SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mqm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 12 ARG A 875
PHE A 830
PRO A 821
LEU A 706
ASP A 683
None
1.06A 1e7wA-5mqmA:
undetectable
1e7wA-5mqmA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_A_SALA3005_1
(XANTHINE
DEHYDROGENASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 9 LEU A 765
PHE A 760
THR A 688
LEU A 789
ALA A 685
None
1.36A 1fo4A-5mqmA:
undetectable
1fo4A-5mqmA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 8 ASP A 547
SER A 696
ILE A 697
GLY A 581
None
0.96A 1meiA-5mqmA:
3.7
1meiA-5mqmA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 7 ILE A 155
LEU A 158
THR A 370
LEU A 175
None
0.81A 1v54N-5mqmA:
undetectable
1v54W-5mqmA:
undetectable
1v54N-5mqmA:
19.15
1v54W-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC1383_1
(CES1 PROTEIN)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 5 TRP A  45
PRO A  44
LEU A 624
GLY A 594
None
1.36A 1ya4C-5mqmA:
undetectable
1ya4C-5mqmA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 12 LEU A 269
LEU A 252
CYH A 235
GLU A 324
LEU A 325
None
0.98A 2bxfA-5mqmA:
undetectable
2bxfA-5mqmA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 8 SER A 580
ASP A 758
SER A 759
SER A 696
None
1.03A 2cmlB-5mqmA:
undetectable
2cmlB-5mqmA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 8 SER A 580
ASP A 758
SER A 759
SER A 696
None
1.13A 2cmlD-5mqmA:
undetectable
2cmlD-5mqmA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 7 ILE A 155
LEU A 158
THR A 370
LEU A 175
None
0.81A 2dyrN-5mqmA:
undetectable
2dyrW-5mqmA:
undetectable
2dyrN-5mqmA:
19.15
2dyrW-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 8 ILE A 155
LEU A 158
THR A 370
LEU A 175
None
0.74A 2eijN-5mqmA:
0.9
2eijW-5mqmA:
undetectable
2eijN-5mqmA:
19.15
2eijW-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 8 ILE A 155
LEU A 158
THR A 370
LEU A 175
None
0.77A 2eikN-5mqmA:
undetectable
2eikW-5mqmA:
undetectable
2eikN-5mqmA:
19.15
2eikW-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 8 ILE A 155
LEU A 158
THR A 370
LEU A 175
None
0.77A 2eilN-5mqmA:
1.0
2eilW-5mqmA:
undetectable
2eilN-5mqmA:
19.15
2eilW-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 7 GLU A 865
ASN A 862
PRO A 912
ALA A 911
None
1.44A 2ejgB-5mqmA:
undetectable
2ejgB-5mqmA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 12 LEU A 839
ARG A 875
ILE A 845
ALA A 872
ASP A 838
None
1.23A 2ejtA-5mqmA:
undetectable
2ejtA-5mqmA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 12 GLY A 125
GLY A 413
ALA A 410
ALA A 127
GLU A 461
None
None
None
None
RPQ  A1204 (-3.9A)
1.05A 2gluA-5mqmA:
undetectable
2gluA-5mqmA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
3 / 3 TYR A  89
GLY A  91
PHE A  52
None
0.70A 2m2pB-5mqmA:
undetectable
2m2pB-5mqmA:
2.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
3 / 3 ARG A 670
ASN A 862
THR A1031
None
0.89A 2q63A-5mqmA:
undetectable
2q63A-5mqmA:
6.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 6 PHE A 650
TRP A 657
GLY A  73
GLY A  74
None
0.85A 2qr2A-5mqmA:
undetectable
2qr2B-5mqmA:
undetectable
2qr2A-5mqmA:
12.07
2qr2B-5mqmA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 5 TRP A 657
GLY A  73
GLY A  74
PHE A 650
None
0.84A 2qr2A-5mqmA:
undetectable
2qr2B-5mqmA:
undetectable
2qr2A-5mqmA:
12.07
2qr2B-5mqmA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 12 GLY A 600
GLY A 645
ARG A 599
ASN A 565
THR A1076
None
1.26A 2vdvE-5mqmA:
undetectable
2vdvE-5mqmA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 11 GLY A 600
GLY A 645
ARG A 599
ASN A 565
THR A1076
None
1.26A 2vdvF-5mqmA:
undetectable
2vdvF-5mqmA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
3 / 3 ARG A 714
ARG A 753
PRO A 751
None
1.03A 2wljA-5mqmA:
undetectable
2wljA-5mqmA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 7 ILE A 155
LEU A 158
THR A 370
LEU A 175
None
0.85A 3ablA-5mqmA:
undetectable
3ablJ-5mqmA:
undetectable
3ablA-5mqmA:
19.15
3ablJ-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 8 ILE A 155
LEU A 158
THR A 370
LEU A 175
None
0.74A 3ablN-5mqmA:
undetectable
3ablW-5mqmA:
undetectable
3ablN-5mqmA:
19.15
3ablW-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 8 ILE A 155
LEU A 158
THR A 370
LEU A 175
None
0.77A 3asnN-5mqmA:
undetectable
3asnW-5mqmA:
undetectable
3asnN-5mqmA:
19.15
3asnW-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 6 ASP A 653
LEU A 635
ASP A  63
LEU A  64
None
1.07A 3bj8C-5mqmA:
undetectable
3bj8D-5mqmA:
undetectable
3bj8C-5mqmA:
10.33
3bj8D-5mqmA:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 12 THR A 411
HIS A 121
ILE A 646
HIS A 456
LEU A 128
PG4  A1205 (-4.4A)
None
RPQ  A1204 ( 4.3A)
None
None
1.29A 3gwxB-5mqmA:
undetectable
3gwxB-5mqmA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 7 VAL A 686
TYR A 757
GLU A 700
PRO A 699
None
1.12A 3hs4A-5mqmA:
undetectable
3hs4A-5mqmA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
3 / 3 ARG A 637
ASP A 653
ASP A 636
None
0.85A 3jayA-5mqmA:
undetectable
3jayA-5mqmA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
3 / 3 ARG A 637
ASP A 653
ASP A 636
None
0.72A 3jb2A-5mqmA:
undetectable
3jb2A-5mqmA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
3 / 3 ARG A 637
ASP A 653
ASP A 636
None
0.71A 3jb3A-5mqmA:
undetectable
3jb3A-5mqmA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_B_VIAB901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 11 ASN A 573
LEU A 549
ALA A 682
LEU A 706
THR A 688
None
1.44A 3jwqB-5mqmA:
undetectable
3jwqC-5mqmA:
undetectable
3jwqB-5mqmA:
15.66
3jwqC-5mqmA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
3 / 3 ARG A 695
GLU A 700
TYR A 757
None
0.84A 3k37B-5mqmA:
undetectable
3k37B-5mqmA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 8 GLY A 660
CYH A 671
PHE A 562
PHE A 626
PHE A 595
None
1.44A 3ko0D-5mqmA:
undetectable
3ko0E-5mqmA:
undetectable
3ko0D-5mqmA:
6.60
3ko0E-5mqmA:
6.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_B_TPFB490_1
(STEROL 14-ALPHA
DEMETHYLASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 9 PHE A 650
TYR A 629
ALA A 661
ALA A  70
LEU A 116
None
1.28A 3l4dB-5mqmA:
undetectable
3l4dB-5mqmA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_A_SAMA465_0
(RRNA METHYLASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 12 ALA A 582
GLY A 780
GLY A 781
VAL A 555
ASP A 556
None
0.99A 3m6vA-5mqmA:
undetectable
3m6vA-5mqmA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_B_SAMB465_0
(RRNA METHYLASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 12 ALA A 582
GLY A 780
GLY A 781
VAL A 555
ASP A 556
None
0.99A 3m6vB-5mqmA:
undetectable
3m6vB-5mqmA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6W_A_SAMA465_0
(RRNA METHYLASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 12 ALA A 582
GLY A 780
GLY A 781
VAL A 555
ASP A 556
None
1.01A 3m6wA-5mqmA:
undetectable
3m6wA-5mqmA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 12 TYR A 170
LEU A 158
SER A 146
VAL A 150
LEU A 390
None
1.30A 3m7rA-5mqmA:
undetectable
3m7rA-5mqmA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 8 GLN A 851
HIS A 849
VAL A 681
ARG A 879
None
1.04A 3uy4A-5mqmA:
2.8
3uy4A-5mqmA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
3 / 3 GLY A 607
THR A1031
ASN A 913
None
0.73A 3v4tD-5mqmA:
1.2
3v4tD-5mqmA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 10 TYR A 954
LEU A 949
LEU A1096
VAL A1021
VAL A1019
None
1.30A 4c9pB-5mqmA:
undetectable
4c9pB-5mqmA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 8 ASN A 658
ASN A1055
THR A1056
TRP A 656
None
1.26A 4d1yA-5mqmA:
4.2
4d1yB-5mqmA:
3.9
4d1yA-5mqmA:
12.24
4d1yB-5mqmA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 12 ASP A 614
TYR A 617
ASN A 616
ALA A 592
TYR A 667
None
1.29A 4dajA-5mqmA:
undetectable
4dajA-5mqmA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
3 / 3 GLU A 239
ARG A 326
HIS A 328
None
0.82A 4kf9A-5mqmA:
undetectable
4kf9A-5mqmA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 7 TYR A 227
ASN A 282
GLU A 324
GLU A 239
None
1.20A 4mi4A-5mqmA:
0.7
4mi4C-5mqmA:
undetectable
4mi4A-5mqmA:
10.42
4mi4C-5mqmA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA303_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 4 LEU A 342
VAL A 343
GLU A 337
ARG A 345
None
1.37A 4ww7A-5mqmA:
undetectable
4ww7A-5mqmA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
3 / 3 ASP A 758
ARG A 875
ARG A 775
None
0.76A 4x5iA-5mqmA:
undetectable
4x5iA-5mqmA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 7 ILE A 155
LEU A 158
THR A 370
LEU A 175
None
0.79A 5b1bA-5mqmA:
undetectable
5b1bJ-5mqmA:
undetectable
5b1bA-5mqmA:
19.15
5b1bJ-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 12 GLY A 463
LEU A 342
LEU A 128
THR A 543
GLY A 338
None
1.14A 5d4uA-5mqmA:
undetectable
5d4uA-5mqmA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 12 GLY A 463
LEU A 342
LEU A 128
THR A 543
GLY A 338
None
1.11A 5d4uB-5mqmA:
undetectable
5d4uB-5mqmA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 9 ALA A 388
LEU A 158
GLY A 157
LEU A 386
LEU A 369
None
1.22A 5dqfA-5mqmA:
undetectable
5dqfA-5mqmA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 4 VAL A 887
ALA A 663
ILE A1029
THR A1028
None
1.18A 5e4dB-5mqmA:
undetectable
5e4dB-5mqmA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 7 ILE A 155
LEU A 158
THR A 370
LEU A 175
None
0.80A 5iy5A-5mqmA:
undetectable
5iy5J-5mqmA:
undetectable
5iy5A-5mqmA:
19.15
5iy5J-5mqmA:
4.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
5 / 12 ALA A1017
PHE A 562
ILE A 621
TYR A 617
PHE A 595
None
1.11A 5jlcA-5mqmA:
undetectable
5jlcA-5mqmA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
3 / 3 ARG A 730
PRO A 567
ASN A 565
None
1.04A 5jwaA-5mqmA:
undetectable
5jwaH-5mqmA:
undetectable
5jwaA-5mqmA:
18.17
5jwaH-5mqmA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
3 / 3 CYH A 194
MET A 211
ASN A 210
None
1.27A 5qh8A-5mqmA:
undetectable
5qh8A-5mqmA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
3 / 3 HIS A 569
SER A 566
ARG A 599
None
0.92A 5u63A-5mqmA:
undetectable
5u63A-5mqmA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 7 PHE A 649
PRO A 639
ILE A1074
THR A 642
None
1.06A 5vkqA-5mqmA:
undetectable
5vkqD-5mqmA:
undetectable
5vkqA-5mqmA:
19.71
5vkqD-5mqmA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 5 ARG A 775
MET A 776
THR A 777
LEU A 778
None
1.24A 5x19J-5mqmA:
undetectable
5x19J-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 5 ARG A 775
MET A 776
THR A 777
LEU A 778
None
1.19A 5x1bJ-5mqmA:
undetectable
5x1bJ-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 8 ILE A 155
LEU A 158
THR A 370
LEU A 175
None
0.78A 5xdxN-5mqmA:
undetectable
5xdxW-5mqmA:
undetectable
5xdxN-5mqmA:
19.15
5xdxW-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 5 ILE A 981
PHE A 971
TYR A 990
THR A1054
None
1.21A 5z84N-5mqmA:
undetectable
5z84W-5mqmA:
undetectable
5z84N-5mqmA:
19.15
5z84W-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 8 ILE A 155
LEU A 158
THR A 370
LEU A 175
None
0.82A 5zcoA-5mqmA:
undetectable
5zcoJ-5mqmA:
undetectable
5zcoA-5mqmA:
19.15
5zcoJ-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 8 ILE A 155
LEU A 158
THR A 370
LEU A 175
None
0.78A 5zcqN-5mqmA:
undetectable
5zcqW-5mqmA:
undetectable
5zcqN-5mqmA:
19.15
5zcqW-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 6 ILE A 217
MET A 211
ASN A 210
ASP A 212
None
1.15A 6dhbA-5mqmA:
undetectable
6dhbA-5mqmA:
6.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 5 ARG A 775
MET A 776
THR A 777
LEU A 778
None
1.38A 6nknW-5mqmA:
undetectable
6nknW-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 7 ILE A 155
LEU A 158
THR A 370
LEU A 175
None
0.79A 6nmfA-5mqmA:
0.7
6nmfJ-5mqmA:
undetectable
6nmfA-5mqmA:
19.15
6nmfJ-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 7 ILE A 155
LEU A 158
THR A 370
LEU A 175
None
0.72A 6nmpA-5mqmA:
0.8
6nmpJ-5mqmA:
undetectable
6nmpA-5mqmA:
19.15
6nmpJ-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron)
4 / 5 ILE A 155
LEU A 158
THR A 370
LEU A 175
None
0.74A 6nmpN-5mqmA:
undetectable
6nmpW-5mqmA:
undetectable
6nmpN-5mqmA:
19.15
6nmpW-5mqmA:
4.20