SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mr5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5mr5 GDNF FAMILY RECEPTOR
ALPHA-2
(Homo
sapiens) 		4 / 7 LEU C 339
PHE C 338
MET C 305
THR C 306
 None
 1.21A 2zxwN-5mr5C:
undetectable
2zxwW-5mr5C:
undetectable		 2zxwN-5mr5C:
undetectable
2zxwW-5mr5C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 5mr5 GDNF FAMILY RECEPTOR
ALPHA-2
(Homo
sapiens) 		3 / 3 GLN C 291
PHE C 355
TYR C 217
 None
 0.96A 3ucjB-5mr5C:
undetectable		 3ucjB-5mr5C:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 5mr5 GDNF FAMILY RECEPTOR
ALPHA-2
(Homo
sapiens) 		3 / 3 GLN C 291
PHE C 355
TYR C 217
 None
 0.96A 3ucjA-5mr5C:
undetectable		 3ucjA-5mr5C:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 5mr5 GDNF FAMILY RECEPTOR
ALPHA-2
(Homo
sapiens) 		3 / 3 PHE C 208
TYR C 309
TYR C 297
 None
 1.08A 4ffwA-5mr5C:
undetectable		 4ffwA-5mr5C:
7.98