SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mtv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 6 PHE A  58
LEU A  37
VAL A  36
ASP A  57
 None
 1.00A 1dz4A-5mtvA:
undetectable		 1dz4A-5mtvA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 6 ASN A 137
ALA A 134
GLY A 132
TYR A 172
 None
 1.14A 1l5qA-5mtvA:
undetectable		 1l5qA-5mtvA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 6 ASN A 137
ALA A 134
GLY A 132
TYR A 172
 None
 1.15A 1l5qB-5mtvA:
undetectable		 1l5qB-5mtvA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 6 ASN A 137
ALA A 134
GLY A 132
TYR A 172
 None
 1.14A 1l7xA-5mtvA:
undetectable		 1l7xA-5mtvA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		5 / 10 LEU A 377
ALA A 307
ALA A 311
LEU A 345
ASP A 386
 None
 1.20A 1rlbE-5mtvA:
undetectable		 1rlbE-5mtvA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 7 PHE A  58
LEU A  37
VAL A  36
ASP A  57
 None
 1.05A 1t87A-5mtvA:
undetectable		 1t87A-5mtvA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		5 / 9 PHE A 131
PHE A 100
LEU A  65
PHE A 135
LEU A 178
 None
 1.29A 1wrkA-5mtvA:
undetectable
1wrkB-5mtvA:
undetectable		 1wrkA-5mtvA:
10.33
1wrkB-5mtvA:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 7 PHE A 131
PHE A 100
LEU A  65
PHE A 135
 None
 1.18A 1wrlE-5mtvA:
undetectable		 1wrlE-5mtvA:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 8 PHE A 210
ALA A 182
LEU A  65
ASP A 173
 None
 1.11A 2bxkA-5mtvA:
undetectable		 2bxkA-5mtvA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		5 / 12 ALA A 209
PHE A 174
ALA A 182
VAL A  67
GLY A  68
 None
 1.14A 2ve3B-5mtvA:
undetectable		 2ve3B-5mtvA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 5 ASN A 137
ALA A 134
GLY A 132
TYR A 172
 None
 1.14A 3bcrA-5mtvA:
undetectable		 3bcrA-5mtvA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 6 ASN A 137
ALA A 134
GLY A 132
TYR A 172
 None
 1.13A 3dd1A-5mtvA:
undetectable		 3dd1A-5mtvA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 6 ASN A 137
ALA A 134
GLY A 132
TYR A 172
 None
 1.15A 3ddsA-5mtvA:
undetectable		 3ddsA-5mtvA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 6 ASN A 137
ALA A 134
GLY A 132
TYR A 172
 None
 1.14A 3ddsB-5mtvA:
undetectable		 3ddsB-5mtvA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 6 ASN A 137
ALA A 134
GLY A 132
TYR A 172
 None
 1.15A 3ddwA-5mtvA:
undetectable		 3ddwA-5mtvA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 6 ASN A 137
ALA A 134
GLY A 132
TYR A 172
 None
 1.15A 3ddwB-5mtvA:
undetectable		 3ddwB-5mtvA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 5 VAL A 235
LEU A 239
ILE A 257
ALA A 224
 None
 0.95A 3n8yB-5mtvA:
undetectable		 3n8yB-5mtvA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		3 / 3 LYS A 196
SER A 200
GLN A  69
 None
 1.14A 3si7A-5mtvA:
undetectable		 3si7A-5mtvA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 6 PHE A  58
LEU A  37
VAL A  36
ASP A  57
 None
 1.01A 4g3rB-5mtvA:
undetectable		 4g3rB-5mtvA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 4 LEU A 306
ILE A 313
HIS A 310
VAL A 309
 None
 1.08A 4xyzA-5mtvA:
undetectable		 4xyzA-5mtvA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		3 / 3 VAL A 185
SER A 157
MET A 140
 None
 0.80A 5ikqA-5mtvA:
undetectable		 5ikqA-5mtvA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 6 GLY A  73
THR A  72
SER A  71
ASN A 222
 AGS  A1000 (-3.1A)
None
AGS  A1000 (-3.0A)
AGS  A1000 (-3.2A)
 0.80A 5k4pA-5mtvA:
undetectable		 5k4pA-5mtvA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		5 / 12 GLN A  69
VAL A 219
VAL A 235
ALA A 238
LEU A 239
 None
 1.08A 5kocA-5mtvA:
undetectable		 5kocA-5mtvA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 7 THR A  72
LEU A  81
VAL A 103
GLN A  84
 None
 1.03A 5tudA-5mtvA:
2.1		 5tudA-5mtvA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 5mtv EH DOMAIN-CONTAINING
PROTEIN 4
(Mus
musculus) 		4 / 4 PHE A  48
LEU A 345
LEU A 338
VAL A 309
 None
 1.09A 5xxiA-5mtvA:
undetectable		 5xxiA-5mtvA:
23.54