SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mrj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		3 / 3 ALA A 204
VAL A 202
TRP A 216
 None
 0.93A 1grmA-5mrjA:
undetectable		 1grmA-5mrjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		3 / 3 ALA A 204
VAL A 202
TRP A 216
 None
 0.93A 1grmB-5mrjA:
undetectable		 1grmB-5mrjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		3 / 3 TRP A 153
HIS A 201
MET A 205
 None
 0.83A 1l5qB-5mrjA:
0.4		 1l5qB-5mrjA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_D_PAUD6004_0
(PANTOTHENATE KINASE)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		5 / 10 VAL A 237
LEU A 181
LYS A 186
LEU A 194
ASN A 189
 None
 1.25A 1sq5D-5mrjA:
undetectable		 1sq5D-5mrjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		5 / 7 HIS A 215
ALA A 329
GLY A 296
ASN A 262
PHE A 107
 None
 1.21A 2c49B-5mrjA:
undetectable		 2c49B-5mrjA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		5 / 12 ALA A 303
VAL A 313
ASP A 267
GLY A 337
ILE A 335
 None
 1.18A 2dcfA-5mrjA:
undetectable		 2dcfA-5mrjA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		5 / 12 LEU A 378
LEU A  96
ILE A 335
VAL A 101
VAL A 330
 None
 1.30A 2pnjB-5mrjA:
undetectable		 2pnjB-5mrjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		3 / 3 LEU A 122
TRP A 362
TYR A 115
 None
 0.98A 3aicA-5mrjA:
3.9		 3aicA-5mrjA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		3 / 3 LEU A 122
TRP A 362
TYR A 115
 None
 1.00A 3aicB-5mrjA:
2.4		 3aicB-5mrjA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		3 / 3 LEU A 122
TRP A 362
TYR A 115
 None
 1.00A 3aicE-5mrjA:
5.0		 3aicE-5mrjA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		3 / 3 LEU A 122
TRP A 362
TYR A 115
 None
 0.97A 3aicF-5mrjA:
5.0		 3aicF-5mrjA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		3 / 3 LEU A 122
TRP A 362
TYR A 115
 None
 0.99A 3aicG-5mrjA:
3.9		 3aicG-5mrjA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RLB_B_VIBB187_1
(THIT)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		5 / 12 GLU A 327
TYR A 260
HIS A 215
GLY A 172
VAL A 218
 None
 1.30A 3rlbB-5mrjA:
undetectable		 3rlbB-5mrjA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		4 / 5 HIS A 116
THR A 123
GLU A 111
ASP A 334
 None
 1.24A 3tm4A-5mrjA:
2.2		 3tm4A-5mrjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		4 / 5 HIS A 116
THR A 123
GLU A 111
ASP A 334
 None
 1.24A 3tm4B-5mrjA:
2.2		 3tm4B-5mrjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		3 / 3 TRP A 370
VAL A 361
TRP A 362
 None
 0.95A 3zq8C-5mrjA:
undetectable
3zq8D-5mrjA:
undetectable		 3zq8C-5mrjA:
undetectable
3zq8D-5mrjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		4 / 7 GLU A 145
PHE A 151
HIS A 173
VAL A 160
 None
 1.08A 4a97D-5mrjA:
undetectable		 4a97D-5mrjA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		4 / 6 GLU A 145
PHE A 151
HIS A 173
VAL A 160
 None
 1.12A 4a97I-5mrjA:
undetectable		 4a97I-5mrjA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		3 / 3 TYR A 260
PHE A 107
ARG A 171
 None
 1.03A 4g19D-5mrjA:
undetectable		 4g19D-5mrjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		3 / 3 ASN A 119
ASP A 368
ASP A 380
 None
 0.83A 4obwD-5mrjA:
undetectable		 4obwD-5mrjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		5 / 10 ASP A 263
ALA A 272
ASP A 226
SER A 224
GLY A 227
 None
 1.41A 4xp1A-5mrjA:
undetectable		 4xp1A-5mrjA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ARF_A_SAMA1002_0
(N-LYSINE
METHYLTRANSFERASE
SMYD2)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		5 / 12 LYS A 273
GLU A 280
ASN A 283
ALA A 323
PHE A 223
 None
 1.47A 5arfA-5mrjA:
undetectable		 5arfA-5mrjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		5 / 12 VAL A 313
ASP A 267
ALA A 349
GLN A 132
GLY A 296
 None
 1.20A 5m54E-5mrjA:
undetectable		 5m54E-5mrjA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 5mrj BETA-XYLANASE
(Acremonium
chrysogenum) 		5 / 10 VAL A 219
ILE A 222
LEU A 229
GLY A 244
ALA A 246
 None
 1.02A 5mxbA-5mrjA:
undetectable		 5mxbA-5mrjA:
23.96