SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5muw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_1
(ESTROGEN RECEPTOR)		 5muw PACKAGING ENZYME P4
(Pseudomonas
virus
phi6) 		5 / 12 THR A  43
ALA A  47
GLU A  50
LEU A 177
LEU A 180
 None
 1.21A 1errB-5muwA:
undetectable		 1errB-5muwA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 5muw PACKAGING ENZYME P4
(Pseudomonas
virus
phi6) 		4 / 6 PHE A 220
HIS A 110
ALA A 179
GLY A 176
 None
 1.06A 1gfzA-5muwA:
undetectable		 1gfzA-5muwA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5muw PACKAGING ENZYME P4
(Pseudomonas
virus
phi6) 		4 / 6 PHE A 220
HIS A 110
ALA A 179
GLY A 176
 None
 1.05A 1l7xA-5muwA:
undetectable		 1l7xA-5muwA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_D_URFD999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 5muw PACKAGING ENZYME P4
(Pseudomonas
virus
phi6) 		4 / 4 MET A  49
ALA A  46
TYR A  44
ILE A  45
 None
 1.27A 1upfD-5muwA:
undetectable		 1upfD-5muwA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)		 5muw PACKAGING ENZYME P4
(Pseudomonas
virus
phi6) 		5 / 11 VAL A 144
ILE A  64
ILE A 172
VAL A 186
VAL A 184
 None
 1.08A 2nnpB-5muwA:
undetectable		 2nnpB-5muwA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 5muw PACKAGING ENZYME P4
(Pseudomonas
virus
phi6) 		5 / 12 LEU A  20
ILE A  36
ILE A  75
ILE A  41
ILE A 216
 None
 1.08A 2ygoA-5muwA:
undetectable		 2ygoA-5muwA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5muw PACKAGING ENZYME P4
(Pseudomonas
virus
phi6) 		4 / 6 PHE A 220
HIS A 110
ALA A 179
GLY A 176
 None
 1.07A 3dd1B-5muwA:
undetectable		 3dd1B-5muwA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5muw PACKAGING ENZYME P4
(Pseudomonas
virus
phi6) 		5 / 12 ILE A 172
THR A  73
ILE A 146
ILE A 164
SER A 165
 None
 1.27A 3kpbC-5muwA:
undetectable		 3kpbC-5muwA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5muw PACKAGING ENZYME P4
(Pseudomonas
virus
phi6) 		5 / 10 ILE A 172
THR A  73
ILE A 146
ILE A 164
SER A 165
 None
 1.26A 3kpbD-5muwA:
undetectable		 3kpbD-5muwA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_A_15UA301_1
(THROMBIN HEAVY CHAIN)		 5muw PACKAGING ENZYME P4
(Pseudomonas
virus
phi6) 		5 / 10 HIS A 163
LEU A 145
ALA A 185
ALA A 161
TRP A 148
 None
 1.48A 4rn6A-5muwA:
undetectable		 4rn6A-5muwA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 5muw PACKAGING ENZYME P4
(Pseudomonas
virus
phi6) 		4 / 4 LEU A 180
ILE A  10
HIS A   9
VAL A  13
 None
 1.22A 4xyzA-5muwA:
undetectable		 4xyzA-5muwA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 5muw PACKAGING ENZYME P4
(Pseudomonas
virus
phi6) 		4 / 7 LEU A 158
ASP A 159
ALA A  60
LEU A  59
 None
 1.12A 5nwvA-5muwA:
undetectable		 5nwvA-5muwA:
11.22