SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ms7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 5ms7 LEGIONELLA
PNEUMOPHILA EFFECTOR
PROTEIN RAVZ
(Legionella
pneumophila) 		4 / 6 ILE A 281
ASN A 248
SER A 198
ASN A 257
 None
 1.27A 1h7xC-5ms7A:
undetectable		 1h7xC-5ms7A:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 5ms7 LEGIONELLA
PNEUMOPHILA EFFECTOR
PROTEIN RAVZ
(Legionella
pneumophila) 		4 / 6 ILE A 281
ASN A 248
SER A 198
ASN A 257
 None
 1.27A 1h7xD-5ms7A:
undetectable		 1h7xD-5ms7A:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ms7 LEGIONELLA
PNEUMOPHILA EFFECTOR
PROTEIN RAVZ
(Legionella
pneumophila) 		4 / 7 LYS A 389
LEU A 390
GLN A 386
LEU A 418
 None
 1.07A 2dysP-5ms7A:
2.4
2dysW-5ms7A:
undetectable		 2dysP-5ms7A:
17.36
2dysW-5ms7A:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 5ms7 LEGIONELLA
PNEUMOPHILA EFFECTOR
PROTEIN RAVZ
(Legionella
pneumophila) 		5 / 11 LEU A  71
LEU A  74
ILE A 301
ALA A  81
LEU A 293
 None
 0.97A 2q72A-5ms7A:
undetectable		 2q72A-5ms7A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 5ms7 LEGIONELLA
PNEUMOPHILA EFFECTOR
PROTEIN RAVZ
(Legionella
pneumophila) 		5 / 12 LEU A 410
LEU A 413
GLY A 414
VAL A 422
MET A 398
 None
 1.48A 2q7lA-5ms7A:
undetectable		 2q7lA-5ms7A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 5ms7 LEGIONELLA
PNEUMOPHILA EFFECTOR
PROTEIN RAVZ
(Legionella
pneumophila) 		5 / 12 LEU A  71
LEU A  74
ILE A 301
ALA A  81
LEU A 293
 None
 0.94A 2qb4A-5ms7A:
2.6		 2qb4A-5ms7A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 5ms7 LEGIONELLA
PNEUMOPHILA EFFECTOR
PROTEIN RAVZ
(Legionella
pneumophila) 		5 / 11 LEU A  71
LEU A  74
ILE A 301
ALA A  81
LEU A 293
 None
 0.99A 2qjuA-5ms7A:
undetectable		 2qjuA-5ms7A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5ms7 LEGIONELLA
PNEUMOPHILA EFFECTOR
PROTEIN RAVZ
(Legionella
pneumophila) 		4 / 7 TYR A 184
SER A 183
GLN A 110
ILE A 146
 None
 1.25A 2xz5A-5ms7A:
undetectable
2xz5B-5ms7A:
undetectable		 2xz5A-5ms7A:
18.79
2xz5B-5ms7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_1
(PROTEASE)		 5ms7 LEGIONELLA
PNEUMOPHILA EFFECTOR
PROTEIN RAVZ
(Legionella
pneumophila) 		5 / 10 LEU A 413
VAL A 422
ILE A 382
GLY A 371
ILE A 370
 None
 1.01A 3el5A-5ms7A:
undetectable		 3el5A-5ms7A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 5ms7 LEGIONELLA
PNEUMOPHILA EFFECTOR
PROTEIN RAVZ
(Legionella
pneumophila) 		5 / 12 LEU A  71
LEU A  74
ILE A 301
ALA A  81
LEU A 293
 None
 0.96A 3gwvA-5ms7A:
undetectable		 3gwvA-5ms7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5ms7 LEGIONELLA
PNEUMOPHILA EFFECTOR
PROTEIN RAVZ
(Legionella
pneumophila) 		5 / 10 PHE A  75
TYR A  72
THR A 181
VAL A 269
ILE A 270
 None
 1.17A 4jx1B-5ms7A:
undetectable		 4jx1B-5ms7A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA408_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 5ms7 LEGIONELLA
PNEUMOPHILA EFFECTOR
PROTEIN RAVZ
(Legionella
pneumophila) 		4 / 6 THR A 181
PRO A 193
PHE A 163
PHE A 242
 None
 1.21A 4kf9A-5ms7A:
undetectable		 4kf9A-5ms7A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 5ms7 LEGIONELLA
PNEUMOPHILA EFFECTOR
PROTEIN RAVZ
(Legionella
pneumophila) 		5 / 11 LEU A 413
VAL A 422
ILE A 382
GLY A 371
ILE A 370
 None
 0.95A 4njtA-5ms7A:
undetectable		 4njtA-5ms7A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 5ms7 LEGIONELLA
PNEUMOPHILA EFFECTOR
PROTEIN RAVZ
(Legionella
pneumophila) 		5 / 12 LEU A  68
ASP A 197
LEU A 224
PHE A 163
HIS A 176
 None
 1.32A 5dv4A-5ms7A:
undetectable		 5dv4A-5ms7A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 5ms7 LEGIONELLA
PNEUMOPHILA EFFECTOR
PROTEIN RAVZ
(Legionella
pneumophila) 		4 / 7 VAL A  59
GLU A 302
ASN A 248
ILE A 281
 None
 0.93A 5jh7C-5ms7A:
undetectable		 5jh7C-5ms7A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5ms7 LEGIONELLA
PNEUMOPHILA EFFECTOR
PROTEIN RAVZ
(Legionella
pneumophila) 		5 / 12 ASP A 236
LEU A 180
LEU A 143
ALA A 231
LEU A 239
 None
 1.08A 5nd7B-5ms7A:
undetectable		 5nd7B-5ms7A:
22.12