SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mse'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		4 / 6 LEU A  44
GLU A  32
THR A 118
LEU A  42
 CRO  A  66 ( 4.8A)
None
None
None
 1.24A 1etb2-5mseA:
undetectable		 1etb2-5mseA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		3 / 3 ASN A 170
LEU A 141
HIS A 169
 IMD  A 303 (-3.6A)
None
NA  A 301 (-4.1A)
 0.87A 2q6fB-5mseA:
undetectable		 2q6fB-5mseA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 12 LEU A  44
LEU A  42
ILE A  14
ALA A  37
PHE A  71
 CRO  A  66 ( 4.8A)
None
None
None
None
 1.17A 2qb4A-5mseA:
undetectable		 2qb4A-5mseA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		4 / 5 VAL A 112
VAL A 111
THR A  63
ARG A 113
 CRO  A  66 ( 4.9A)
None
None
None
 1.17A 3bjwA-5mseA:
undetectable		 3bjwA-5mseA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 9 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
CRO  A  66 ( 4.9A)
CRO  A  66 ( 3.7A)
None
None
 1.18A 3t3rB-5mseA:
undetectable		 3t3rB-5mseA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 9 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
CRO  A  66 ( 4.9A)
CRO  A  66 ( 3.7A)
None
None
 1.21A 3t3rC-5mseA:
undetectable		 3t3rC-5mseA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 10 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
CRO  A  66 ( 4.9A)
CRO  A  66 ( 3.7A)
None
None
 1.17A 3t3rD-5mseA:
undetectable		 3t3rD-5mseA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		4 / 6 THR A 128
ASN A  23
GLY A  24
ASP A  21
 None
 1.18A 3w9tE-5mseA:
undetectable		 3w9tE-5mseA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		4 / 7 ASP A  19
THR A 108
SER A  28
PHE A  27
 None
 1.03A 4ac9C-5mseA:
undetectable		 4ac9C-5mseA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		4 / 6 VAL A  55
LEU A  53
LEU A 125
PHE A 165
 None
None
None
CRO  A  66 ( 4.4A)
 0.91A 4o1zA-5mseA:
undetectable		 4o1zA-5mseA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLE_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		6 / 11 ALA A 110
LEU A  64
ILE A  14
LEU A  42
TYR A  92
THR A 108
 None
CRO  A  66 ( 4.3A)
None
None
None
None
 1.43A 4qleB-5mseA:
undetectable		 4qleB-5mseA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		6 / 12 ALA A 110
LEU A  64
ILE A  14
LEU A  42
TYR A  92
THR A 108
 None
CRO  A  66 ( 4.3A)
None
None
None
None
 1.40A 4qlgA-5mseA:
undetectable		 4qlgA-5mseA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		6 / 12 ALA A 110
LEU A  64
ILE A  14
LEU A  42
TYR A  92
THR A 108
 None
CRO  A  66 ( 4.3A)
None
None
None
None
 1.39A 4qlgB-5mseA:
undetectable		 4qlgB-5mseA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		6 / 12 ALA A 110
LEU A  64
ILE A  14
LEU A  42
TYR A  92
THR A 108
 None
CRO  A  66 ( 4.3A)
None
None
None
None
 1.45A 5eajA-5mseA:
undetectable		 5eajA-5mseA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		4 / 8 GLU A 176
HIS A 148
MET A 218
LEU A  42
 None
CRO  A  66 ( 3.8A)
None
None
 1.06A 5y2tB-5mseA:
undetectable		 5y2tB-5mseA:
undetectable