SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mqp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 11 ASP A 397
ARG A 368
GLY A 338
CYH A 465
GLY A 419
 None
 1.33A 1jr1A-5mqpA:
undetectable		 1jr1A-5mqpA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A  97
ILE A  22
TRP A  23
 None
 1.08A 1m8eB-5mqpA:
undetectable		 1m8eB-5mqpA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		4 / 5 GLU A 431
ARG A 346
LEU A 360
ASP A 361
 None
 1.29A 1n13B-5mqpA:
undetectable
1n13C-5mqpA:
undetectable		 1n13B-5mqpA:
9.76
1n13C-5mqpA:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A  97
ILE A  22
TRP A  23
 None
 1.14A 1nodB-5mqpA:
undetectable		 1nodB-5mqpA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 10 PHE A 383
PHE A 455
LEU A 420
VAL A 422
VAL A 407
 None
 1.36A 1q23E-5mqpA:
undetectable		 1q23E-5mqpA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 11 THR A 322
PHE A 319
VAL A 375
PHE A 383
THR A 394
 None
 1.38A 1q23F-5mqpA:
undetectable		 1q23F-5mqpA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 11 PHE A 383
PHE A 455
LEU A 420
VAL A 422
VAL A 407
 None
 1.31A 1q23I-5mqpA:
undetectable		 1q23I-5mqpA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 10 PHE A 383
PHE A 455
LEU A 420
VAL A 422
VAL A 407
 None
 1.38A 1q23K-5mqpA:
undetectable		 1q23K-5mqpA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_2
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		4 / 7 VAL A 407
VAL A 402
TYR A 472
CYH A 453
 None
 1.14A 1t46A-5mqpA:
undetectable		 1t46A-5mqpA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 11 VAL A 509
VAL A 527
ASN A 512
GLU A 479
ILE A 468
 None
 1.30A 1t6zA-5mqpA:
undetectable		 1t6zA-5mqpA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 11 VAL A 509
VAL A 527
ASN A 512
GLU A 479
ILE A 468
 None
 1.31A 1t6zB-5mqpA:
undetectable		 1t6zB-5mqpA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		4 / 5 VAL A 458
GLY A 459
VAL A 486
TRP A 463
 None
 1.36A 1tkqB-5mqpA:
undetectable		 1tkqB-5mqpA:
2.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A  83
ARG A  51
ILE A 312
 None
 0.77A 1uobA-5mqpA:
undetectable		 1uobA-5mqpA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		4 / 5 PRO A 487
GLY A 419
ASN A 418
GLY A 417
 None
 1.01A 1zlqA-5mqpA:
undetectable		 1zlqA-5mqpA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 483
ILE A 491
ASN A 541
VAL A 509
ILE A 546
 None
 0.90A 2nnhA-5mqpA:
undetectable		 2nnhA-5mqpA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A  97
ILE A  22
TRP A  23
 None
 1.11A 2nodB-5mqpA:
undetectable		 2nodB-5mqpA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A  43
VAL A 301
ASP A  86
THR A  94
ILE A  96
 None
 1.24A 3bf1A-5mqpA:
undetectable
3bf1B-5mqpA:
undetectable		 3bf1A-5mqpA:
17.39
3bf1B-5mqpA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A 105
SER A 107
THR A 318
ILE A 299
ILE A 295
 None
 1.15A 3ddyA-5mqpA:
undetectable		 3ddyA-5mqpA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A  97
ILE A  22
TRP A  23
 None
 0.99A 3e68A-5mqpA:
undetectable		 3e68A-5mqpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A  97
ILE A  22
TRP A  23
 None
 1.06A 3e6tB-5mqpA:
undetectable		 3e6tB-5mqpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		4 / 7 ILE A  24
PHE A 314
PHE A 319
GLY A  71
 None
 1.02A 3em0B-5mqpA:
undetectable		 3em0B-5mqpA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_A_TOPA200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 10 ALA A 177
LEU A 251
VAL A 173
ALA A 193
ILE A 208
 None
 0.95A 3fl9A-5mqpA:
undetectable		 3fl9A-5mqpA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 10 ALA A 177
LEU A 251
VAL A 173
ALA A 193
ILE A 208
 None
 1.00A 3fl9F-5mqpA:
undetectable		 3fl9F-5mqpA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		4 / 8 VAL A 402
VAL A 301
ILE A 450
VAL A 407
 None
 0.90A 3hjoB-5mqpA:
undetectable		 3hjoB-5mqpA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		4 / 5 VAL A 182
LEU A 181
ILE A 220
ALA A 218
 None
 0.99A 3n8yB-5mqpA:
undetectable		 3n8yB-5mqpA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_1
(FIV PROTEASE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 10 LEU A  43
ALA A  50
GLY A  88
VAL A  80
LEU A  47
 None
 0.92A 3ogpA-5mqpA:
undetectable		 3ogpA-5mqpA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		4 / 6 PHE A 383
PHE A 319
ALA A 372
THR A 297
 None
 1.12A 3t3sB-5mqpA:
undetectable		 3t3sB-5mqpA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 12 PHE A 425
ASP A 397
ILE A 483
THR A 394
ALA A 525
 None
 1.36A 3ua1A-5mqpA:
undetectable		 3ua1A-5mqpA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWQ_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 337
TYR A 472
TRP A 497
SER A 492
GLY A 338
 None
 0.99A 3vwqA-5mqpA:
undetectable		 3vwqA-5mqpA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 9 VAL A 524
ALA A 525
TYR A 528
GLY A 464
GLY A 490
 None
 1.34A 4mm5A-5mqpA:
undetectable		 4mm5A-5mqpA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 9 VAL A 524
TYR A 528
GLY A 464
SER A 492
GLY A 490
 None
 1.33A 4mm5A-5mqpA:
undetectable		 4mm5A-5mqpA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA603_1
(TRANSPORTER)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 10 VAL A 524
TYR A 528
GLY A 464
SER A 492
GLY A 490
 None
 1.31A 4mmcA-5mqpA:
undetectable		 4mmcA-5mqpA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 9 VAL A 524
ALA A 525
TYR A 528
GLY A 464
GLY A 490
 None
 1.38A 4mmeA-5mqpA:
undetectable		 4mmeA-5mqpA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 9 VAL A 524
ALA A 525
TYR A 528
GLY A 464
GLY A 490
 None
 1.34A 4mmfA-5mqpA:
undetectable		 4mmfA-5mqpA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 9 VAL A 524
ALA A 525
TYR A 528
GLY A 464
GLY A 490
 None
 1.32A 4mmfB-5mqpA:
undetectable		 4mmfB-5mqpA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKN_B_KANB403_1
(L-LACTATE
DEHYDROGENASE A
CHAIN)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 9 ASP A  30
ALA A  46
ARG A  60
ILE A  22
ILE A  24
 None
 1.46A 4oknB-5mqpA:
undetectable		 4oknB-5mqpA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 9 VAL A 458
ILE A 546
VAL A 524
ALA A 525
ALA A 467
 None
 1.24A 4oqrA-5mqpA:
undetectable		 4oqrA-5mqpA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_A_NOVA2000_1
(DNA GYRASE SUBUNIT B)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 12 SER A 310
GLN A  49
ILE A  65
SER A  92
ARG A  51
 None
 1.31A 4uroA-5mqpA:
undetectable		 4uroA-5mqpA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 12 SER A 310
GLN A  49
ILE A  65
SER A  92
ARG A  51
 None
 1.17A 4uroB-5mqpA:
undetectable		 4uroB-5mqpA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A  47
ARG A  48
ARG A  83
 None
 0.89A 4yiaB-5mqpA:
undetectable		 4yiaB-5mqpA:
4.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 565
TRP A 495
ASN A 362
 None
 1.13A 5dv4A-5mqpA:
undetectable		 5dv4A-5mqpA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E2I_A_DMEA605_1
(ACETYLCHOLINESTERASE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		4 / 6 ASP A 523
TYR A 488
PHE A 559
TYR A 562
 None
 1.49A 5e2iA-5mqpA:
undetectable		 5e2iA-5mqpA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E2I_A_DMEA605_1
(ACETYLCHOLINESTERASE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		4 / 6 TYR A 488
ASP A 523
PHE A 559
TYR A 562
 None
 1.00A 5e2iA-5mqpA:
undetectable		 5e2iA-5mqpA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 12 TYR A 528
GLY A 496
THR A 432
LEU A 335
HIS A 233
 None
 1.30A 5esgA-5mqpA:
undetectable		 5esgA-5mqpA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_1
(CATECHOL
O-METHYLTRANSFERASE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		4 / 5 SER A 163
SER A 227
GLN A 224
ASP A 165
 None
 1.47A 5fhrB-5mqpA:
undetectable		 5fhrB-5mqpA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		4 / 8 HIS A 233
GLN A 230
LEU A 335
LEU A 341
 None
 1.11A 5hs6A-5mqpA:
undetectable		 5hs6A-5mqpA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 9 ARG A 368
LEU A 391
ILE A 415
GLY A 417
LEU A 396
 None
 0.82A 5o96A-5mqpA:
undetectable
5o96B-5mqpA:
undetectable		 5o96A-5mqpA:
17.29
5o96B-5mqpA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		3 / 3 HIS A 433
GLU A 565
TRP A 497
 None
 1.12A 5odqD-5mqpA:
undetectable		 5odqD-5mqpA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		3 / 3 HIS A 433
GLU A 565
TRP A 497
 None
 1.16A 5odrD-5mqpA:
undetectable		 5odrD-5mqpA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 312
GLY A 303
ALA A 377
ALA A 401
PHE A 305
 None
 1.05A 5zw4A-5mqpA:
undetectable		 5zw4A-5mqpA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 12 PHE A 455
LEU A 420
ARG A 413
ILE A 415
ASP A 389
 None
 1.25A 6bxmA-5mqpA:
undetectable		 6bxmA-5mqpA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_A_NCTA402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 497
CYH A 202
TRP A 495
LEU A 335
 None
 1.48A 6cnjA-5mqpA:
undetectable
6cnjB-5mqpA:
undetectable		 6cnjA-5mqpA:
12.66
6cnjB-5mqpA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNK_B_NCTB402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 497
CYH A 202
TRP A 495
LEU A 335
 None
 1.45A 6cnkB-5mqpA:
undetectable
6cnkC-5mqpA:
undetectable		 6cnkB-5mqpA:
12.66
6cnkC-5mqpA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		3 / 3 LYS A 272
VAL A 123
ASP A 125
 None
 0.62A 6fgdA-5mqpA:
undetectable		 6fgdA-5mqpA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A 104
ILE A 317
VAL A  95
ILE A  96
CYH A  68
 None
 1.19A 6gsdA-5mqpA:
undetectable		 6gsdA-5mqpA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5mqp GLYCOSIDE HYDROLASE
BT_1002
(Bacteroides
thetaiotaomicron) 		4 / 7 HIS A 510
GLU A 540
ASP A 574
GLU A 594
 None
 1.16A 6mn4F-5mqpA:
undetectable		 6mn4F-5mqpA:
18.31