SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mso'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 11 GLU A 800
LEU A 843
LEU A 809
ALA A 795
GLY A 791
 None
None
None
None
NAP  A1201 (-3.8A)
 1.28A 1cmaA-5msoA:
undetectable
1cmaB-5msoA:
undetectable		 1cmaA-5msoA:
6.81
1cmaB-5msoA:
6.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 10 ALA A 795
GLY A 791
GLU A 800
LEU A 843
LEU A 809
 None
NAP  A1201 (-3.8A)
None
None
None
 1.23A 1cmcA-5msoA:
undetectable
1cmcB-5msoA:
undetectable		 1cmcA-5msoA:
6.81
1cmcB-5msoA:
6.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_B_SAMB105_0
(MET REPRESSOR)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 10 GLU A 800
LEU A 843
LEU A 809
ALA A 795
GLY A 791
 None
None
None
None
NAP  A1201 (-3.8A)
 1.23A 1cmcA-5msoA:
undetectable
1cmcB-5msoA:
undetectable		 1cmcA-5msoA:
6.81
1cmcB-5msoA:
6.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_C_HISC450_0
(HISTIDYL-TRNA
SYNTHETASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 12 THR A 828
LEU A 796
GLY A 791
GLY A 788
ALA A 786
 None
None
NAP  A1201 (-3.8A)
NAP  A1201 (-3.2A)
None
 1.31A 1httC-5msoA:
undetectable		 1httC-5msoA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_D_HISD450_0
(HISTIDYL-TRNA
SYNTHETASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 12 THR A 828
LEU A 796
GLY A 791
GLY A 788
ALA A 786
 None
None
NAP  A1201 (-3.8A)
NAP  A1201 (-3.2A)
None
 1.27A 1httD-5msoA:
undetectable		 1httD-5msoA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		4 / 5 SER A 920
THR A 921
GLU A 964
GLY A 963
 None
 1.20A 1icrA-5msoA:
undetectable
1icrB-5msoA:
undetectable		 1icrA-5msoA:
14.26
1icrB-5msoA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		4 / 5 GLU A 964
GLY A 963
SER A 920
THR A 921
 None
 1.19A 1icrA-5msoA:
undetectable
1icrB-5msoA:
undetectable		 1icrA-5msoA:
14.26
1icrB-5msoA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		4 / 5 SER A 920
THR A 921
GLU A 964
GLY A 963
 None
 1.19A 1icvC-5msoA:
undetectable
1icvD-5msoA:
undetectable		 1icvC-5msoA:
14.26
1icvD-5msoA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		4 / 5 GLU A 964
GLY A 963
SER A 920
THR A 921
 None
 1.19A 1icvC-5msoA:
undetectable
1icvD-5msoA:
undetectable		 1icvC-5msoA:
14.26
1icvD-5msoA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		4 / 5 GLU A 964
GLY A 963
SER A 920
THR A 921
 None
 1.18A 1kqbA-5msoA:
undetectable
1kqbB-5msoA:
undetectable		 1kqbA-5msoA:
12.47
1kqbB-5msoA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 12 ALA A 795
GLY A 791
GLU A 800
LEU A 843
LEU A 809
 None
NAP  A1201 (-3.8A)
None
None
None
 1.23A 1mj2A-5msoA:
undetectable
1mj2B-5msoA:
undetectable		 1mj2A-5msoA:
6.72
1mj2B-5msoA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 12 ALA A 795
GLY A 791
GLU A 800
LEU A 843
LEU A 809
 None
NAP  A1201 (-3.8A)
None
None
None
 1.29A 1mj2C-5msoA:
undetectable
1mj2D-5msoA:
undetectable		 1mj2C-5msoA:
6.72
1mj2D-5msoA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 12 ALA A 795
GLY A 791
GLU A 800
LEU A 843
LEU A 809
 None
NAP  A1201 (-3.8A)
None
None
None
 1.25A 1mjoC-5msoA:
undetectable
1mjoD-5msoA:
undetectable		 1mjoC-5msoA:
6.72
1mjoD-5msoA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 11 GLU A 800
LEU A 843
LEU A 809
ALA A 795
GLY A 791
 None
None
None
None
NAP  A1201 (-3.8A)
 1.33A 1mjqA-5msoA:
undetectable
1mjqB-5msoA:
undetectable		 1mjqA-5msoA:
6.72
1mjqB-5msoA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 10 GLU A 800
LEU A 843
LEU A 809
ALA A 795
GLY A 791
 None
None
None
None
NAP  A1201 (-3.8A)
 1.27A 1mjqC-5msoA:
undetectable
1mjqD-5msoA:
undetectable		 1mjqC-5msoA:
6.72
1mjqD-5msoA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 11 GLU A 800
LEU A 843
LEU A 809
ALA A 795
GLY A 791
 None
None
None
None
NAP  A1201 (-3.8A)
 1.26A 1mjqI-5msoA:
undetectable
1mjqJ-5msoA:
undetectable		 1mjqI-5msoA:
6.72
1mjqJ-5msoA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		4 / 6 PRO A1037
ALA A1042
GLU A 797
GLU A1043
 None
 1.26A 1qhyA-5msoA:
2.6		 1qhyA-5msoA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLS_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 12 SER A 943
ILE A 939
TYR A1059
VAL A 980
ALA A 979
 None
 1.08A 1tlsA-5msoA:
undetectable		 1tlsA-5msoA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TSN_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 12 SER A 943
ILE A 939
TYR A1059
VAL A 980
ALA A 979
 None
 1.09A 1tsnA-5msoA:
undetectable		 1tsnA-5msoA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		6 / 12 ARG A 801
ASP A1150
ASP A1152
VAL A1142
ILE A1153
ILE A1147
 None
 1.21A 2avoB-5msoA:
undetectable		 2avoB-5msoA:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		6 / 12 ARG A 801
ASP A1150
ASP A1152
VAL A1142
ILE A1153
ILE A1147
 None
 1.26A 2bpxB-5msoA:
undetectable		 2bpxB-5msoA:
5.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		4 / 4 LEU A 782
ARG A 864
LEU A 862
ALA A 871
 None
 1.21A 3b9mA-5msoA:
undetectable		 3b9mA-5msoA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		4 / 5 ALA A1050
PRO A 977
TYR A 916
ALA A 908
 None
 1.41A 3twpD-5msoA:
2.8		 3twpD-5msoA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		4 / 7 ALA A1044
ILE A1045
ARG A 801
GLY A1049
 None
 0.86A 3v4tH-5msoA:
undetectable		 3v4tH-5msoA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		3 / 3 ARG A 968
ARG A 982
ASP A 936
 None
 0.86A 3wipG-5msoA:
undetectable
3wipH-5msoA:
undetectable		 3wipG-5msoA:
11.75
3wipH-5msoA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		4 / 8 PHE A1056
HIS A 971
GLU A 969
ILE A 939
 None
 1.36A 4cx7A-5msoA:
undetectable
4cx7B-5msoA:
undetectable		 4cx7A-5msoA:
16.19
4cx7B-5msoA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_H_FOLH703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 9 VAL A 749
ALA A 751
LYS A 960
SER A 957
PHE A 933
 None
None
NAP  A1201 (-2.9A)
None
None
 1.49A 4eilH-5msoA:
undetectable		 4eilH-5msoA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		4 / 5 PHE A1074
TYR A1033
THR A1003
ILE A1161
 None
 1.16A 4jx1E-5msoA:
undetectable		 4jx1E-5msoA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_I_IPHI101_0
(INSULIN)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 12 LEU A 909
ILE A 877
LEU A 976
LEU A 967
ALA A 970
 None
 0.98A 4p65B-5msoA:
undetectable
4p65D-5msoA:
undetectable
4p65I-5msoA:
undetectable
4p65J-5msoA:
undetectable		 4p65B-5msoA:
3.16
4p65D-5msoA:
3.16
4p65I-5msoA:
1.97
4p65J-5msoA:
3.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 12 GLY A 923
TYR A 956
ASP A1000
ALA A 882
MET A1062
 None
NAP  A1201 (-4.7A)
None
NAP  A1201 (-3.6A)
None
 1.05A 5igvA-5msoA:
undetectable		 5igvA-5msoA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		4 / 6 TYR A1033
ASP A1000
TYR A1121
TYR A 952
 None
 1.37A 5igyA-5msoA:
undetectable		 5igyA-5msoA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 12 ILE A1006
VAL A1156
ILE A1085
ALA A1010
VAL A1075
 None
 0.92A 5n0sA-5msoA:
undetectable		 5n0sA-5msoA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 12 ILE A1006
VAL A1156
ILE A1085
ALA A1010
VAL A1075
 None
 0.94A 5n0wB-5msoA:
undetectable		 5n0wB-5msoA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 12 ILE A1006
VAL A1156
ILE A1085
ALA A1010
VAL A1075
 None
 0.92A 5n0xA-5msoA:
undetectable		 5n0xA-5msoA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 12 ILE A1006
VAL A1156
ILE A1085
ALA A1010
VAL A1075
 None
 0.92A 5n4iA-5msoA:
undetectable		 5n4iA-5msoA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 12 ILE A1161
ASP A1072
LEU A1071
GLY A1070
ALA A1015
 None
 1.23A 5x5qB-5msoA:
undetectable		 5x5qB-5msoA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 10 ILE A 877
ILE A1041
ALA A1042
LEU A 794
ALA A 795
 None
 1.20A 5zjiB-5msoA:
undetectable		 5zjiB-5msoA:
5.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		4 / 7 ILE A1006
PHE A1098
LEU A1009
ILE A1069
 None
 0.77A 6b5vA-5msoA:
undetectable
6b5vC-5msoA:
undetectable		 6b5vA-5msoA:
5.42
6b5vC-5msoA:
5.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		4 / 7 ILE A1006
PHE A1098
LEU A1009
ILE A1069
 None
 0.77A 6b5vC-5msoA:
undetectable
6b5vD-5msoA:
undetectable		 6b5vC-5msoA:
5.42
6b5vD-5msoA:
5.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		4 / 7 ILE A1006
PHE A1098
LEU A1009
ILE A1069
 None
 0.78A 6b5vB-5msoA:
undetectable
6b5vD-5msoA:
undetectable		 6b5vB-5msoA:
5.42
6b5vD-5msoA:
5.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 11 LEU A1071
ILE A1085
PHE A1002
ILE A1006
ILE A1161
 None
 0.88A 6ebzA-5msoA:
undetectable		 6ebzA-5msoA:
6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 11 LEU A1071
ILE A1085
PHE A1002
ILE A1006
ILE A1161
 None
 0.90A 6ebzB-5msoA:
undetectable		 6ebzB-5msoA:
6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 11 LEU A1071
ILE A1085
PHE A1002
ILE A1006
ILE A1161
 None
 0.90A 6ebzC-5msoA:
undetectable		 6ebzC-5msoA:
6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 11 LEU A1071
ILE A1085
PHE A1002
ILE A1006
ILE A1161
 None
 0.89A 6ebzD-5msoA:
undetectable		 6ebzD-5msoA:
6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 11 LEU A1071
ILE A1085
PHE A1002
ILE A1006
ILE A1161
 None
 0.93A 6gp2A-5msoA:
undetectable		 6gp2A-5msoA:
5.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 5mso CARBOXYLIC ACID
REDUCTASE
(Mycobacterium
marinum) 		5 / 11 LEU A1071
ILE A1085
PHE A1002
ILE A1006
ILE A1161
 None
 0.92A 6gp2B-5msoA:
undetectable		 6gp2B-5msoA:
5.87