SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mp7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5mp7 RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ILE A  93
ALA A  95
LEU A  97
LEU A  75
ILE A  82
 None
 1.29A 1g5yB-5mp7A:
undetectable		 1g5yB-5mp7A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 5mp7 RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE
(Mycolicibacteriu
m
smegmatis) 		4 / 8 THR A 225
ASP A 253
MET A 172
LEU A 192
 None
 0.91A 1lhvA-5mp7A:
undetectable		 1lhvA-5mp7A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 5mp7 RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE
(Mycolicibacteriu
m
smegmatis) 		5 / 9 GLY A  46
ILE A  48
ALA A  40
GLU A  77
ARG A  18
 None
 1.25A 1mrgA-5mp7A:
undetectable		 1mrgA-5mp7A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_B_CHCB201_2
(BILE ACID RECEPTOR)		 5mp7 RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 HIS A 138
ARG A 104
ILE A 301
HIS A 152
 None
 1.30A 1osvB-5mp7A:
undetectable		 1osvB-5mp7A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5mp7 RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 GLY A 194
VAL A 174
ALA A 189
SER A 191
 None
 1.00A 1p6kA-5mp7A:
undetectable		 1p6kA-5mp7A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 5mp7 RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE
(Mycolicibacteriu
m
smegmatis) 		5 / 9 ARG A 104
LEU A 228
ILE A 233
ALA A 258
GLY A 180
 None
 1.29A 2v0mB-5mp7A:
undetectable		 2v0mB-5mp7A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 5mp7 RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE
(Mycolicibacteriu
m
smegmatis) 		3 / 3 SER A  66
HIS A 138
ASP A 140
 None
 0.77A 2wa2B-5mp7A:
2.8		 2wa2B-5mp7A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4USW_A_ACTA1470_0
(ADENYLATE CYCLASE
TYPE 10)		 5mp7 RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A  64
LEU A  31
VAL A  27
PHE A  62
 None
 1.17A 4uswA-5mp7A:
undetectable		 4uswA-5mp7A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 5mp7 RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE
(Mycolicibacteriu
m
smegmatis) 		5 / 9 GLY A  46
ILE A  48
ALA A  40
GLU A  77
ARG A  18
 None
 1.27A 4yp2B-5mp7A:
undetectable		 4yp2B-5mp7A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 5mp7 RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE
(Mycolicibacteriu
m
smegmatis) 		5 / 9 GLY A  46
ILE A  48
ALA A  40
GLU A  77
ARG A  18
 None
 1.27A 5cf9B-5mp7A:
undetectable		 5cf9B-5mp7A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 5mp7 RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 192
THR A 259
ALA A 257
ILE A 255
ILE A 280
 None
 1.06A 5itzB-5mp7A:
undetectable		 5itzB-5mp7A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_ACTD305_0
(CARBONIC ANHYDRASE 4)		 5mp7 RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 ALA A 129
ALA A  95
ILE A  82
LEU A  79
 None
 0.55A 5jncD-5mp7A:
undetectable		 5jncD-5mp7A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 5mp7 RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE
(Mycolicibacteriu
m
smegmatis) 		3 / 3 THR A 297
GLU A 278
HIS A 166
 None
 0.88A 5xioA-5mp7A:
undetectable		 5xioA-5mp7A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5mp7 RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE
(Mycolicibacteriu
m
smegmatis) 		3 / 3 THR A 297
GLU A 278
HIS A 166
 None
 0.86A 5xiqB-5mp7A:
undetectable		 5xiqB-5mp7A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5mp7 RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE
(Mycolicibacteriu
m
smegmatis) 		3 / 3 THR A 297
GLU A 278
HIS A 166
 None
 0.92A 5xiqD-5mp7A:
undetectable		 5xiqD-5mp7A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 5mp7 RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE
(Mycolicibacteriu
m
smegmatis) 		3 / 3 LYS A 224
VAL A 173
ASP A 171
 None
 0.62A 6fgdA-5mp7A:
undetectable		 6fgdA-5mp7A:
24.43