SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mpm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 12 VAL A 725
ILE A 179
VAL A 159
ASN A  39
LEU A 119
None
1.26A 1fm4A-5mpmA:
undetectable
1fm4A-5mpmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
4 / 8 ARG A  35
LEU A  32
VAL A  18
GLY A  17
None
1.03A 1hrkB-5mpmA:
2.6
1hrkB-5mpmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
4 / 6 TRP A 551
VAL A 547
ILE A 548
LEU A 448
None
1.04A 1j96A-5mpmA:
undetectable
1j96A-5mpmA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 10 VAL A 976
ILE A 839
GLY A 840
GLY A 769
THR A 905
None
1.07A 1k6cA-5mpmA:
undetectable
1k6cA-5mpmA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
3 / 3 ASN A 380
ILE A 384
MET A 452
None
0.83A 2h42C-5mpmA:
undetectable
2h42C-5mpmA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_1
(PROTEASE)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 12 ALA A 745
ILE A 715
ILE A 332
THR A 700
ILE A 742
None
0.87A 2nmyA-5mpmA:
undetectable
2nmyA-5mpmA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 LEU A 356
ILE A 348
ARG A 334
GLU A 731
LEU A 734
None
None
None
K  A1005 (-2.9A)
None
1.33A 2v0mA-5mpmA:
undetectable
2v0mA-5mpmA:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 LEU A 356
PHE A 739
ARG A 334
GLU A 731
LEU A 734
None
None
None
K  A1005 (-2.9A)
None
1.44A 2v0mA-5mpmA:
undetectable
2v0mA-5mpmA:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 LEU A 356
ILE A 348
ARG A 334
GLU A 731
LEU A 734
None
None
None
K  A1005 (-2.9A)
None
1.25A 2v0mD-5mpmA:
2.4
2v0mD-5mpmA:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
4 / 7 LEU A 425
ASN A 469
GLU A 466
LEU A 462
None
1.26A 2w8yA-5mpmA:
undetectable
2w8yA-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
3 / 3 SER A  72
GLU A 309
ASP A 799
None
0.77A 2zulA-5mpmA:
undetectable
2zulA-5mpmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
3 / 3 THR A   6
PRO A 193
THR A   8
None
0.91A 316dC-5mpmA:
undetectable
316dC-5mpmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_2
(PROTEASE)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 9 ALA A 846
VAL A 976
ILE A 839
GLY A 769
THR A 905
None
1.24A 3el4B-5mpmA:
undetectable
3el4B-5mpmA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
4 / 7 THR A 166
LEU A  13
VAL A  18
THR A  22
None
1.01A 3fwiA-5mpmA:
undetectable
3fwiA-5mpmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 12 GLY A 354
ASN A 359
ILE A 742
ASP A 737
LEU A 734
MG  A1004 ( 4.2A)
None
None
None
None
1.00A 3ihtA-5mpmA:
undetectable
3ihtA-5mpmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 ASP A 799
SER A 766
LEU A  65
ILE A  94
GLU A 309
None
None
CZA  A1002 (-4.1A)
None
None
1.33A 3ko0A-5mpmA:
undetectable
3ko0B-5mpmA:
undetectable
3ko0C-5mpmA:
undetectable
3ko0D-5mpmA:
1.0
3ko0A-5mpmA:
24.47
3ko0B-5mpmA:
24.47
3ko0C-5mpmA:
24.47
3ko0D-5mpmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 GLU A 309
LEU A  65
ILE A  94
ASP A 799
SER A 766
None
CZA  A1002 (-4.1A)
None
None
None
1.38A 3ko0C-5mpmA:
undetectable
3ko0D-5mpmA:
0.9
3ko0E-5mpmA:
undetectable
3ko0F-5mpmA:
undetectable
3ko0C-5mpmA:
24.47
3ko0D-5mpmA:
24.47
3ko0E-5mpmA:
24.47
3ko0F-5mpmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 ASP A 799
SER A 766
LEU A  65
ILE A  94
GLU A 309
None
None
CZA  A1002 (-4.1A)
None
None
1.34A 3ko0C-5mpmA:
undetectable
3ko0D-5mpmA:
1.0
3ko0E-5mpmA:
undetectable
3ko0F-5mpmA:
undetectable
3ko0C-5mpmA:
24.47
3ko0D-5mpmA:
24.47
3ko0E-5mpmA:
24.47
3ko0F-5mpmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 GLU A 309
LEU A  65
ILE A  94
ASP A 799
SER A 766
None
CZA  A1002 (-4.1A)
None
None
None
1.33A 3ko0E-5mpmA:
undetectable
3ko0F-5mpmA:
undetectable
3ko0G-5mpmA:
undetectable
3ko0H-5mpmA:
undetectable
3ko0E-5mpmA:
24.47
3ko0F-5mpmA:
24.47
3ko0G-5mpmA:
24.47
3ko0H-5mpmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 12 GLU A 309
LEU A  65
ILE A  94
ASP A 799
SER A 766
None
CZA  A1002 (-4.1A)
None
None
None
1.34A 3ko0G-5mpmA:
undetectable
3ko0H-5mpmA:
undetectable
3ko0I-5mpmA:
undetectable
3ko0J-5mpmA:
undetectable
3ko0G-5mpmA:
24.47
3ko0H-5mpmA:
24.47
3ko0I-5mpmA:
24.47
3ko0J-5mpmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 ASP A 799
SER A 766
GLU A 309
LEU A  65
ILE A  94
None
None
None
CZA  A1002 (-4.1A)
None
1.38A 3ko0K-5mpmA:
undetectable
3ko0L-5mpmA:
0.9
3ko0M-5mpmA:
undetectable
3ko0N-5mpmA:
undetectable
3ko0K-5mpmA:
24.47
3ko0L-5mpmA:
24.47
3ko0M-5mpmA:
24.47
3ko0N-5mpmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 LEU A  65
ILE A  94
GLU A 309
ASP A 799
SER A 766
CZA  A1002 (-4.1A)
None
None
None
None
1.34A 3ko0O-5mpmA:
1.1
3ko0P-5mpmA:
undetectable
3ko0Q-5mpmA:
undetectable
3ko0R-5mpmA:
undetectable
3ko0O-5mpmA:
24.47
3ko0P-5mpmA:
24.47
3ko0Q-5mpmA:
24.47
3ko0R-5mpmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 10 ASP A 799
SER A 766
LEU A  65
ILE A  94
GLU A 309
None
None
CZA  A1002 (-4.1A)
None
None
1.34A 3ko0O-5mpmA:
1.0
3ko0P-5mpmA:
undetectable
3ko0Q-5mpmA:
undetectable
3ko0R-5mpmA:
undetectable
3ko0O-5mpmA:
24.47
3ko0P-5mpmA:
24.47
3ko0Q-5mpmA:
24.47
3ko0R-5mpmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 ASP A 799
SER A 766
GLU A 309
LEU A  65
ILE A  94
None
None
None
CZA  A1002 (-4.1A)
None
1.33A 3ko0Q-5mpmA:
undetectable
3ko0R-5mpmA:
undetectable
3ko0S-5mpmA:
undetectable
3ko0T-5mpmA:
undetectable
3ko0Q-5mpmA:
24.47
3ko0R-5mpmA:
24.47
3ko0S-5mpmA:
24.47
3ko0T-5mpmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
4 / 5 SER A 350
GLY A 701
THR A 357
ASP A 706
None
None
None
MGF  A1001 ( 4.0A)
1.12A 4eohA-5mpmA:
undetectable
4eohA-5mpmA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
4 / 6 GLN A 665
PHE A 657
PHE A 652
PHE A 675
None
1.21A 4fgkA-5mpmA:
2.0
4fgkA-5mpmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 12 GLY A 769
ILE A 764
SER A 765
ILE A 774
ALA A 305
None
1.13A 4qtuD-5mpmA:
2.5
4qtuD-5mpmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.45A 4qvlV-5mpmA:
undetectable
4qvlb-5mpmA:
undetectable
4qvlV-5mpmA:
17.26
4qvlb-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.45A 4qvlH-5mpmA:
undetectable
4qvlN-5mpmA:
undetectable
4qvlH-5mpmA:
17.26
4qvlN-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.46A 4qvmV-5mpmA:
undetectable
4qvmb-5mpmA:
undetectable
4qvmV-5mpmA:
17.26
4qvmb-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.46A 4qvmH-5mpmA:
undetectable
4qvmN-5mpmA:
undetectable
4qvmH-5mpmA:
17.26
4qvmN-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.47A 4qvpV-5mpmA:
undetectable
4qvpb-5mpmA:
undetectable
4qvpV-5mpmA:
17.26
4qvpb-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.47A 4qvpH-5mpmA:
undetectable
4qvpN-5mpmA:
undetectable
4qvpH-5mpmA:
17.26
4qvpN-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.46A 4qvqV-5mpmA:
undetectable
4qvqb-5mpmA:
undetectable
4qvqV-5mpmA:
17.26
4qvqb-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.47A 4qvqH-5mpmA:
undetectable
4qvqN-5mpmA:
undetectable
4qvqH-5mpmA:
17.26
4qvqN-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 10 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.48A 4qvvV-5mpmA:
undetectable
4qvvb-5mpmA:
0.0
4qvvV-5mpmA:
17.26
4qvvb-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 10 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.46A 4qvvH-5mpmA:
undetectable
4qvvN-5mpmA:
undetectable
4qvvH-5mpmA:
17.26
4qvvN-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.46A 4qvwV-5mpmA:
undetectable
4qvwb-5mpmA:
undetectable
4qvwV-5mpmA:
17.26
4qvwb-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.46A 4qvwH-5mpmA:
undetectable
4qvwN-5mpmA:
undetectable
4qvwH-5mpmA:
17.26
4qvwN-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.48A 4qvyV-5mpmA:
undetectable
4qvyb-5mpmA:
undetectable
4qvyV-5mpmA:
17.26
4qvyb-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.48A 4qvyH-5mpmA:
undetectable
4qvyN-5mpmA:
0.2
4qvyH-5mpmA:
17.26
4qvyN-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.46A 4qw1V-5mpmA:
undetectable
4qw1b-5mpmA:
undetectable
4qw1V-5mpmA:
17.26
4qw1b-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.46A 4qw1H-5mpmA:
undetectable
4qw1N-5mpmA:
undetectable
4qw1H-5mpmA:
17.26
4qw1N-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.48A 4qw3V-5mpmA:
undetectable
4qw3b-5mpmA:
undetectable
4qw3V-5mpmA:
17.26
4qw3b-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.48A 4qw3H-5mpmA:
undetectable
4qw3N-5mpmA:
undetectable
4qw3H-5mpmA:
17.26
4qw3N-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.47A 4qwuV-5mpmA:
undetectable
4qwub-5mpmA:
undetectable
4qwuV-5mpmA:
17.26
4qwub-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.46A 4qwuH-5mpmA:
undetectable
4qwuN-5mpmA:
undetectable
4qwuH-5mpmA:
17.26
4qwuN-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 12 MET A 239
ALA A 115
THR A 723
ARG A 334
LEU A 710
None
1.48A 4qzuB-5mpmA:
undetectable
4qzuB-5mpmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 12 ALA A 851
ALA A 779
GLY A 781
PHE A 782
GLU A 784
None
1.25A 4r29C-5mpmA:
2.8
4r29C-5mpmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 12 CYH A 773
LEU A 786
ALA A 850
VAL A 848
ALA A 785
None
1.22A 4x1iB-5mpmA:
undetectable
4x1iB-5mpmA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 12 VAL A 725
LEU A 180
ILE A 179
GLY A 211
LEU A  41
None
1.08A 4y8wB-5mpmA:
0.0
4y8wB-5mpmA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.45A 5bxnV-5mpmA:
undetectable
5bxnb-5mpmA:
undetectable
5bxnV-5mpmA:
17.26
5bxnb-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.45A 5bxnH-5mpmA:
undetectable
5bxnN-5mpmA:
undetectable
5bxnH-5mpmA:
17.26
5bxnN-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 9 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.47A 5cz7V-5mpmA:
undetectable
5cz7b-5mpmA:
undetectable
5cz7V-5mpmA:
17.26
5cz7b-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.47A 5cz7H-5mpmA:
undetectable
5cz7N-5mpmA:
undetectable
5cz7H-5mpmA:
17.26
5cz7N-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.46A 5d0xV-5mpmA:
undetectable
5d0xb-5mpmA:
undetectable
5d0xV-5mpmA:
17.26
5d0xb-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.47A 5d0xH-5mpmA:
undetectable
5d0xN-5mpmA:
undetectable
5d0xH-5mpmA:
17.26
5d0xN-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
4 / 6 VAL A 647
LYS A 650
ALA A 651
VAL A 632
None
0.67A 5i8fA-5mpmA:
2.1
5i8fA-5mpmA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.48A 5l5fV-5mpmA:
undetectable
5l5fb-5mpmA:
undetectable
5l5fV-5mpmA:
17.26
5l5fb-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 11 SER A 713
THR A 345
THR A 341
ALA A 698
THR A 700
None
1.48A 5l5fH-5mpmA:
undetectable
5l5fN-5mpmA:
undetectable
5l5fH-5mpmA:
17.26
5l5fN-5mpmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 12 LEU A 410
GLY A 409
ASN A 380
GLU A 381
LEU A 379
None
1.31A 5nwvA-5mpmA:
undetectable
5nwvA-5mpmA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
3 / 3 CYH A 318
MET A 756
ASN A 755
None
1.33A 5qh8A-5mpmA:
undetectable
5qh8A-5mpmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W8A_A_SAMA300_0
(AUTOINDUCER SYNTHASE)
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus
scrofa)
5 / 12 LEU A 734
VAL A 743
SER A 350
ILE A 348
THR A 345
None
1.40A 5w8aA-5mpmA:
undetectable
5w8aA-5mpmA:
undetectable