SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mrr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		4 / 8 GLY A 153
THR A 150
GLY A 157
GLN A 156
 None
 0.84A 1jr1B-5mrrA:
undetectable		 1jr1B-5mrrA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_1
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		4 / 4 SER A 104
SER A 147
LEU A   4
PHE A  21
 None
 1.34A 1r5lA-5mrrA:
undetectable		 1r5lA-5mrrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		4 / 8 ASP A  63
PHE A  59
SER A 144
ALA A  65
 None
 0.90A 1rqpC-5mrrA:
undetectable		 1rqpC-5mrrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		4 / 8 ASP A  63
PHE A  59
SER A 144
ALA A  65
 None
 0.90A 1rqpA-5mrrA:
undetectable		 1rqpA-5mrrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		3 / 3 ALA A  34
VAL A  32
TRP A  66
 None
 1.01A 1tkqA-5mrrA:
undetectable		 1tkqA-5mrrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		4 / 8 GLY A   5
ILE A   7
ASN A   2
GLN A  76
 None
 1.00A 2a8tB-5mrrA:
undetectable		 2a8tB-5mrrA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		4 / 8 ASP A  63
PHE A  59
SER A 144
ALA A  65
 None
 0.91A 2v7uA-5mrrA:
undetectable		 2v7uA-5mrrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		5 / 12 GLY A  20
GLY A 145
ILE A  87
GLY A   6
GLY A   5
 None
 1.10A 3axzA-5mrrA:
undetectable		 3axzA-5mrrA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		3 / 3 GLY A 146
GLY A   5
GLY A  20
 None
 0.43A 3bogC-5mrrA:
undetectable		 3bogC-5mrrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		5 / 9 LEU A 189
GLY A 157
ASP A  63
VAL A  19
ILE A 188
 None
 0.95A 3oxvA-5mrrA:
undetectable		 3oxvA-5mrrA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		5 / 9 LEU A 189
GLY A 157
ASP A  63
VAL A  19
ILE A 188
 None
 0.99A 3oxvC-5mrrA:
undetectable		 3oxvC-5mrrA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_D_EVPD1_1
(DNA TOPOISOMERASE
2-BETA)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		4 / 5 GLY A 140
ASP A 143
ARG A 111
GLN A 134
 None
 1.49A 3qx3B-5mrrA:
undetectable		 3qx3B-5mrrA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		4 / 5 SER A 147
SER A  80
VAL A  79
GLY A  20
 None
 1.04A 3rxhA-5mrrA:
9.1		 3rxhA-5mrrA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		5 / 12 TYR A  82
GLY A 146
GLY A   6
GLU A   8
ALA A  34
 None
 1.10A 3vywA-5mrrA:
undetectable		 3vywA-5mrrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		5 / 12 ASN A   2
GLY A   5
ASN A  81
GLY A 153
SER A  22
 None
 1.29A 4obwC-5mrrA:
undetectable		 4obwC-5mrrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		5 / 12 GLY A   5
SER A  80
ASN A   2
GLY A  30
SER A  18
 None
 0.97A 4obwC-5mrrA:
undetectable		 4obwC-5mrrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		5 / 12 GLY A  20
GLY A 145
ILE A  87
GLY A   6
GLY A   5
 None
 1.05A 4yvgA-5mrrA:
undetectable		 4yvgA-5mrrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		5 / 12 LEU A 196
ALA A 155
SER A 147
ILE A 188
LEU A 132
 None
 1.19A 5hbsA-5mrrA:
undetectable		 5hbsA-5mrrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		5 / 12 LEU A 196
ALA A 155
SER A 147
ILE A 188
LEU A 132
 None
 1.19A 5ljbA-5mrrA:
undetectable		 5ljbA-5mrrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		5 / 12 LEU A 196
ALA A 155
SER A 147
ILE A 188
LEU A 132
 None
 1.23A 5ljcA-5mrrA:
undetectable		 5ljcA-5mrrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		5 / 12 GLY A  20
GLY A 145
ILE A  87
GLY A   6
GLY A   5
 None
 1.05A 5wyqA-5mrrA:
undetectable		 5wyqA-5mrrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		5 / 11 GLY A 168
GLN A 165
ARG A 111
ARG A 178
GLY A 162
 None
 1.22A 5x19A-5mrrA:
undetectable
5x19B-5mrrA:
undetectable
5x19T-5mrrA:
undetectable		 5x19A-5mrrA:
undetectable
5x19B-5mrrA:
undetectable
5x19T-5mrrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 5mrr LYTIC ENDOPEPTIDASE
PREPROENZYME
(Lysobacter
sp.
XL1) 		5 / 12 HIS A  36
VAL A  58
ASP A  63
GLY A 142
SER A 144
 None
 1.07A 6c2mC-5mrrA:
11.6		 6c2mC-5mrrA:
25.00