SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mu5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 8 SER A 506
VAL A 290
ASN A 313
ASP A 285
 None
 1.07A 1hwkA-5mu5A:
undetectable		 1hwkA-5mu5A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 8 SER A 506
VAL A 290
ASN A 313
ASP A 285
 None
 1.07A 1hwkC-5mu5A:
undetectable		 1hwkC-5mu5A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 8 SER A 506
VAL A 290
ASN A 313
ASP A 285
 None
 1.05A 1hwkD-5mu5A:
undetectable		 1hwkD-5mu5A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 8 THR A 394
GLY A 304
THR A 305
ALA A 306
 None
SO4  A 701 (-3.3A)
SO4  A 701 (-3.1A)
None
 0.53A 2a1hA-5mu5A:
undetectable
2a1hB-5mu5A:
undetectable		 2a1hA-5mu5A:
21.69
2a1hB-5mu5A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 12 ALA A 215
LEU A 135
ILE A 149
THR A 163
TYR A  57
 None
 1.05A 2cd2A-5mu5A:
undetectable		 2cd2A-5mu5A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_SAMA201_0
(UPF0066 PROTEIN
AF_0241)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 12 TYR A 216
GLY A 128
LEU A 129
LEU A 220
SER A 218
 None
 1.35A 2nv4A-5mu5A:
undetectable		 2nv4A-5mu5A:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 5 LEU A 579
LEU A 580
LEU A 178
MET A 599
 None
 1.11A 2oaxF-5mu5A:
undetectable		 2oaxF-5mu5A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 6 VAL A 496
PHE A 459
PRO A 503
THR A 501
 None
PG4  A 705 (-4.6A)
None
None
 1.12A 2q6oB-5mu5A:
undetectable		 2q6oB-5mu5A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1353_1
(PROSTAGLANDIN
REDUCTASE 2)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 9 GLU A 151
VAL A 150
MET A  26
PHE A 154
GLU A 186
 None
 1.48A 2w98A-5mu5A:
5.4		 2w98A-5mu5A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 4 ARG A  31
GLY A  27
GLU A  28
SER A 162
 None
 1.05A 2xctS-5mu5A:
undetectable
2xctU-5mu5A:
undetectable		 2xctS-5mu5A:
23.72
2xctU-5mu5A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 12 ASP A  48
GLY A  58
ASP A  44
ILE A  65
THR A 163
 None
 0.93A 3el5B-5mu5A:
undetectable		 3el5B-5mu5A:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 4 ARG A 478
ASP A 415
GLY A 279
THR A 392
 None
 1.29A 3k4vB-5mu5A:
undetectable		 3k4vB-5mu5A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 12 ASP A  48
GLY A  58
ASP A  44
ILE A  65
THR A 163
 None
 0.85A 3tkgC-5mu5A:
undetectable		 3tkgC-5mu5A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 7 ALA A 198
ILE A 199
HIS A 123
GLY A 146
 None
 0.97A 3v4tH-5mu5A:
undetectable		 3v4tH-5mu5A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 5 LEU A 554
ALA A 558
MET A 578
PHE A 629
 None
 1.34A 3vasB-5mu5A:
undetectable		 3vasB-5mu5A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 5 PHE A 629
LEU A 579
GLY A 596
VAL A  94
 None
 1.00A 3wrkD-5mu5A:
undetectable		 3wrkD-5mu5A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 12 GLY A  45
PRO A  59
GLY A  60
GLY A  61
VAL A  40
 None
 0.91A 4b17A-5mu5A:
3.2		 4b17A-5mu5A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		3 / 3 LYS A  95
TYR A  99
ARG A  96
 None
 1.27A 4gc9A-5mu5A:
undetectable		 4gc9A-5mu5A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 7 LEU A 127
ALA A 223
LEU A 221
SER A 218
 None
 0.85A 4iklA-5mu5A:
undetectable
4iklB-5mu5A:
undetectable		 4iklA-5mu5A:
11.99
4iklB-5mu5A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 8 LEU A 127
ALA A 223
LEU A 221
SER A 218
 None
 0.86A 4iklA-5mu5A:
undetectable
4iklB-5mu5A:
undetectable		 4iklA-5mu5A:
11.99
4iklB-5mu5A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		3 / 3 TYR A 367
ARG A 369
SER A 350
 None
 0.87A 4khpI-5mu5A:
undetectable
4khpJ-5mu5A:
undetectable		 4khpI-5mu5A:
13.77
4khpJ-5mu5A:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		3 / 3 ARG A 356
GLU A 247
ARG A 331
 None
 0.97A 4mwvA-5mu5A:
undetectable		 4mwvA-5mu5A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 12 GLY A 457
GLY A 461
ASN A 458
THR A 472
GLY A 417
 None
CL  A 703 ( 3.7A)
None
None
None
 1.16A 4n48A-5mu5A:
undetectable		 4n48A-5mu5A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 7 SER A 162
ARG A  31
GLY A  27
GLU A  28
 None
 0.80A 5btaA-5mu5A:
undetectable
5btaC-5mu5A:
undetectable
5btaD-5mu5A:
undetectable		 5btaA-5mu5A:
22.13
5btaC-5mu5A:
22.13
5btaD-5mu5A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 6 SER A 162
ARG A  31
GLY A  27
GLU A  28
 None
 0.76A 5btaA-5mu5A:
undetectable
5btaB-5mu5A:
undetectable
5btaC-5mu5A:
undetectable		 5btaA-5mu5A:
22.13
5btaB-5mu5A:
17.39
5btaC-5mu5A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 6 SER A 162
ARG A  31
GLY A  27
GLU A  28
 None
 0.78A 5btcA-5mu5A:
undetectable
5btcC-5mu5A:
undetectable
5btcD-5mu5A:
2.5		 5btcA-5mu5A:
22.13
5btcC-5mu5A:
22.13
5btcD-5mu5A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 6 SER A 162
ARG A  31
GLY A  27
GLU A  28
 None
 0.74A 5btcA-5mu5A:
undetectable
5btcB-5mu5A:
undetectable
5btcC-5mu5A:
undetectable		 5btcA-5mu5A:
22.13
5btcB-5mu5A:
17.39
5btcC-5mu5A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 7 SER A 162
ARG A  31
GLY A  27
GLU A  28
 None
 0.68A 5btfA-5mu5A:
undetectable
5btfB-5mu5A:
undetectable
5btfC-5mu5A:
undetectable		 5btfA-5mu5A:
22.13
5btfB-5mu5A:
17.39
5btfC-5mu5A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 7 SER A 162
ARG A  31
GLY A  27
GLU A  28
 None
 0.76A 5btfA-5mu5A:
undetectable
5btfC-5mu5A:
undetectable
5btfD-5mu5A:
2.6		 5btfA-5mu5A:
22.13
5btfC-5mu5A:
22.13
5btfD-5mu5A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 7 ILE A 199
ILE A 147
PHE A 228
LEU A 180
 None
 0.76A 5fukA-5mu5A:
undetectable
5fukB-5mu5A:
undetectable		 5fukA-5mu5A:
18.26
5fukB-5mu5A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_A_IPHA101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 4 CYH A 557
LEU A 575
LEU A 598
ALA A 602
 None
 1.14A 5hpuA-5mu5A:
undetectable
5hpuB-5mu5A:
undetectable		 5hpuA-5mu5A:
2.90
5hpuB-5mu5A:
4.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 9 ILE A 277
LEU A 409
ARG A 482
ILE A 480
GLY A 477
 None
None
EDO  A 709 (-3.5A)
None
None
 1.31A 5ifuB-5mu5A:
undetectable		 5ifuB-5mu5A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 11 ARG A 526
ALA A 403
GLY A 397
ILE A 301
VAL A 365
 None
 0.95A 5kr2B-5mu5A:
undetectable		 5kr2B-5mu5A:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_0
(REGULATORY PROTEIN
TETR)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 12 GLN A 141
GLY A 120
SER A 119
GLU A 118
LEU A  74
 None
 1.26A 5vlmF-5mu5A:
4.1		 5vlmF-5mu5A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 12 LEU A 509
VAL A 309
ILE A 284
ASP A 286
ASP A 285
 None
None
None
PG4  A 705 ( 4.7A)
None
 1.44A 6bxnA-5mu5A:
undetectable		 6bxnA-5mu5A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_D_FOZD403_0
(THYMIDYLATE SYNTHASE)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 12 LEU A 638
LEU A 554
GLY A 555
ILE A 550
ALA A 590
 None
 1.41A 6qxsD-5mu5A:
undetectable		 6qxsD-5mu5A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_C_FFOC404_0
(THYMIDYLATE SYNTHASE)		 5mu5 UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 10 PHE A 154
ILE A 184
LEU A 195
LEU A 129
GLY A 128
 None
 1.49A 6r2eC-5mu5A:
undetectable		 6r2eC-5mu5A:
19.69