SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mpi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 5mpi GRAINYHEAD-LIKE
PROTEIN 1 HOMOLOG
(Homo
sapiens) 		4 / 5 ALA A 355
ALA A 358
GLN A 317
VAL A 306
 None
 0.92A 2nyrB-5mpiA:
undetectable		 2nyrB-5mpiA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGG_A_CHDA211_0
(CMER)		 5mpi GRAINYHEAD-LIKE
PROTEIN 1 HOMOLOG
(Homo
sapiens) 		4 / 7 CYH A 335
PHE A 308
PHE A 382
PHE A 473
 None
 1.17A 3hggA-5mpiA:
undetectable		 3hggA-5mpiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5mpi GRAINYHEAD-LIKE
PROTEIN 1 HOMOLOG
(Homo
sapiens) 		3 / 3 PRO A 392
LEU A 391
GLN A 317
 None
 0.61A 4pevB-5mpiA:
undetectable		 4pevB-5mpiA:
10.07