SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mt2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 5mt2 BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 113
ALA A 170
ASP A 118
GLY A 168
 GOL  A 402 (-3.5A)
None
None
None
 0.94A 1e7cA-5mt2A:
undetectable		 1e7cA-5mt2A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)		 5mt2 BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 GLU A 154
ALA A 163
LEU A 165
ALA A 160
GLY A 157
 None
 1.27A 1mjqG-5mt2A:
undetectable
1mjqH-5mt2A:
undetectable		 1mjqG-5mt2A:
14.44
1mjqH-5mt2A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5mt2 BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLN A 205
ALA A 245
ARG A 241
ASN A 259
 None
 1.11A 1t9wA-5mt2A:
undetectable		 1t9wA-5mt2A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 5mt2 BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 358
TYR A  79
ALA A 360
ALA A 350
TYR A 327
 None
 1.37A 2avdB-5mt2A:
undetectable		 2avdB-5mt2A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5mt2 BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 MET A  74
ILE A  60
PRO A 126
GLY A 123
 None
 1.02A 2pnjB-5mt2A:
undetectable		 2pnjB-5mt2A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 5mt2 BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 4 GLY A 123
TYR A 150
GLY A 152
ASP A 118
 None
 0.94A 3kl3A-5mt2A:
undetectable		 3kl3A-5mt2A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 5mt2 BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LEU A 320
ASP A 319
ALA A 318
TYR A  38
 None
 1.21A 3rodD-5mt2A:
undetectable		 3rodD-5mt2A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5mt2 BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 PRO A 323
ASP A 328
GLU A 329
 None
 0.81A 3v4tC-5mt2A:
undetectable		 3v4tC-5mt2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 5mt2 BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 TYR A 112
ARG A 108
SER A 111
 None
 0.98A 4dr2I-5mt2A:
undetectable
4dr2J-5mt2A:
undetectable		 4dr2I-5mt2A:
16.23
4dr2J-5mt2A:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_2
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 5mt2 BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 LEU A 101
VAL A  65
TYR A 345
ARG A 108
 None
 0.92A 4r7iA-5mt2A:
undetectable		 4r7iA-5mt2A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5mt2 BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 HIS A 232
GLU A 234
TRP A 199
 None
 1.24A 5odiD-5mt2A:
undetectable		 5odiD-5mt2A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_1
(CARNOSINE
N-METHYLTRANSFERASE)		 5mt2 BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 GLN A 198
ARG A 255
TYR A 226
ASP A 236
 None
 1.19A 5yf0A-5mt2A:
undetectable		 5yf0A-5mt2A:
20.71