SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mr3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 5mr3 VITELLINE ENVELOPE
SPERM LYSIN RECEPTOR
(Haliotis
rufescens) 		4 / 5 PHE B 181
ILE B 188
MET B 226
ASN B 225
 GOL  B 901 (-4.4A)
None
None
None
 0.94A 3octA-5mr3B:
undetectable		 3octA-5mr3B:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 5mr3 VITELLINE ENVELOPE
SPERM LYSIN RECEPTOR
(Haliotis
rufescens) 		5 / 12 PHE B 192
ILE B 278
VAL B 216
MET B 207
LEU B 266
 None
 1.17A 5byjA-5mr3B:
undetectable		 5byjA-5mr3B:
16.47