SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5msn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 5msn DCC1 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 8 VAL A 208
ASN A 236
GLY A 169
LEU A 180
 None
 0.89A 1dzmA-5msnA:
undetectable		 1dzmA-5msnA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 5msn DCC1 PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 PHE A 223
TYR A 125
PRO A 225
 None
 0.97A 1mcnA-5msnA:
undetectable
1mcnB-5msnA:
undetectable
1mcnP-5msnA:
undetectable		 1mcnA-5msnA:
21.74
1mcnB-5msnA:
21.74
1mcnP-5msnA:
5.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 5msn DCC1 PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 GLU A 232
TRP A 250
LYS A 134
 None
 1.38A 1qu2A-5msnA:
undetectable		 1qu2A-5msnA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5msn DCC1 PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 212
SER A 171
GLU A 229
 None
 0.92A 3s8pA-5msnA:
undetectable		 3s8pA-5msnA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5msn DCC1 PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 THR A 375
VAL A 377
GLU A 342
 None
 0.70A 3v4tA-5msnA:
undetectable
3v4tD-5msnA:
undetectable		 3v4tA-5msnA:
21.99
3v4tD-5msnA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR5_A_SRYA1860_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 5msn DCC1 PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 326
PRO A 325
LYS A 364
 None
 1.41A 4dr5L-5msnA:
undetectable		 4dr5L-5msnA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR6_A_SRYA1956_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 5msn DCC1 PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 326
PRO A 325
LYS A 364
 None
 1.35A 4dr6L-5msnA:
undetectable		 4dr6L-5msnA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUZ_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 5msn DCC1 PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 326
PRO A 325
LYS A 364
 None
 1.34A 4duzL-5msnA:
undetectable		 4duzL-5msnA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV7_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 5msn DCC1 PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 326
PRO A 325
LYS A 364
 None
 1.11A 4dv7L-5msnA:
undetectable		 4dv7L-5msnA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGZ_A_SPRA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5msn DCC1 PROTEIN
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 266
ILE A 316
ILE A 277
GLU A 279
PHE A 280
 None
 1.24A 5igzA-5msnA:
undetectable		 5igzA-5msnA:
24.01