SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mqc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 5mqc VP1
(Black
queen
cell
virus) 		5 / 11 LEU A 106
VAL A 214
ILE A 172
ILE A  70
MET A 220
 None
 1.21A 1gx9A-5mqcA:
undetectable		 1gx9A-5mqcA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5mqc VP1
(Black
queen
cell
virus) 		5 / 12 LEU A  73
LEU A 106
VAL A 214
MET A 220
TYR A 116
 None
 1.20A 1kt4A-5mqcA:
undetectable		 1kt4A-5mqcA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5mqc VP1
(Black
queen
cell
virus) 		5 / 11 LEU A  73
LEU A 106
VAL A 214
MET A 220
TYR A 116
 None
 1.23A 1kt6A-5mqcA:
undetectable		 1kt6A-5mqcA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5mqc VP1
(Black
queen
cell
virus) 		5 / 11 LEU A  73
LEU A 106
VAL A 214
MET A 220
TYR A 116
 None
 1.20A 1kt7A-5mqcA:
undetectable		 1kt7A-5mqcA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 5mqc VP1
VP3
(Black
queen
cell
virus) 		4 / 4 SER C 119
ILE C 117
VAL A 109
THR C  22
 None
 1.25A 1u70A-5mqcC:
undetectable		 1u70A-5mqcC:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLX_A_CIOA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 5mqc VP1
VP3
(Black
queen
cell
virus) 		5 / 12 HIS C 113
MET C 120
LEU A  47
ASN A  43
PHE A  41
 None
 1.38A 1xlxA-5mqcC:
undetectable		 1xlxA-5mqcC:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5mqc VP2
(Black
queen
cell
virus) 		4 / 7 ILE B 211
GLN B  65
ALA B 112
ILE B  88
 None
 0.74A 2xkwA-5mqcB:
undetectable		 2xkwA-5mqcB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5mqc VP1
VP3
(Black
queen
cell
virus;
Black
queen
cell
virus) 		4 / 7 PHE C 255
LEU A 279
VAL C  98
THR C 107
 None
 0.86A 2zaxA-5mqcC:
undetectable		 2zaxA-5mqcC:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 5mqc VP3
(Black
queen
cell
virus) 		4 / 6 ASN C 228
SER C 227
ALA C 221
HIS C 140
 None
 1.18A 3aruA-5mqcC:
undetectable		 3aruA-5mqcC:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_A_VDNA1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5mqc VP1
VP2
(Black
queen
cell
virus) 		5 / 12 LEU B 138
ALA A 114
VAL B 176
PHE B 175
ILE B 173
 None
 1.06A 3b2rA-5mqcB:
undetectable		 3b2rA-5mqcB:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BMC_C_FOLC270_0
(PTERIDINE REDUCTASE)		 5mqc VP1
VP3
(Black
queen
cell
virus;
Black
queen
cell
virus) 		5 / 12 SER C 119
PRO A 230
TYR C 116
PRO A 103
GLU A  75
 None
 1.47A 3bmcC-5mqcC:
undetectable		 3bmcC-5mqcC:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 5mqc VP1
VP3
(Black
queen
cell
virus;
Black
queen
cell
virus) 		4 / 7 PHE C 255
LEU A 279
VAL C  98
THR C 107
 None
 0.86A 3fwgB-5mqcC:
undetectable		 3fwgB-5mqcC:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5mqc VP1
VP3
(Black
queen
cell
virus;
Black
queen
cell
virus) 		4 / 7 PHE C 255
LEU A 279
VAL C  98
THR C 107
 None
 0.85A 3fwiA-5mqcC:
undetectable		 3fwiA-5mqcC:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5mqc VP2
(Black
queen
cell
virus) 		5 / 12 PHE B 210
VAL B 212
ILE B 114
ILE B 163
VAL B 194
 None
 1.10A 4a97B-5mqcB:
undetectable
4a97C-5mqcB:
undetectable		 4a97B-5mqcB:
22.68
4a97C-5mqcB:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_B_NCAB1536_0
(DIPHTHERIA TOXIN)		 5mqc VP2
(Black
queen
cell
virus) 		4 / 5 HIS B 215
GLY B 214
TYR B 213
GLU B 168
 None
 1.29A 4ae1B-5mqcB:
2.6		 4ae1B-5mqcB:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5mqc VP1
VP3
(Black
queen
cell
virus;
Black
queen
cell
virus) 		4 / 4 SER C 258
ASP A 278
ASP C 101
ASP A  80
 None
 1.48A 4uciA-5mqcC:
undetectable		 4uciA-5mqcC:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5mqc VP1
VP3
(Black
queen
cell
virus;
Black
queen
cell
virus) 		4 / 4 SER C 258
ASP A 278
ASP C 101
ASP A  80
 None
 1.47A 4uciB-5mqcC:
undetectable		 4uciB-5mqcC:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 5mqc VP1
(Black
queen
cell
virus) 		5 / 12 GLY A 265
ASP A 254
PHE A  99
ALA A  82
PHE A 268
 None
 1.32A 4wh5A-5mqcA:
undetectable		 4wh5A-5mqcA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 5mqc VP3
(Black
queen
cell
virus) 		4 / 5 PHE C 242
ASP C  56
PHE C  55
VAL C 244
 None
 0.97A 5a1rA-5mqcC:
undetectable		 5a1rA-5mqcC:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 5mqc VP3
(Black
queen
cell
virus) 		4 / 6 LEU C 170
LEU C 219
PHE C 134
LEU C  80
 None
 0.79A 5gs4A-5mqcC:
undetectable		 5gs4A-5mqcC:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 5mqc VP1
(Black
queen
cell
virus) 		4 / 8 ILE A  74
ARG A  54
GLY A 215
THR A 104
 None
 1.06A 5hwaA-5mqcA:
undetectable		 5hwaA-5mqcA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 5mqc VP1
VP2
VP3
(Black
queen
cell
virus;
Black
queen
cell
virus;
Black
queen
cell
virus) 		4 / 7 LEU C 257
ILE A  74
GLU A 111
ASN B 139
 None
 0.90A 5n5dA-5mqcC:
undetectable		 5n5dA-5mqcC:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 5mqc VP2
(Black
queen
cell
virus) 		4 / 7 THR B 147
LEU B 171
VAL B 212
GLU B 166
 None
 1.10A 5tudA-5mqcB:
undetectable		 5tudA-5mqcB:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 5mqc VP1
(Black
queen
cell
virus) 		4 / 6 THR A 104
ASN A 107
ILE A  74
GLU A  75
 None
 1.01A 5uigA-5mqcA:
undetectable		 5uigA-5mqcA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5mqc VP1
VP3
(Black
queen
cell
virus;
Black
queen
cell
virus) 		5 / 12 SER C  28
VAL A 125
GLY A 166
PHE C  19
VAL A  51
 None
 1.42A 6a94A-5mqcC:
undetectable		 6a94A-5mqcC:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 5mqc VP1
VP3
(Black
queen
cell
virus;
Black
queen
cell
virus) 		4 / 6 ARG A 121
ILE C  21
ASN C  17
ASP C  26
 None
 1.43A 6dhbA-5mqcA:
undetectable		 6dhbA-5mqcA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 5mqc VP1
(Black
queen
cell
virus) 		4 / 5 THR A 237
ARG A  54
PRO A  77
ARG A  78
 None
 1.01A 6ew0B-5mqcA:
undetectable		 6ew0B-5mqcA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 5mqc VP1
(Black
queen
cell
virus) 		4 / 5 THR A 237
ARG A  54
PRO A  77
ARG A  78
 None
 1.01A 6ew0D-5mqcA:
undetectable		 6ew0D-5mqcA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 5mqc VP1
(Black
queen
cell
virus) 		4 / 5 THR A 237
ARG A  54
PRO A  77
ARG A  78
 None
 1.01A 6ew0H-5mqcA:
undetectable		 6ew0H-5mqcA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 5mqc VP1
(Black
queen
cell
virus) 		4 / 5 THR A 237
ARG A  54
PRO A  77
ARG A  78
 None
 1.01A 6ew0I-5mqcA:
undetectable		 6ew0I-5mqcA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 5mqc VP1
VP2
(Black
queen
cell
virus;
Black
queen
cell
virus) 		5 / 12 PHE B 133
GLY B 131
LEU B 130
GLY B 196
ILE A 226
 None
 1.07A 6mhtA-5mqcB:
undetectable		 6mhtA-5mqcB:
21.45