SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mu7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 5mu7 COATOMER SUBUNIT
BETA
(Chaetomium
thermophilum) 		4 / 6 ILE A  61
TYR A  81
PHE A  97
PHE A 122
 None
 1.46A 1e73M-5mu7A:
undetectable		 1e73M-5mu7A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)		 5mu7 COATOMER SUBUNIT
DELTA-LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 12 GLY B  12
ALA B  34
LEU B  33
ASP B  62
LEU B  61
 None
 1.13A 1i9gA-5mu7B:
undetectable		 1i9gA-5mu7B:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 5mu7 COATOMER SUBUNIT
BETA
(Chaetomium
thermophilum) 		4 / 5 ALA A 204
PHE A 193
ILE A 230
ASP A 233
 None
 1.11A 1yc2D-5mu7A:
undetectable		 1yc2D-5mu7A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 5mu7 COATOMER SUBUNIT
BETA
(Chaetomium
thermophilum) 		4 / 5 LEU A 338
ASP A 305
MET A 320
LEU A 356
 None
 1.28A 2jfaA-5mu7A:
undetectable		 2jfaA-5mu7A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5mu7 COATOMER SUBUNIT
BETA
(Chaetomium
thermophilum) 		5 / 11 LEU A 123
PHE A 122
LEU A 108
SER A 138
VAL A 100
 None
 1.32A 2po5B-5mu7A:
undetectable		 2po5B-5mu7A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 5mu7 COATOMER SUBUNIT
DELTA-LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 9 ILE B 102
ALA B  87
VAL B  90
CYH B  94
 None
 0.88A 2vufB-5mu7B:
undetectable		 2vufB-5mu7B:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 5mu7 COATOMER SUBUNIT
BETA
COATOMER SUBUNIT
DELTA-LIKE PROTEIN
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		3 / 3 TYR A 114
GLU B 115
ASN B 118
 None
 0.93A 2y7hC-5mu7A:
undetectable		 2y7hC-5mu7A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB7_A_NCAA901_0
(PROSTAGLANDIN
REDUCTASE 2)		 5mu7 COATOMER SUBUNIT
BETA
(Chaetomium
thermophilum) 		4 / 5 TYR A  81
ILE A 104
LEU A 126
LEU A 131
 None
 1.14A 2zb7A-5mu7A:
undetectable		 2zb7A-5mu7A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5mu7 COATOMER SUBUNIT
BETA
COATOMER SUBUNIT
DELTA-LIKE PROTEIN
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 LEU B  77
GLN B  78
LEU A 287
PHE A 284
 None
 0.96A 3ag2C-5mu7B:
undetectable		 3ag2C-5mu7B:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5mu7 COATOMER SUBUNIT
BETA
COATOMER SUBUNIT
DELTA-LIKE PROTEIN
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 8 LEU B  77
GLN B  78
LEU A 287
PHE A 284
 None
 0.93A 3ag4C-5mu7B:
undetectable
3ag4J-5mu7B:
undetectable		 3ag4C-5mu7B:
17.22
3ag4J-5mu7B:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5mu7 COATOMER SUBUNIT
BETA
(Chaetomium
thermophilum) 		5 / 12 VAL A 259
ALA A 263
SER A 266
LEU A 267
LEU A 270
 None
 0.77A 3hs6A-5mu7A:
undetectable		 3hs6A-5mu7A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 5mu7 COATOMER SUBUNIT
BETA
(Chaetomium
thermophilum) 		4 / 7 PHE A 212
GLY A 214
PHE A 229
PHE A 193
 None
 1.04A 3ko0D-5mu7A:
undetectable
3ko0E-5mu7A:
undetectable		 3ko0D-5mu7A:
14.96
3ko0E-5mu7A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 5mu7 COATOMER SUBUNIT
BETA
COATOMER SUBUNIT
DELTA-LIKE PROTEIN
(Chaetomium
thermophilum) 		3 / 3 ARG B 122
LEU A 221
THR A 256
 None
 0.84A 3oxcA-5mu7B:
undetectable		 3oxcA-5mu7B:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_A_1KXA277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5mu7 COATOMER SUBUNIT
DELTA-LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 10 TYR B  58
ILE B  69
VAL B  67
TYR B  65
SER B   7
 None
 0.98A 3uprA-5mu7B:
undetectable		 3uprA-5mu7B:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_C_1KXC277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5mu7 COATOMER SUBUNIT
DELTA-LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 10 TYR B  58
ILE B  69
VAL B  67
TYR B  65
SER B   7
 None
 0.98A 3uprC-5mu7B:
undetectable		 3uprC-5mu7B:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5mu7 COATOMER SUBUNIT
BETA
COATOMER SUBUNIT
DELTA-LIKE PROTEIN
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		3 / 3 THR A 187
ASN A 191
GLU B 123
 None
 0.79A 3v4tA-5mu7A:
undetectable
3v4tC-5mu7A:
undetectable		 3v4tA-5mu7A:
22.12
3v4tC-5mu7A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 5mu7 COATOMER SUBUNIT
DELTA-LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 12 TYR B  58
ILE B  69
VAL B  67
TYR B  65
SER B   7
 None
 0.95A 3vrjA-5mu7B:
undetectable
3vrjC-5mu7B:
undetectable		 3vrjA-5mu7B:
21.11
3vrjC-5mu7B:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 5mu7 COATOMER SUBUNIT
BETA
COATOMER SUBUNIT
DELTA-LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 5 LEU A 251
SER A 266
LEU A 224
ASN B  75
 None
 1.21A 4n09C-5mu7A:
undetectable		 4n09C-5mu7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5mu7 COATOMER SUBUNIT
BETA
COATOMER SUBUNIT
DELTA-LIKE PROTEIN
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 5 THR A 119
GLY A 117
GLU B 141
ASP A 107
 None
 1.19A 5c0oH-5mu7A:
undetectable		 5c0oH-5mu7A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 5mu7 COATOMER SUBUNIT
BETA
(Chaetomium
thermophilum) 		3 / 3 LYS A 232
HIS A 201
HIS A 236
 None
 1.32A 5oexA-5mu7A:
undetectable		 5oexA-5mu7A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 5mu7 COATOMER SUBUNIT
BETA
(Chaetomium
thermophilum) 		3 / 3 LYS A 232
HIS A 201
HIS A 236
 None
 1.39A 5oexB-5mu7A:
undetectable		 5oexB-5mu7A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 5mu7 COATOMER SUBUNIT
BETA
(Chaetomium
thermophilum) 		3 / 3 LYS A 232
HIS A 201
HIS A 236
 None
 1.38A 5oexC-5mu7A:
undetectable		 5oexC-5mu7A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 5mu7 COATOMER SUBUNIT
BETA
(Chaetomium
thermophilum) 		3 / 3 LYS A 232
HIS A 201
HIS A 236
 None
 1.36A 5oexD-5mu7A:
undetectable		 5oexD-5mu7A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5mu7 COATOMER SUBUNIT
DELTA-LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 10 TYR B  58
ILE B  69
VAL B  67
TYR B  65
SER B   7
 None
 0.97A 5u98A-5mu7B:
undetectable		 5u98A-5mu7B:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_D_1KXD301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5mu7 COATOMER SUBUNIT
DELTA-LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 10 TYR B  58
ILE B  69
VAL B  67
TYR B  65
SER B   7
 None
 0.98A 5u98D-5mu7B:
undetectable		 5u98D-5mu7B:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_B_SAMB401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 5mu7 COATOMER SUBUNIT
BETA
(Chaetomium
thermophilum) 		5 / 12 TYR A 375
VAL A 325
ARG A 335
VAL A 333
ASP A 332
 None
 1.39A 6bxlB-5mu7A:
undetectable		 6bxlB-5mu7A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 5mu7 COATOMER SUBUNIT
BETA
(Chaetomium
thermophilum) 		4 / 7 ALA A 279
LYS A 283
GLU A 286
LEU A 315
 None
 1.09A 6ci6A-5mu7A:
2.1		 6ci6A-5mu7A:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_D_READ601_1
(RETINOIC ACID
RECEPTOR)		 5mu7 COATOMER SUBUNIT
BETA
(Chaetomium
thermophilum) 		4 / 7 VAL A 325
LEU A 356
LEU A 318
GLY A 282
 None
 0.74A 6eu9D-5mu7A:
undetectable		 6eu9D-5mu7A:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_B_FFOB403_0
(THYMIDYLATE SYNTHASE)		 5mu7 COATOMER SUBUNIT
BETA
COATOMER SUBUNIT
DELTA-LIKE PROTEIN
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		5 / 10 PHE B 113
ILE B 116
ASN B 124
LEU A 221
GLY B 120
 None
 1.47A 6r2eB-5mu7B:
undetectable		 6r2eB-5mu7B:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_C_FFOC404_0
(THYMIDYLATE SYNTHASE)		 5mu7 COATOMER SUBUNIT
BETA
COATOMER SUBUNIT
DELTA-LIKE PROTEIN
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		5 / 10 PHE B 113
ILE B 116
ASN B 124
LEU A 221
GLY B 120
 None
 1.45A 6r2eC-5mu7B:
undetectable		 6r2eC-5mu7B:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_D_FFOD403_0
(THYMIDYLATE SYNTHASE)		 5mu7 COATOMER SUBUNIT
BETA
COATOMER SUBUNIT
DELTA-LIKE PROTEIN
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		5 / 10 PHE B 113
ILE B 116
ASN B 124
LEU A 221
GLY B 120
 None
 1.47A 6r2eD-5mu7B:
undetectable		 6r2eD-5mu7B:
19.45