SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mqz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 228
THR A 199
PRO A 201
TAM  A 303 (-3.9A)
None
None
0.84A 1a7yA-5mqzA:
undetectable
1a7yA-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 228
THR A 199
PRO A 201
TAM  A 303 (-3.9A)
None
None
0.86A 1a7yB-5mqzA:
undetectable
1a7yB-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 6 LEU A  26
ILE A  91
ARG A  89
VAL A  18
None
1.09A 1db1A-5mqzA:
undetectable
1db1A-5mqzA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 199
PRO A 201
THR A 228
None
None
TAM  A 303 (-3.9A)
0.88A 1i3wE-5mqzA:
undetectable
1i3wE-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 228
THR A 199
PRO A 201
TAM  A 303 (-3.9A)
None
None
0.81A 1i3wE-5mqzA:
undetectable
1i3wE-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 228
THR A 199
PRO A 201
TAM  A 303 (-3.9A)
None
None
0.86A 1i3wF-5mqzA:
undetectable
1i3wF-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 199
PRO A 201
THR A 228
None
None
TAM  A 303 (-3.9A)
0.86A 1i3wG-5mqzA:
undetectable
1i3wG-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 228
THR A 199
PRO A 201
TAM  A 303 (-3.9A)
None
None
0.83A 1i3wH-5mqzA:
undetectable
1i3wH-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
5 / 9 GLY A  97
PHE A  21
LEU A  26
SER A  19
GLY A  24
None
1.18A 1jhoA-5mqzA:
undetectable
1jhoA-5mqzA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
5 / 9 GLY A  97
PHE A  21
LEU A  26
SER A  19
GLY A  24
None
1.20A 1jhrA-5mqzA:
undetectable
1jhrA-5mqzA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
5 / 9 GLY A  97
PHE A  21
LEU A  26
SER A  19
GLY A  24
None
1.20A 1jhyA-5mqzA:
undetectable
1jhyA-5mqzA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
5 / 9 GLY A  97
PHE A  21
LEU A  26
SER A  19
GLY A  24
None
1.21A 1l4nA-5mqzA:
undetectable
1l4nA-5mqzA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
5 / 9 GLY A  97
PHE A  21
LEU A  26
SER A  19
GLY A  24
None
1.18A 1l5kA-5mqzA:
undetectable
1l5kA-5mqzA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
5 / 9 GLY A  97
PHE A  21
LEU A  26
SER A  19
GLY A  24
None
1.20A 1l5lA-5mqzA:
undetectable
1l5lA-5mqzA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
5 / 9 GLY A  97
PHE A  21
LEU A  26
SER A  19
GLY A  24
None
1.20A 1l5mA-5mqzA:
undetectable
1l5mA-5mqzA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 199
PRO A 201
THR A 228
None
None
TAM  A 303 (-3.9A)
0.83A 1mnvD-5mqzA:
undetectable
1mnvD-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 199
PRO A 201
THR A 228
None
None
TAM  A 303 (-3.9A)
0.84A 1ovfB-5mqzA:
undetectable
1ovfB-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 228
THR A 199
PRO A 201
TAM  A 303 (-3.9A)
None
None
0.84A 1qfiA-5mqzA:
undetectable
1qfiA-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 228
THR A 199
PRO A 201
TAM  A 303 (-3.9A)
None
None
0.84A 1qfiB-5mqzA:
undetectable
1qfiB-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 199
PRO A 201
THR A 228
None
None
TAM  A 303 (-3.9A)
0.83A 1unjF-5mqzA:
undetectable
1unjF-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 228
THR A 199
PRO A 201
TAM  A 303 (-3.9A)
None
None
0.84A 1unjF-5mqzA:
undetectable
1unjF-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 199
PRO A 201
THR A 228
None
None
TAM  A 303 (-3.9A)
0.79A 1unjL-5mqzA:
undetectable
1unjL-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 228
THR A 199
PRO A 201
TAM  A 303 (-3.9A)
None
None
0.81A 1unjL-5mqzA:
undetectable
1unjL-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 199
PRO A 201
THR A 228
None
None
TAM  A 303 (-3.9A)
0.82A 1unjR-5mqzA:
undetectable
1unjR-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 228
THR A 199
PRO A 201
TAM  A 303 (-3.9A)
None
None
0.83A 1unjR-5mqzA:
undetectable
1unjR-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 228
THR A 199
PRO A 201
TAM  A 303 (-3.9A)
None
None
0.79A 1unjW-5mqzA:
undetectable
1unjW-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 199
PRO A 201
THR A 228
None
None
TAM  A 303 (-3.9A)
0.80A 1unjX-5mqzA:
undetectable
1unjX-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 228
THR A 199
PRO A 201
TAM  A 303 (-3.9A)
None
None
0.79A 1unjX-5mqzA:
undetectable
1unjX-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 199
PRO A 201
THR A 228
None
None
TAM  A 303 (-3.9A)
0.77A 1unmE-5mqzA:
undetectable
1unmE-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 228
THR A 199
PRO A 201
TAM  A 303 (-3.9A)
None
None
0.81A 1unmE-5mqzA:
undetectable
1unmE-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
5 / 8 TYR A  87
ARG A  89
GLY A 245
THR A 246
ALA A 247
None
None
LLP  A 150 ( 3.4A)
LLP  A 150 ( 3.7A)
None
0.44A 2a1hA-5mqzA:
28.4
2a1hB-5mqzA:
28.4
2a1hA-5mqzA:
13.00
2a1hB-5mqzA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
5 / 10 TYR A  87
ARG A  89
GLY A 245
THR A 246
ALA A 247
None
None
LLP  A 150 ( 3.4A)
LLP  A 150 ( 3.7A)
None
0.32A 2coiA-5mqzA:
28.7
2coiB-5mqzA:
29.0
2coiA-5mqzA:
10.78
2coiB-5mqzA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
5 / 10 TYR A  87
ARG A  89
GLY A 245
THR A 246
ALA A 247
None
None
LLP  A 150 ( 3.4A)
LLP  A 150 ( 3.7A)
None
0.26A 2coiA-5mqzA:
28.8
2coiB-5mqzA:
29.0
2coiA-5mqzA:
10.78
2coiB-5mqzA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
6 / 11 PHE A  32
TYR A  87
ARG A  89
GLY A 245
THR A 246
ALA A 247
LLP  A 150 ( 3.9A)
None
None
LLP  A 150 ( 3.4A)
LLP  A 150 ( 3.7A)
None
0.47A 2cojA-5mqzA:
28.4
2cojB-5mqzA:
28.6
2cojA-5mqzA:
10.78
2cojB-5mqzA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
5 / 9 TYR A  87
ARG A  89
GLY A 245
THR A 246
ALA A 247
None
None
LLP  A 150 ( 3.4A)
LLP  A 150 ( 3.7A)
None
0.35A 2cojA-5mqzA:
28.4
2cojB-5mqzA:
28.6
2cojA-5mqzA:
10.78
2cojB-5mqzA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
5 / 10 THR A 134
LEU A 175
GLY A 231
VAL A 241
VAL A 191
None
1.34A 2cp4A-5mqzA:
undetectable
2cp4A-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_A_GBNA2414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
7 / 8 TYR A  87
ARG A  89
GLY A 186
GLY A 245
THR A 246
ALA A 247
ALA A 248
None
None
LLP  A 150 ( 3.9A)
LLP  A 150 ( 3.4A)
LLP  A 150 ( 3.7A)
None
None
0.28A 2ej3A-5mqzA:
39.3
2ej3A-5mqzA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_B_GBNB914_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
9 / 10 PHE A  32
TYR A  87
ARG A  89
TYR A 154
GLY A 186
GLY A 245
THR A 246
ALA A 247
ALA A 248
LLP  A 150 ( 3.9A)
None
None
LLP  A 150 ( 4.3A)
LLP  A 150 ( 3.9A)
LLP  A 150 ( 3.4A)
LLP  A 150 ( 3.7A)
None
None
0.36A 2ej3B-5mqzA:
39.2
2ej3B-5mqzA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 6 THR A 134
LEU A 232
VAL A 241
VAL A 191
None
0.94A 2z97A-5mqzA:
undetectable
2z97A-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 7 PHE A  43
GLU A 282
SER A 278
ARG A  44
None
1.33A 3dqtA-5mqzA:
undetectable
3dqtB-5mqzA:
undetectable
3dqtA-5mqzA:
13.60
3dqtB-5mqzA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 8 PHE A  43
GLU A 282
SER A 278
ARG A  44
None
1.36A 3jx1A-5mqzA:
undetectable
3jx1B-5mqzA:
undetectable
3jx1A-5mqzA:
15.18
3jx1B-5mqzA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 7 SER A 278
ARG A  44
PHE A  43
GLU A 282
None
1.46A 3n5tA-5mqzA:
undetectable
3n5tB-5mqzA:
undetectable
3n5tA-5mqzA:
12.81
3n5tB-5mqzA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 8 PHE A  43
GLU A 282
SER A 278
ARG A  44
None
1.34A 3nlyA-5mqzA:
undetectable
3nlyB-5mqzA:
undetectable
3nlyA-5mqzA:
15.18
3nlyB-5mqzA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 5 ASN A  82
ASP A  85
GLU A 249
THR A 281
None
1.46A 3p2kC-5mqzA:
undetectable
3p2kC-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 8 PHE A  43
GLU A 282
SER A 278
ARG A  44
None
1.37A 3rqlA-5mqzA:
undetectable
3rqlB-5mqzA:
undetectable
3rqlA-5mqzA:
15.18
3rqlB-5mqzA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 4 LEU A 152
GLY A  28
GLY A  30
THR A  93
None
0.90A 3si7A-5mqzA:
undetectable
3si7A-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 8 PHE A  43
GLU A 282
SER A 278
ARG A  44
None
1.38A 4capA-5mqzA:
undetectable
4capB-5mqzA:
undetectable
4capA-5mqzA:
15.18
4capB-5mqzA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 8 PHE A  43
GLU A 282
SER A 278
ARG A  44
None
1.35A 4d32A-5mqzA:
undetectable
4d32B-5mqzA:
undetectable
4d32A-5mqzA:
15.18
4d32B-5mqzA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
3 / 3 THR A 199
PRO A 201
THR A 228
None
None
TAM  A 303 (-3.9A)
0.84A 4hivD-5mqzA:
undetectable
4hivD-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 7 PHE A  43
GLU A 282
SER A 278
ARG A  44
None
1.37A 4k5jA-5mqzA:
undetectable
4k5jB-5mqzA:
undetectable
4k5jA-5mqzA:
12.85
4k5jB-5mqzA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
5 / 9 GLY A  97
PHE A  21
LEU A  26
SER A  19
GLY A  24
None
1.22A 4kqiA-5mqzA:
undetectable
4kqiA-5mqzA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 8 THR A 134
LEU A 232
VAL A 241
VAL A 191
None
0.95A 4l4bA-5mqzA:
undetectable
4l4bA-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 8 PHE A  43
GLU A 282
SER A 278
ARG A  44
None
1.35A 4v3yA-5mqzA:
undetectable
4v3yB-5mqzA:
undetectable
4v3yA-5mqzA:
15.18
4v3yB-5mqzA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 7 PHE A  43
GLU A 282
SER A 278
ARG A  44
None
1.37A 5adlA-5mqzA:
undetectable
5adlB-5mqzA:
undetectable
5adlA-5mqzA:
12.85
5adlB-5mqzA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_1
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 4 ASP A  22
GLY A  30
ASP A  29
ASP A 102
None
0.97A 5e72A-5mqzA:
undetectable
5e72A-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 7 PHE A  43
GLU A 282
SER A 278
ARG A  44
None
1.41A 5fj3A-5mqzA:
undetectable
5fj3B-5mqzA:
undetectable
5fj3A-5mqzA:
12.85
5fj3B-5mqzA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
5 / 12 ILE A 261
GLY A 262
ALA A 238
LEU A 235
VAL A 191
None
1.24A 5hw4A-5mqzA:
undetectable
5hw4A-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
5 / 12 ILE A 261
GLY A 262
ALA A 238
LEU A 235
VAL A 191
None
1.22A 5hw4C-5mqzA:
undetectable
5hw4C-5mqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 8 SER A 278
ARG A  44
PHE A  43
GLU A 282
None
1.30A 5uo7A-5mqzA:
undetectable
5uo7B-5mqzA:
undetectable
5uo7A-5mqzA:
11.88
5uo7B-5mqzA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 6 SER A 278
ARG A  44
PHE A  43
GLU A 282
None
1.39A 5uo8A-5mqzA:
undetectable
5uo8B-5mqzA:
undetectable
5uo8A-5mqzA:
12.96
5uo8B-5mqzA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 7 PHE A  43
GLU A 282
SER A 278
ARG A  44
None
1.38A 5vv7A-5mqzA:
undetectable
5vv7B-5mqzA:
undetectable
5vv7A-5mqzA:
12.85
5vv7B-5mqzA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 7 PHE A  43
GLU A 282
SER A 278
ARG A  44
None
1.36A 5vvnA-5mqzA:
undetectable
5vvnB-5mqzA:
undetectable
5vvnA-5mqzA:
12.85
5vvnB-5mqzA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 7 SER A 278
ARG A  44
PHE A  43
GLU A 282
None
1.38A 6av6A-5mqzA:
undetectable
6av6B-5mqzA:
0.0
6av6A-5mqzA:
23.17
6av6B-5mqzA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 7 SER A 278
ARG A  44
PHE A  43
GLU A 282
None
1.37A 6av7A-5mqzA:
undetectable
6av7B-5mqzA:
0.0
6av7A-5mqzA:
23.17
6av7B-5mqzA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)
5mqz PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Archaeoglobus
fulgidus)
4 / 5 GLY A 179
ASN A 178
ARG A 138
ARG A 177
None
1.37A 6dwdB-5mqzA:
undetectable
6dwdD-5mqzA:
undetectable
6dwdB-5mqzA:
undetectable
6dwdD-5mqzA:
undetectable