SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mqx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 5mqx NON-STRUCTURAL
PROTEIN3
(Venezuelan
equine
encephalitis
virus) 		4 / 8 SER A  91
ILE A  92
GLU A  90
LEU A 132
 None
 0.66A 1eupA-5mqxA:
undetectable		 1eupA-5mqxA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA205_0
(OXIDOREDUCTASE)		 5mqx NON-STRUCTURAL
PROTEIN3
(Venezuelan
equine
encephalitis
virus) 		4 / 5 SER A 115
GLY A 116
ARG A 120
GLU A  78
 None
 1.18A 4r82A-5mqxA:
undetectable
4r82B-5mqxA:
undetectable		 4r82A-5mqxA:
undetectable
4r82B-5mqxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_H_SAMH501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5mqx NON-STRUCTURAL
PROTEIN3
(Venezuelan
equine
encephalitis
virus) 		5 / 10 LEU A 109
PRO A  71
GLY A  81
VAL A  52
ALA A  88
 None
 0.97A 5o96G-5mqxA:
2.3
5o96H-5mqxA:
2.7		 5o96G-5mqxA:
undetectable
5o96H-5mqxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5mqx NON-STRUCTURAL
PROTEIN3
(Venezuelan
equine
encephalitis
virus) 		5 / 10 ALA A  86
LEU A  85
GLY A  81
ILE A  11
LEU A  37
 None
None
None
APR  A 201 (-3.3A)
None
 1.25A 5oy01-5mqxA:
undetectable
5oy07-5mqxA:
undetectable		 5oy01-5mqxA:
18.09
5oy07-5mqxA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 5mqx NON-STRUCTURAL
PROTEIN3
(Venezuelan
equine
encephalitis
virus) 		5 / 12 ILE A 106
LEU A 128
GLY A  53
ALA A  88
LEU A  85
 None
 1.19A 5zwrA-5mqxA:
undetectable		 5zwrA-5mqxA:
undetectable