5mp4A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 9 THR A 123
GLY A 119
GLY A 163
SER A 160
GLY A 165
 None
 0.97A 1l5lA-5mp4A:
undetectable		 1l5lA-5mp4A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 9 THR A 123
GLY A 119
GLY A 163
SER A 160
GLY A 165
 None
 0.97A 1l5mA-5mp4A:
undetectable		 1l5mA-5mp4A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 141
HIS A 184
SER A 177
LEU A 150
GLY A 117
 None
 1.19A 2hxfB-5mp4A:
3.0		 2hxfB-5mp4A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 141
HIS A 184
SER A 177
LEU A 150
GLY A 117
 None
 1.19A 2hxhB-5mp4A:
3.0		 2hxhB-5mp4A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 141
HIS A 184
SER A 177
LEU A 150
GLY A 117
 None
 1.19A 2p4nB-5mp4A:
2.9		 2p4nB-5mp4A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 141
HIS A 184
SER A 177
LEU A 150
GLY A 117
 None
 1.19A 2wbeB-5mp4A:
undetectable		 2wbeB-5mp4A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_C_ADNC601_1
(METHIONYL-TRNA
SYNTHETASE)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 11 ALA A  19
ALA A  17
GLY A 165
GLY A  75
ILE A   8
 None
 1.14A 2x1lC-5mp4A:
2.6		 2x1lC-5mp4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 9 VAL A   4
SER A  32
ARG A   3
ILE A 136
GLY A 109
 None
 1.20A 3cv9A-5mp4A:
undetectable		 3cv9A-5mp4A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 141
HIS A 184
SER A 177
LEU A 150
GLY A 117
 None
 1.19A 3dcoB-5mp4A:
2.9		 3dcoB-5mp4A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 141
HIS A 184
SER A 177
LEU A 150
GLY A 117
 None
 1.19A 3edlB-5mp4A:
3.1		 3edlB-5mp4A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 141
HIS A 184
SER A 177
LEU A 150
GLY A 117
 None
 1.17A 3iz0B-5mp4A:
2.9		 3iz0B-5mp4A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 109
VAL A 183
GLY A 188
ILE A  26
THR A  18
 None
 0.92A 3s56A-5mp4A:
undetectable		 3s56A-5mp4A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 THR A 166
GLN A 187
ALA A 122
GLY A 119
ASN A 126
 None
 1.00A 3v3oA-5mp4A:
3.6		 3v3oA-5mp4A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 8 ILE A   8
ILE A   6
GLN A 187
GLY A 188
 None
 0.79A 4acaC-5mp4A:
5.0		 4acaC-5mp4A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 9 THR A 123
GLY A 119
GLY A 163
SER A 160
GLY A 165
 None
 0.94A 4kqiA-5mp4A:
3.4		 4kqiA-5mp4A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 158
VAL A 156
GLY A 115
GLY A 117
ALA A 168
 None
None
None
None
PO4  A 201 ( 4.0A)
 0.97A 5x7fA-5mp4A:
undetectable		 5x7fA-5mp4A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 5mp4 PROTOPLAST SECRETED
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 6 GLU A 185
LYS A  23
GLU A  27
ALA A  28
 None
 0.92A 6an0A-5mp4A:
2.6		 6an0A-5mp4A:
18.67