SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mqo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ILE A 330
TYR A 304
PHE A 391
PHE A 287
 None
 1.00A 1e71M-5mqoA:
undetectable		 1e71M-5mqoA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ILE A 330
TYR A 304
PHE A 391
PHE A 287
 None
 0.99A 1e72M-5mqoA:
undetectable		 1e72M-5mqoA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ILE A 330
TYR A 304
PHE A 391
PHE A 287
 None
 1.02A 1e73M-5mqoA:
undetectable		 1e73M-5mqoA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 433
ALA A 384
ALA A 340
VAL A 692
HIS A 379
 None
 1.33A 1kt4A-5mqoA:
undetectable		 1kt4A-5mqoA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		4 / 4 VAL A 563
ALA A 561
LEU A 575
PHE A 533
 None
 1.04A 1q97B-5mqoA:
undetectable		 1q97B-5mqoA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 LEU A 575
ALA A 542
LEU A 544
SER A 552
 None
 0.99A 1tz8C-5mqoA:
undetectable
1tz8D-5mqoA:
undetectable		 1tz8C-5mqoA:
9.61
1tz8D-5mqoA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 346
GLU A 381
TYR A 336
 None
 0.82A 1wsvA-5mqoA:
undetectable		 1wsvA-5mqoA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 469
GLN A 470
LEU A  25
LEU A 390
THR A 382
 None
 1.46A 2oaxC-5mqoA:
undetectable		 2oaxC-5mqoA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 PRO A 440
LEU A 439
ARG A 434
 None
 0.76A 3aqiB-5mqoA:
undetectable		 3aqiB-5mqoA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 301
GLY A 306
TYR A 304
ILE A 268
SER A 264
 None
 1.49A 3bwmA-5mqoA:
undetectable		 3bwmA-5mqoA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O0Q_A_ADNA1004_1
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		5 / 9 ASN A 385
SER A 418
GLY A 419
CYH A 411
THR A 465
 None
 1.44A 3o0qA-5mqoA:
0.8		 3o0qA-5mqoA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 601
LEU A 645
THR A 635
 None
 0.54A 3oxcA-5mqoA:
undetectable		 3oxcA-5mqoA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		5 / 9 THR A 475
THR A  39
ASN A  38
GLY A  24
ASP A  27
 None
 1.47A 3sfuA-5mqoA:
undetectable		 3sfuA-5mqoA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 THR A 475
THR A  39
ASN A  38
GLY A  24
ASP A  27
 None
 1.43A 3sfuC-5mqoA:
undetectable		 3sfuC-5mqoA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ASN A 385
ALA A 340
TYR A 367
ALA A 297
 None
 1.23A 3twpD-5mqoA:
2.9		 3twpD-5mqoA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLN A 505
THR A  47
ASN A 489
 None
 0.88A 3v4tE-5mqoA:
undetectable		 3v4tE-5mqoA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 SER A 641
ILE A 642
TRP A 511
PHE A  50
 None
 1.22A 4cx7A-5mqoA:
undetectable
4cx7B-5mqoA:
undetectable		 4cx7A-5mqoA:
20.96
4cx7B-5mqoA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 SER A 641
ILE A 642
TRP A 511
PHE A  50
 None
 1.23A 4cx7C-5mqoA:
undetectable
4cx7D-5mqoA:
undetectable		 4cx7C-5mqoA:
20.96
4cx7D-5mqoA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EVR_A_BEZA401_0
(PUTATIVE ABC
TRANSPORTER SUBUNIT,
SUBSTRATE-BINDING
COMPONENT)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 407
VAL A 331
TYR A 367
ALA A 293
PHE A 391
 None
 1.41A 4evrA-5mqoA:
undetectable		 4evrA-5mqoA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ILE A 642
GLY A  52
GLU A  53
GLN A 505
 None
 0.96A 4g0uB-5mqoA:
undetectable		 4g0uB-5mqoA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_1
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 SER A  31
GLU A 397
ASP A  27
ASN A 471
 None
 1.48A 4pclA-5mqoA:
1.2		 4pclA-5mqoA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 HIS A 244
CYH A 241
GLY A 247
HIS A 196
 None
 1.32A 5a5zC-5mqoA:
undetectable		 5a5zC-5mqoA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 GLU A 316
THR A 314
HIS A 244
LEU A 267
 None
 1.27A 5axaA-5mqoA:
undetectable		 5axaA-5mqoA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 GLN A 468
ASN A 461
VAL A 408
TYR A 472
LEU A 485
 None
 1.28A 5jh7D-5mqoA:
undetectable		 5jh7D-5mqoA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSA_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 301
GLY A 306
TYR A 304
ILE A 268
SER A 264
 None
 1.48A 5lsaA-5mqoA:
undetectable		 5lsaA-5mqoA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 HIS A 296
ASP A 280
HIS A 364
 None
 0.78A 5n1tW-5mqoA:
undetectable		 5n1tW-5mqoA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A  48
VAL A 116
HIS A  45
 None
 0.81A 6a5yD-5mqoA:
undetectable		 6a5yD-5mqoA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA717_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 292
ASP A 329
ARG A 333
LYS A 334
 None
 1.24A 6dwdA-5mqoA:
undetectable		 6dwdA-5mqoA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ASP A 222
VAL A 133
ARG A 464
GLN A 468
 None
 1.21A 6fbvD-5mqoA:
undetectable		 6fbvD-5mqoA:
19.23