SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mua'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5mua RICIN B-RELATED
LECTIN
(Polyporus
squamosus) 		5 / 12 LEU A 234
ALA A 229
VAL A 219
GLN A 186
ARG A 256
 None
 1.26A 1kt4A-5muaA:
undetectable		 1kt4A-5muaA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5mua RICIN B-RELATED
LECTIN
(Polyporus
squamosus) 		5 / 11 LEU A 234
ALA A 229
VAL A 219
GLN A 186
ARG A 256
 None
 1.28A 1kt7A-5muaA:
undetectable		 1kt7A-5muaA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5mua RICIN B-RELATED
LECTIN
(Polyporus
squamosus) 		4 / 7 GLN A 268
ALA A 249
PHE A 206
ASN A 251
 E64  A 304 ( 4.9A)
E64  A 304 ( 4.3A)
None
None
 1.37A 1t9wA-5muaA:
undetectable		 1t9wA-5muaA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5mua RICIN B-RELATED
LECTIN
(Polyporus
squamosus) 		5 / 12 LEU A 182
GLU A 225
GLY A 223
ASN A 226
ALA A 229
 None
 1.23A 2bm9B-5muaA:
undetectable		 2bm9B-5muaA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_A_SAMA1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 5mua RICIN B-RELATED
LECTIN
(Polyporus
squamosus) 		4 / 4 SER A 188
GLU A 255
GLN A 147
ASP A 185
 None
 1.28A 2cl5A-5muaA:
0.0		 2cl5A-5muaA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 5mua RICIN B-RELATED
LECTIN
(Polyporus
squamosus) 		4 / 6 SER A 188
GLU A 255
GLN A 147
ASP A 185
 None
 1.28A 2cl5B-5muaA:
undetectable		 2cl5B-5muaA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 5mua RICIN B-RELATED
LECTIN
(Polyporus
squamosus) 		4 / 6 SER A 188
GLU A 255
GLN A 147
ASP A 185
 None
 1.24A 2zvjA-5muaA:
undetectable		 2zvjA-5muaA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5V_A_ACTA511_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5mua RICIN B-RELATED
LECTIN
(Polyporus
squamosus) 		4 / 4 ASN A 258
PHE A 259
SER A 260
GLN A 151
 None
 1.14A 3v5vA-5muaA:
undetectable		 3v5vA-5muaA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 5mua RICIN B-RELATED
LECTIN
(Polyporus
squamosus) 		3 / 3 ASP A  72
GLY A  75
TYR A  87
 GAL  A 301 (-2.7A)
GAL  A 301 (-3.4A)
GAL  A 301 (-3.5A)
 0.46A 3w9tC-5muaA:
8.3		 3w9tC-5muaA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 5mua RICIN B-RELATED
LECTIN
(Polyporus
squamosus) 		3 / 3 ASP A  72
GLY A  75
TYR A  87
 GAL  A 301 (-2.7A)
GAL  A 301 (-3.4A)
GAL  A 301 (-3.5A)
 0.45A 3w9tG-5muaA:
17.4		 3w9tG-5muaA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 5mua RICIN B-RELATED
LECTIN
(Polyporus
squamosus) 		3 / 3 GLN A 147
ASP A  43
GLN A 186
 None
 0.89A 4aztA-5muaA:
undetectable		 4aztA-5muaA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 5mua RICIN B-RELATED
LECTIN
(Polyporus
squamosus) 		3 / 3 GLU A 112
ASP A  93
ASP A  72
 None
None
GAL  A 301 (-2.7A)
 0.79A 4gc9A-5muaA:
undetectable		 4gc9A-5muaA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_1
(CATECHOL
O-METHYLTRANSFERASE)		 5mua RICIN B-RELATED
LECTIN
(Polyporus
squamosus) 		4 / 5 SER A 188
GLU A 255
GLN A 147
ASP A 185
 None
 1.26A 5fhrB-5muaA:
undetectable		 5fhrB-5muaA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 5mua RICIN B-RELATED
LECTIN
(Polyporus
squamosus) 		4 / 7 GLN A 186
TRP A  49
ALA A  22
LEU A  21
 None
 1.06A 5nwvA-5muaA:
undetectable		 5nwvA-5muaA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5mua RICIN B-RELATED
LECTIN
(Polyporus
squamosus) 		3 / 3 GLN A 186
TRP A 222
VAL A 219
 None
 1.05A 6auuA-5muaA:
undetectable		 6auuA-5muaA:
18.98