SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mun'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 5mun LYS-GINGIPAIN W83
(Porphyromonas
gingivalis) 		4 / 6 PHE A  47
ILE A 194
VAL A 196
PHE A  43
 None
 0.71A 2cizA-5munA:
undetectable		 2cizA-5munA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 5mun LYS-GINGIPAIN W83
(Porphyromonas
gingivalis) 		4 / 8 PHE A  49
ALA A  28
ASN A 191
THR A  34
 None
 1.13A 3t3sE-5munA:
undetectable		 3t3sE-5munA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 5mun LYS-GINGIPAIN W83
(Porphyromonas
gingivalis) 		5 / 12 LEU A 186
GLU A  53
VAL A  67
PRO A  84
THR A  33
 None
None
None
None
AZI  A 301 (-4.6A)
 1.33A 4hvcB-5munA:
undetectable		 4hvcB-5munA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5mun LYS-GINGIPAIN W83
(Porphyromonas
gingivalis) 		4 / 8 ASN A  50
GLU A  51
GLU A  53
TYR A 179
 None
 1.10A 4mj8A-5munA:
undetectable
4mj8C-5munA:
undetectable		 4mj8A-5munA:
20.80
4mj8C-5munA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 5mun LYS-GINGIPAIN W83
(Porphyromonas
gingivalis) 		3 / 3 ASN A 141
ALA A 143
ARG A 147
 None
 0.11A 5cvtB-5munA:
undetectable		 5cvtB-5munA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_D_HFGD1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 5mun LYS-GINGIPAIN W83
(Porphyromonas
gingivalis) 		5 / 12 LEU A 186
GLU A  53
VAL A  67
PRO A  84
THR A  33
 None
None
None
None
AZI  A 301 (-4.6A)
 1.43A 5xipD-5munA:
undetectable		 5xipD-5munA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5mun LYS-GINGIPAIN W83
(Porphyromonas
gingivalis) 		5 / 12 LEU A 186
GLU A  53
VAL A  67
PRO A  84
THR A  33
 None
None
None
None
AZI  A 301 (-4.6A)
 1.32A 5xiqB-5munA:
undetectable		 5xiqB-5munA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 5mun LYS-GINGIPAIN W83
(Porphyromonas
gingivalis) 		4 / 6 PHE A  64
GLY A  61
THR A  59
GLN A 124
 None
 1.14A 6ag0A-5munA:
undetectable		 6ag0A-5munA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 5mun LYS-GINGIPAIN W83
(Porphyromonas
gingivalis) 		4 / 6 PHE A  64
GLY A  61
THR A  59
GLN A 124
 None
 1.11A 6ag0C-5munA:
2.1		 6ag0C-5munA:
15.42